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Ewing sarcoma
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Ewing Sarcoma Diagnosis and Treatment
Makaylah Mutz
Biology 1501
Professor Benard
April 19, 2018
Introduction
Ewing Sarcoma is a form of cancer that starts growing as tumors in bones and close to the soft tissues that are grouped near bones. Any cells in the body can become cancerous and then can move throughout the body. Any form of cancer begins by the rapid division of cells and that end up growing out of control crowding out the normal body cells. Ewing Sarcoma tends to have gene of DNA the fuses into abnormalities and consist of proteins that are not found or are rarely found within other forms and types of cancers. Ewing Sarcoma is generally found in three main areas of the body: the legs - more specifically
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During the physical examination the doctor will be looking for any areas that are causing the patient pain and areas that might have some swelling. When pain or swelling is found there are other test that can be run, such as: X-rays, Magnetic resonance imaging scan (MRI), Computed tomography scan (CAT scan), bone scan and a Positron emission tomography scan (PET scan). These scans are performed for the doctors to get a better look at the area in question and to determine the extent of the tumor. If the images from the scans suggest that there is a tumor and that it might be an Ewing tumor a biopsy of the tumor will be ordered. A biopsy of the tumor in question will help to determine if the tumor is either an Ewing’s tumor or some other cancer or that the tumor is a benign tumor which then would mean that the mass of cells is not cancerous. Most biopsies are taken by extracting a sample of the tumor (Scientific Research Publishing) and the later viewing the samples taken under a microscope. Sometimes if the tumor is in a good location and is small the surgeon can remove it completely and observe the entire tumor. Once a diagnosis has been made tests such as a bone marrow aspiration and biopsy test and blood test are done so that doctors can track the spread of the cancer to the bone marrow …show more content…
When receiving radiation therapy high-energy beams are pointed in the location of the tumor (s). This treatment method can be used instead of surgery or coupled with surgery depending on the complexity of removing the cancerous tumor. When receiving this form of treatment, it is in most cases given about 5 days on average a week for a certain number of weeks. With each treatment of radiation, the patient will be gradually receiving a higher dose of high-energy beams then in the previous radiation therapy session. Radiation therapy itself only takes a couple minutes but getting the radiation machine and the patient in place for treatment may take a much longer amount of time then the actual treatment. With any type of cancer treatment there are going to be some side effects. Some short-term side effects are patches on the skin that look like sun burn and hair loss also in the area where the radiation was aimed. Long-term effects are organ function depending on where the treatment was given and in some cases nerve damage and can also cause headaches and trouble thinking. A major concern with this form of Ewing tumor treatment is the fact that a new form of cancer can develop in the area where the patient had once received radiation
If a lymph node is still enlarged then a lymph node biopsy is the only way to find out for sure, a sample of the lymph node is looked at under a microscope this procedure can be done at a day surgery unit and a patient can usually return home that same day. A CT scan can also be used to take a picture of the whole body to see all of the nodes that are affected and it can tell doctors on the best course of treatment for each individual patient. Once diagnosis of lymphoma it is also important to find out if the cancer has spread to the bone marrow so further test will be done and it has become best practice that a CT scan and a PET scan should be carried out at the start and half way thought treatment to see how the cancer has been affected and if treatment needs to be stepped up or back depending
Sarcoma is a cancer that arises from mesenchyme-originated cells (i.e., bone or muscle) and can be either bone or soft tissue. Carcinoma is a cancer that arises from epithelial cells ("What is a soft tissue sarcoma?").
There are essentially three main types of cancer treatments; surgery, chemotherapy, and radiation. Surgery allows doctors to effectively remove tumors from a clear plane. Chemotherapy uses drugs to treat the tumor; but often the drugs affect other healthy cells in the process. Using radiation as a treatment can be either precise or vague. Many health stigmas can come from the vague forms of radiation or conventional radiation therapy. Conventional radiation treats both the unhealthy and healthy cells, therefore exposing healthy cells to harmful radiation (Radiation Oncology, 2011, p.6). When healthy cells are exposed to gamma radiation they are also exposed to ionizing radiation. The ionization can cause “breakage of chemical bonds or oxidization (addition of oxygen atoms)” in a cell; the main impact of this is on a cell’s DNA, if two strands of DNA break it can result in “mutations, chromosome aberrations, ...
Osteosarcoma, characterized as a neoplasm that produces osteoid, is a highly malignant tumor that develops predominantly in the metaphysis of the long bones, often in the distal femur and proximal tibia. More rare osteosarcomas may develop in the soft tissue. Although the malignancy usually arises in the medullary cavity of the metaphysis of a growing tubular long bone, less frequent growth patterns can develop on the surface on the bone. Surface osteosarcomas, as well as being significantly rarer, are also of a low grade, where else medullary osteosarcomas are of an aggressive nature, making it high grade. Osteosarcomas may also be confined to the cortex, and can even originate in an extraskeletal site.
