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Essay on therapies in hemophilia
Essay on therapies in hemophilia
Essay on therapies in hemophilia
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Adriana Parham English I Part II Assignment 3_6
JM1503296
“A Study of Hemophilia, Mortality Rates, and Its History”
By Adriana Parham, James Madison High School Student
2018
Abstract
Hemophilia is one of the oldest inherited blood disorders, dating back to as far the 2nd century A.D. Low levels of the blood clotting proteins Factor VIII and Factor IX are what cause this blood disorder. Symptoms in people who are affected by this blood disorder, are internal bleeding, bleeding for prolonged periods of time after surgery or injury, spontaneous bleeding in the joints, and nosebleeds. Also, people with inhibitors may be at increased risk for joint disease, or even death if they are not diagnosed early enough.
An Introduction to Hemophilia, Data, and Statistics
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According to the Centers of Disease Control and Prevention (CDC, 2017), Hemophilia A affects 1 in 5000 male births, and 400 babies are born with Hemophilia A each year. Hemophilia A, and Hemophilia B are two of the most common types of Hemophilia. Hemophilia A is caused by low levels of the blood-clotting factors known as Factor VIII, and Hemophilia B is caused by low levels of the blood clotting factor known as Factor
○ ABO incompatibility. People with an O blood type have antibodies that can attack blood cells in type A or B blood. If a mother 's blood type is O and her baby 's blood type is A or B, her antibodies may destroy the baby 's red blood cells and cause hemolytic disease.
The severity of hemophilia varies greatly. Hemophilia A and Hemophilia B are the most common genetic bleeding disorders. Hemophilia A is observed in 80 percent of hemophiliacs and is a deficiency or absence of Factor VIII. It can also be referred to as "classic" hemophilia. In the second most common, hemophilia B, factor IX is missing.
In the early 1980s, most people with Hemophilia were injected with “HIV”, because the factors used for treatment were isolated from injected human plasma. Since then, “virus sterilizing techniques” and the use of “artificial factors” have greatly reduced this risk. Hemophilia A can also be known as classic Hemophilia (because it is more common) and factor VIII deficiency. Hemophilia B is also known as Christmas disease, and factor IX deficiency.
Hemophillia is a rare bleeding disorder in which the blood does not clot normally. Hemophillia is usually inherited and people born with it have little or no clotting factor (a protein needed for normal blood clotting). These proteins work together with platelets to help the blood clot. When blood vessels are injured, clotting factors help platelets stick together to plug cuts and breaks on the vessels. Hemophillia usually occurs in males with about 1 in every 5 000 males being born with the disease each year. A hemophiliac does not bleed more intensely than a person without it but can bleed for a much longer time. In some severe cases, continuous bleeding occurs after minor trauma or can even happen spontaneously.They may also bleed inside their body(internally), especially in the knees, ankles, and elbows. The bleeding can damage organs and tissues and may be life threatening. There are two main types of hemophilia: A and B. People born with type A are missing or have low levels of clotting factor VIII (1 in 5 000 males). People born with type B are missing or have low levels of clotting factor IX (1 in 20 000 males). About 8 out of 10 people who have hemophillia have type A. The greatest concern for both types is deep internal bleeding and bleeding into joints. Hemophilia is a life long disease, but with proper treatment and self-care, most people maintain an active productive lifestyle.
Tsar Nicholas II and his Tsarina, Empress Alexandra, had only one son, Tsarevich Alexei. However, Alexei had inherited from his great-grandmother Queen Victoria the life-threatening genetic disease hemophilia B, a sex-linked genetic disease on the X chromosome that caused a condition of deficiency in blood-clotting and excessive bleeding, symptoms that usually remain hidden unless contracted by a male (Fuhrmann 37; King 28). To Nicholas II, it was imperative that he have a son to succeed him to secure the throne. Alexei was Nicholas’s sole male heir, giving Nicholas the incentive to protect his son at all costs. Without a scientific cure for the genetic disease, Alexandra turned to religion, namely Grigori Rasputin, a poor uneducated Siberian peasant to protect her son.
Hemophilia is a genetic disorder in which the blood does not clot normally. It’s a rare bleeding disorder that has been happening since ancient times. Men are the ones mainly affected by it. One in five thousand men born each year have Hemophilia. Yet women can be carriers and just like men, they can suffer from symptoms too. Women can only have Hemophilia if their father does and mother is a carrier, it’s uncommon but can happen. Hemophilia affects all races and ethnic groups. It’s all based on your family tree. A man with Hemophilia will pass the gene down to his daughters, leading to them becoming carriers. A woman with the gene has a fifty percent chance of passing the gene down on to her sons. If there was no family history of Hemophilia but the woman is a carrier, a son could possibly be the first one in the family to have it. If there’s one thing for certain about hemophilia is that it does not discriminate against anyone. Hemophilia has affected royalty as well as high and low class men all throughout history.
