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Discuss the relevance of evolutionary theory to biomedical science
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Discuss the relevance of Evolutionary theory in Biomedical Science.
Evolution is still nevertheless one of the most largely discussed topics in modern society. The theory of evolution was first proposed by Charles Darwin (1990) and is described as process by which all biotic creatures have developed and advanced from primitive organisms through changes occurring over time. The relevance of this fundamental theory is witnessed throughout the many disciplines of the pathology department in subject area biomedical science. Biomedical science consists of seven major disciplines; haematology, transfusion science, clinical chemistry, histology, virology, cytology, immunology and medical microbiology. However, significance of evolutionary theory had a drastic impact on mostly haematology and some virology.
This branch of biomedical science has a significant effect on the society of the modern world. The science of haematology significantly influences the understanding of several diseases due to the nature of the blood. This is clearly visible during identification of diseases such as leukaemia, anaemia and abnormalities of blood coagulation that are completed through haematological tests. Some of the haematological tests done in biomedical science industry include of Fluorescence in Situ Hybridization (FISH), Karyotype Test and Serum Ferritin.
The study of structure, function and pathological disorders in blood is called “Haematology”. Blood consists of 55% plasma and 45% blood cells. Plasma is a mixture of 7% protein, 91% water and 2% other solutes. The types of proteins present in blood are albumin, globulin, and fibrinogen. Other remaining solutes consist of ions, nutrients, gases and respiratory substances and waste products. On th...
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...A as means of precaution and confirmation whether the pancreas are performing in standard conditions. Also, the following tests are ordered to conclude if pancreatic enzyme supplementation is required.
However, individuals with blood type B
Moreover, another molecule present in blood that fights foreign substances is antibodies. The structure of antibodies consists of four polypeptide chains. Two identical heavy chains and two identical short chains and arranged in a three structural unit also known as Y shaped molecule.
Thus the vital discovery of the varieties and similarities of the blood groups provided a possible gateway for many other medical procedures in this 21st century through biomedical science. For example, blood transfusions have become a routine procedure. Consequently, many other medical practises such as surgery, blood banks, and transplants.
In this experiment, we determined the isotonic and hemolytic molar concentrations of non-penetrating moles for sheep red blood cells and measured the absorbance levels from each concentration. The results concluded that as the concentration increased the absorbance reading increased as well. A higher absorbance signifies higher amounts of intact RBCs. The isotonic molar concentration for NaCl and glucose is 0.3 M. The hemolysis molar concentration for NaCl and glucose is 0.05 M. Adding red blood cells to an isotonic solution, there will be no isotonic pressure and no net movement. The isotonic solution leaves the red blood cells intact. RBC contain hemoglobin which absorbs light, hemoglobin falls to the bottom of the tube and no light is absorbed. Determining the isotonic concentration of NaCl and glucose by finding the lowest molar concentration. In contrast to isotonic molar concentration, hemolysis can be determined by finding the
P3 – Describe the investigations that are carried out to enable the diagnosis of these physiological disorders
Darwinian medicine is a radical approach that considers why evolution has not “freed” humans from disease. Traditional medicine, for example, would examine who contracted a cold, why, and how to treat the symptoms. Evolutionary medicine examines the interplay between virulence, transmission, natural selection, and evolution in an attempt to understand why anyone would catch a cold.
Explain what happened to the blood cells at the various levels of concentration. Be sure to refer to the solutions as being hypotonic, hypertonic and isotonic.
Blood Plasma: The blood plasma makes about 55% of the human blood and 45% is made of cells. The pH and salt concentration of the blood plasma is controlled by the kidneys. The blood plasma contains hormones and salts, it also excretory product such as carbon dioxide, urea and uric acid. Food molecules such as glucose, fatty acids and amino acid dissolves in the blood plasma. Most importantly, blood plasma contains plasma proteins which are essen...
Rodak, B. F., Fritsma, g. A., & Doig, K. (2007). Hematology: Clinical Principles and applications. St. louis: Saunders Elsevier.
The interest in studying Rhesus disease stems from an aspiration to understand blood and its’ components at a cellular level. In order to recognize what factors lead to this disease and what components of the cell can be used as indicators/markers to diagnose it, one must have a general idea of the concepts involved in cellular processes. This paper will focus on the causes of hemolytic disease, including natural and/or surgical & medicinal occurrences that cause isoimmunization; how antigens and antibodies are involved, and the effectiveness of Rh immunoglobulin will also be considered.