Cancer is a disease in which cells multiply out of control and gradually build a mass of tissue called a tumor. There has been a large amount of research dedicated to the treatment and cure of cancer. Several types of treatments have been developed. The following are just some of the major examples of cancer therapy: surgery, chemotherapy, radiation therapy, biologic therapy, biorhythms, unconventional treatments, and hyperthermia. Each type of treatment is discussed in detail below.
Although there is no early detection test for mesothelioma, there are several tests that can be used to help in making the diagnosis of mesothelioma, including a chest x-ray, a CT scan, or an MRI scan. A chest x-ray yields an image of the lungs that will show many types of abnormal changes. A CT scan is a type of x-ray, but it uses a computer rather than film to create detailed images. An MRI scan uses magnetism, radio waves, and a computer but does not utilize radiation to create a clear image. These tests help your doctor differentiate mesothelioma from other lung tumors as well as determine where the tumor is and its size. Your doctor may need to remove a tissue sample from the tumor or draw fluid from it to confirm it to confirm the diagnosis.
In addition to an endoscopy, a biopsy may be recommended. During a biopsy, a small piece of tissue is removed from an inflamed area. This piece of tissue is then examined in pathology in order to determine whether either disease is present or not.
For cancer patients there are several treatment options. Surgery can remove cancerous tumors, chemotherapy uses drugs for treatment, and radiation therapy. The doctor in charge of the patient’s treatment may also choose to use radiation therapy. “Radiation
The purpose of this paper is to describe the diagnosis and staging of cancer, complications of cancer, the side effects of the cancer treatment, and methods to lessen the physical and psychological effects of cancer.
If one is affected by cancer, there are treatments to help take away this illness affecting their body. This essay is about a specific type of treatment for cancer, radiation therapy. There are different types of forms of particles for radiation, for example, protons and waves like x-rays and visible light. These types of radiations are grouped on how much energy they contain because they can cause different effects. A low type of energy radiation can be radio waves and heat, also known as non-ionizing radiation.
Annette could not take that as a final answer and told her that she would not just leave it and should get a second opinion and have another test run. The patient went back and requested a more thorough test be completed, she got the results back and everything was clear and her primary care physician assured her she was fine. Initially she would perform the exams as learned in school, but now after finding something abnormal, she now does a more thorough check, especially on patients with a previous history of cancer. This incident solidified her belief in early detection and proper documentation.
Radiation therapists work closely with patients to fight cancer. According to Health Care Careers, Oncologists, Dosimetrists and nurses are some of the professionals that a radiation therapist works with while caring for a cancer patient. This group of professionals will determine a specialized treatment plan. The first step usually includes a CT scan performed by a radiologist to find the exact area that needs to be targeted with x-rays. Next, the therapist uses a special machine that emits radiation called a Linear Accelerator. They use this machine during a treatment called external beam therapy. During this process, the Linear Accelerator will project x-rays at targeted cancer cells or tumors. Another therapist will be in a different room monitoring the patient’s viral signs until the procedure is over. The external therapy l...
Cancer develops when cells in a part of the body begin to grow out of
The energy in ionizing radiation can cause chemical changes in the the cells that can lead to damaging them. Most of the cells can either permanently or temporarily become abnormal or they can just die. Radiation can cause cancer by damaging the DNA in the body. The damage of the cells can also depend on how long the organs are exposed (environmental protection agency, 2017, unknown). If someone has many exposures at one time that radiation in the body keeps adding on. As well as if its only a little bit of exposure in on day and years later you get exposed again it keeps adding on the radiation will never leave the body. Having radiation in your body doesn’t affect you right away but as you get older it starts to show and you feel it. Chronic exposure is when someone is exposed many time for long periods. When this happens the type of effects it will carry is having harmful generic change, cancer, tumors, and even cataracts. Partial health effects can also depend on if it was internal or external exposure. Internal exposure is when either by drinking, breathing, eating and even an injection cause radiation to get inside your body. External exposure is when taking an x-ray out of your body and letting it go through letting all the energy go as it goes in (environmental protection agency, 2017, unknown). In the dental world radiation gets into the patients when we take x-rays on there teeth. In order to avoid to much radiation on them we put a lead apron on them and make sure to cover their thyroid which is the most common way of getting cancer when taking an x-ray. When we take the x-ray we stand behind a wall at least 6 feet away to avoid ourself from getting
However, if the bone involved is deep within the body tissues, then a lump cannot be noticed. If the bone cancer involves a joint, then the swelling and redness may make using the joint difficult. IF the affected joint is in the leg, it can cause a limp and if it involves spine, it may press on nerves, causing numbness and tingling in the limbs. If the bones of the neck is affected with cancer then, a lump may develop on the back of the throat that can lead to trouble swallowing or breathing trouble.