Over one million Americans in the United States are living with or have been diagnosed with leukemia. That’s a big amount of people. I chose to do my research paper on leukemia because two years ago I lost my grandma to the cancer. I wanted to know more about the disease and what was happening to her. I researched the different types, risk factors, symptoms, treatment, and what kind of research is being done to help cure leukemia. Leukemia is a cancer of the blood cells that start in the bone marrow. During leukemia the bone marrow starts to make a lot of abnormal white blood cells or “leukemia cells”.
Hemophilia is a rare genetic blood clotting disorder that primarily affects males. People living with hemophilia do not have enough of, or are missing, one of the blood clotting proteins naturally found in blood. Two of the most common forms of hemophilia are A and B. In persons with hemophilia A (also called classic hemophilia), clotting factor VIII is not present in sufficient amounts or is absent. In persons with hemophilia B (also called Christmas disease), clotting factor IX is not present in sufficient amounts or is absent. People with hemophilia do not bleed more profusely or bleed faster than normal; they bleed for a longer period of time.
Today i'm going to be talking about Hemophilia and the general overview of it. I will also talk about any potential cures. I will be talking about what Hempohilia can do to your body. I will also be talking about if theres a cure or just a treatment to make it less worse. I will also be talking about how people with Hemophilia deal with this disease. I will also explain how people will benefit from extended research on thi s topic. I’ll also talk about my personal opininon on this topic and what I think about it. So for my first question I’m explaining what the characteristics of Hemophilia are. The characteristics of Hemophilia are not very deadly but can be very annoying I’ll also explan the genetic causes of this disease.
Hemophilia is a serious genetic condition caused by a coagulation factor that causes a mutation in the f8 and f8 gene. Hemophilia can be treated but not cured. Further studies are currently being done today. Living with hemophilia can be very difficult .physical activity is not recommended for individuals living with this condition. Also surgery is highly dangerous because of the excessive bleeding. In society we have set backs but we have to learn to deal with them.
Hemochromatosis is a disorder that can be inherited from your parents but can also be obtained due to excessive consumption of alcohol or iron or blood transfusions. Hemochromatosis is a disorder that causes your body to absorb more iron than it needs. It then stores the iron in crucial parts of your body like your heart, liver, pancreas, brain, and joints. If the iron continues to built it would lead to iron overload. Iron overload can be fatal because of excessive iron in your heart and liver. Continuous iron overload could lead to serious heart conditions like heart attack and heart failure, it could also lead to liver problems, diabetes mellitus, and possibly cancer and death. Symptoms like diabetes mellitus can be avoided if Hemochromatosis
I haven’t met a person who doesn’t enjoy or love sex but I haven’t met or known someone who has weird way to enjoy it. I found out many type of paraphilia, but foremost let me tell you what paraphilia means it’s an abnormal sexual desire. Let me share you what I haven’t heard or known before, first is the klismaphilia this is the most disgusting some people get arousal from receiving enemas! Pedophilia I just recently learn that there is a term for people who has fantasy having sex with children. Sexual masochism is the arousal of experiencing pain during intercourse and sexual sadism is the opposite this is arousal when inflicting pain to be honest I’ve seen some fetish toys online and the purpose of it its just beyond me. Telephone scatologia
I am to write about an animal that is not very well known by the general populous. This animal must also be a natural resident of the continent of Africa. Rather than report one of the countless deer or goat-like quadrupeds of Africa, I am reporting an animal more microbial in nature. The animal this paper about is known as Onchocerca volvulus.
The second one is beta thalassemia. This occurs when similar gene defects affect production of the beta globin protein. It happens mostly in people of Mediterranean origin, Chinese, other Asians, and African Americans. You need both alpha- and beta-globin to make hemoglobin. If you have one damaged gene, you may have mild anemia and probably won't need treatment. This is called beta thalassemia minor or beta thalassemia trait. It happens when you get a normal gene from one parent and a thalassemia gene from the other. When both genes are damaged, it means you got a thalassemia gene from each parent. You may have moderate or severe anemia. If you have moderate anemia, you may n...
Hematology is the study of blood in health and disease. Some problems that you probably know is red blood cells, white blood cells, platelets, blood vessels, bone marrow, lymph nodes, spleen, and the proteins involved in bleeding and clotting. They are a medical doctor who applies their specialized knowledge to treat patients with blood conditions. This is important because if something is wrong with your blood it can affect you in a really negative way. There are also many different types of blood disorders.