Each red blood cell in the human body contains about 280 million hemoglobin molecules. Hemoglobin is the most important component of red blood cells. Red blood cells are composed of a protein (globulin) and a molecule (heme), which binds to iron. Normal hemoglobin causes regular oxygen and carbon dioxide exchange. In the lungs, the heme, which binds to iron, component takes up oxygen and releases carbon dioxide. The red blood cells carry the oxygen to the body's tissues, where ...
Biological evolution is descent with modification. Theories of evolution have their roots in early Greek and Roman culture. Before seventh century B.C.E., people believed that supernatural forces were responsible for life. Philosophers Plato and Aristotle argued against this doctrine. They used logic to explain the origins of life. It was commonly accepted that the earth was only a few thousand years old, species were immutable, and that life is arranged linearly. In the seventh century, naturalist John Ray used the term “species” as the basic unit of classification. In the eighteenth century, Carolus Linnaeus created a hierarchical classification system for organizing species based on resemblance using phylogenetic trees. In 1809, French theorist Jean-Baptiste Lamarck published his theory of inheritance of acquired traits. In 1830, Charles Lyell introduced uniformitarianism as the mechanism for evolution; the theory that states that geologic change is relatively constant. In the mid-nineteenth century, Alfred Wallace and Charles Darwin both individually conceived natural selection as the mechanism for evolution. Darwin received credit for the theory of natural selection because he published his book, On the Origin of Species, before Wallace. In 1865, Gregor Mendel is the founder of modern genetics through his work with pea plant crosses. To this day, the work of Mendel and Darwin are widely accepted.
To diagnose RMS, patients must go through lab studies, genetic studies, imaging studies, and biopsy. Lab studies include complete blood count (CBC) to detect anemia or pancytopenia, liver function tests (LFTs) including LDH, AST, ALT, alkaline phosphatase, and bilirubin levels which all detect proper function of the liver, renal function tests (RFTs) including BUN and creatinine levels, urinalysis to detect hematuria, and blood electrolyte and chemistry. Genetic studies include fluorescent in situ hybridization (FISH) and reverse transcriptase when FISH is unavailable or ineffective. Imaging studies include plain radiology, CT scanning, MRI, bone scanning, ultrasonography, and
Sharing certain aspects of practice with other disciplines of pathology like clinical pathology, anatomic pathology, biochemistry, and molecular biology, molecular pathology seeks to understand and diagnose, at a molecular level, the mechanisms and origins of diseases (Harris and McCormick 2010). Through patient samples tests are carried out to measure
The study addresses how adaptation and divergence for asexual organisms can continue for generations through natural selection, even in a constant environment, and how evolutionary adaptation is reached by chance events and accumulation of mutations over time. The goal was to examine the rate of evolutionary change, repeatability of evolution, and to examine the relationship between change in phenotype and genotype. The hypothesis was that evolution has an underlying genetic component that is proven by sustained divergence and phenotypic changes held in a constant environment through a hyperbolic model. Important predictions are that genetic information must be rearranged or mutated from existing genotypes in order to produce new phenotypes and genotypes and the relationship between cell size and mean fitness is either rigid or malleable.
Evolution is a theory that argues that all organisms alive on earth today share a common ancestor. It is thought that through generations, specific changes or adaptations were established in species in order to help them survive, reproduce, and raise offspring. But how are we certain that these changes occurred? Today, there is an abundant amount of research evidence that suggests that anatomical and physiological alterations occurred to species that caused them to turn from aquatic animals to terrestrial animals, allowing them to survive different environmental conditions. The following are several gradual changes an aquatic organism must go through in order to move to land and adjust to its new terrestrial habitat: circulatory and most importantly respiratory systems must be improved, structural adaptations should be modified, development of a skeletal system to protect the body and organs, and an adjustment of the senses must also occur.
Without evolution, and the constant ever changing environment, the complexity of living organisms would not be as it is. Evolution is defined as a process that results in heritable changes in a population spread over many generations (8).Scientists believe in the theory of evolution. This belief is based on scientific evidence that corroborates the theory of evolution. In Figure 1 the pictures of the skulls depict the sequence of the evolution of Homo-sapiens. As the figure shows, man has evolved from our common ancestor that is shared by homo-sapiens. The change of diet of homo-sapiens over time has thought to contribute to the change in jaw structure and overall skull shape.
The advances in modern medical science in the near future are dependent upon the advances of methods and procedures that by today’s standards are considered to be taboo and dangerous. These methods will not only revolutionize the field of medicine but they will be the forerunners to a whole knew way to treat people. For these advances to take place several key steps need to be taken both medically and politically. In this paper I will attempt to explain what methods and procedures will be the future of modern medicine, how these methods and procedures can benefit mankind, and finally what changes will be needed in the fields of medicine and politics.