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What is the historical significance of the human genome project
Human genome project
Human genome project
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Before I tell you the various reasons why Genomics is a rather big boon for medication and if used in the right way can save innumerable lives. I will tell you what Genomics really is. Genomics is a discipline in genetics that is concerned with an organism’s DNA sequencing and analysis. The structure of DNA is made up of two twisting pairs of strands which are often described as double helix.DNA is made up of four chemical units called nucleotide bases which include adenine (A) ,Thymine (T),Guanine (G) and Cytosine (C). Bases on opposite pair of the strands pair precisely with specific units. An A pairs with a T and a C always pairs with a C. This pairing provides information of that particular DNA molecule. An organism’s complete set of DNA …show more content…
Bases exist in pairs and the nature of the bases in pair determines the other member of the pair and as a result scientists do not study both the bases of a pair. DNA analysis are used in a variety of places like in a crime scene to gather evidence .After gathering the DNA sample it goes to a forensic lab. Public labs are frequently joint with law enforcement offices .Genomics is related with genes and virtually every part of our body consists of some or the other basis of genes. Till recently genes were only associated with some birth defects or a limited number of diseases but with the recent development in biotechnology genes are used in treating almost every …show more content…
Diseases such as cancer, diabetes and many cardiovascular diseases constituting the majority of health problems in the world could also be eradicated from the face of the earth in a decade if this becomes the reality. Even right now genome-based research has led to many medical researchers and scientists creating improvement in the diagnostics in the medical clinic and also increasing the efficiency of the clinic. So it is safe to say that the role of genetics in medical care has changed drastically and the first examples of the era of genomic medicines are upon us. However genetics remains one of the factors of developing the most common disease but more detailed understanding of genetics can enlighten us with the basic components of the cell and eventually explain how all the elements work together in an efficient way to affect the human anatomy in both time of health and time of disorder or diseases. The study of genomics first came into existence with the start of the project Human Genome Project (HGP) in 2003. There has been much progress in Genomics since a draft research about Genomics was published more than ten years ago. Also as I
It helps medics to find a direct genetic cause of the patient’s condition and target it with pharmaceutical or other therapies. The technology is used for the identification of DNA sequences that increase risks of current diseases and disorders; with this information carriers can start to make efforts to prevent them before the development of the problem. The video mentioned 200 actionable genes, structures that have direct links with a specific condition. Knowing about their presence, people have a chance to bring in preventive measures like taking anticoagulants in the case of identification of a thrombogenic gene. The technology led to the significant improvement of diagnostics and personalized treatments. It helped to find a rare, life-threatening mutation in case of Beery twins and assign a drug to a girl (Alexis) that returned her to a normal life. In the case of cancer genome sequencing led to the development of genetic drags, which target essential tumor genes and make malign structures to shrink. The video mentioned a product that works with the BRАF protein that induces cells to uncontrolled division; the drug led to the remission in the patient with metastasizing melanoma. Such treatment was effective in the case of cystic fibrosis. In the case of the breast cancer the technology helps to evaluate the aggressiveness of the condition and make a personalized decision about chemotherapy. The video also mentioned the pre-implantation genetic diagnosis – an early-staged technology that prevents the development of inherited disorders in
Many things have impacted both the Science and Medical fields of study. Electrophoresis and DNA Sequencing are two of these things. Together they have simultaneously impacted both of these fields. On one hand, there is Electrophoresis. Electrophoresis is a specific method of separating molecules by their size through the application of an electric field. It causes molecules to migrate at a rate and distance dependent on their size. On the other hand, there is DNA Sequencing. DNA Sequencing is a technique used to determine the exact sequence of bases
Although there is so little that can be done to change those inherited genes that an individual may have, scientific research has proved that for every possible disease affecting humans ' well-being there is a genetic component where the body responds. The main point in genetics reactions is whether we activate a gene response or we keep it inactive by following healthy lifestyle choices. The science and research on genetics is expanding and this field will help in the development and advances of health science, which will greatly contribute to the enhancement of individuals ' well-being (Durch, Bailey, and Stoto
strands which make up the letters of a genetic code. In certain regions of a DNA strand
In 1990, the first great stride of genetics took place. This was called the Human Genome Project, a large-scale operation that was designed to understand the human genome (genetic structure). Since its commencement, there have been many leaps and bounds that have taken place. For certain genetic issues that we once knew nothing about, we no...
Genetics can predetermine many things for an individual but health and prevention can aid in the prevention of the expression of some genes. This is why it is important for healthcare providers to promote their patient’s awareness of what he or she is at risk for so that they can live the healthiest life possible. It is much easier to prevent a disease than it is to cure one. As healthcare providers it is our responsibility to cure illnesses, sure, but more importantly it is our responsibility to prevent disease and increase our patient’s quality of
Man I got some stuff that would make you live longer , But if not your life going be crazy for the rest of your life!!!!
DNA analysis is a scientific process among the newest and most sophisicated of techniques used to test for genetic disorders, which involves direct examination of the DNA molecule itself (Lyman, 2014) . Today crime labs use mtDNA analysis. This type of analysis allows smaller degraded pieces of DNA to still be successfully tested (Lyman, 2014) . There are several steps taken when analyzing DNA in forensics. When testing scientists must first isolate the DNA so it is not contaminated and can't be used. Lab technicians the take small pieces of the DNA, conserving as much as they can encase they need to test again. Once testing is done the next step is determining the DNA test results and finally there is the comparison and interpretation of the test results from the unknown and known samples to determ...
Once the project began in 1990, fewer than one hundred human sickness genes had been known. At the project 's conclusion in 2003, the quantity of known sickness genes had up to over fourteen-hundred, however, the human order project centered on the polymer sequence of a personal. The results of human genome project results in significant improvement of the medicines for different diseases. The project initiated by the government enables the researchers and the doctors to understand the etiology of less known disease. After knowing the factors behind the disease, researchers tried to find out the medicines which could treat those diseases and diminish their effects. It also made the world aware of the fact that genes could be used for the research and medical purposes in the field of medicine. As a result of this project, it became very easy to produce the clones and the genes by performing the gene sequencing and different analysis on the genes of a person. The future of this project, doctors will become completely able to understand the hidden causes of the disease which will later on help in understanding the management of their
Can you imagine knowing your own genetic code? Going into the doctor for a routine physical and leaving with the knowledge of your genetic downfalls so that you may prevent disease and cancers. This may seem unbelievable but it is likely to be implemented in the near future. Since the start of the human genome project, the medical community has been anxiously awaiting its completion because the applications it has to this field are obviously enormous. However, we still have much to learn about genetic variability and the information we gain can be used to prevent, repair, and eradicate illness.
The use of genetic sequencing in the medical field has innumerable possibilities; genomic medicine, as this new field is now called, will enable the human race to make immense advances in understanding how our genetic heredity makes us susceptible to some illnesses and immune to others. The detection of diseases with a high rate of heredity is just one facet of the gem that is genomics; once researchers are able to map out all of the vital components and rare alleles that sometimes play a large factor in disease, it will be possible to target these specific gene combinations, functional elements, and alleles. Because of the fact that protein, produced by our cells’ ribosomes, has an effect on the pathways that help express our inherited traits, it is important that we understand the relationship between DNA and protein, and how this affects the phenotype of an individual’s genetic attributes. For example, sickle-cell anemia is caused by a flaw in one nitrogenous base sequence in DNA. This flaw then translates into RNA, then into amino acids that determine the phenotype that the subject will have. The discrepancy in something as minute as a nitrogenous base and one amino acid makes the difference between a healthy, normal life and a life ...
In April 2003, researchers successfully completed the Human Genome Project, more than two years ahead of schedule. The Human Genome Project has already led to the discovery of more than 1,800 genes that cause disease (“NIH Fact Sheets…”). As a result of the Human Genome Project, researchers can find a gene suspected of causing an inherited disease in a matter of days, rather than the years it would have taken before. “One major step was the development of the HapMap. The HapMap is a catalog of common genetic differences in the human genome. The HapMap has accelerated the search for genes that have a say in common human disease, and have already produced results in finding genetic factors involved in conditions ranging from age-related blindness to obesity”(NIH Fact Sheet). The Can...
The scientific and medical progress of DNA as been emense, from involving the identification of our genes that trigger major diseases or the creation and manufacture of drugs to treat these diseases. DNA has many significant uses to society, health and culture of today. One important area of DNA research is that used for genetic and medical research. Our abi...
Another area of medical advancement is genetic engineering. Genetic engineering will detect and possibly stop diseases before birth. Many diseases are associated with specific genes that can be checked for disease and replaced if dysfunctional. Genetic testing has already revealed genetic mutations that cause hypertension, heart disease, diabetes, osteoporosis, colon cancer, polycystic kidney disease, Alzheimers disease, and others. (5) Replacing missing, altered, inactive, or dysfunctional genes will prevent diseases or even death. Also, progression of a disease can be monitored, and
For example such as medicine, it can be sometime possible to reading DNA sequences and find out how some diseases occur. It can sometimes be possible to fight some infectious diseases or any form of disease by changing the DNA codons which cause most of these problems.