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Darwin natural selection
Effects of aging
Biological perspective on aging
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Recommended: Darwin natural selection
Senescence, usually defined as progressive loss of fertility and increasing probability of death with increasing age (Kirkwood and Austad 233), is clearly a process detrimental to an individual – and, at first glance, hard to reconcile with the process of natural selection ,which would work towards ensuring optimal survival and increasing fitness (reproductive success). It seems, at a cursory glance, that it would also work towards preventing the aging process because aging leads to increased mortality rates and decreased reproductive capability.
Historically, the first attempt to explain aging from an evolutionary perspective was proposed as the “mutation accumulation” theory, which posits that the force of natural election decreases with age, allowing the accumulation of deleterious genes with age-specific effects on mortality rate. In other words, natural selection is quite effective at eliminating alleles that have deleterious effects early in life, but late in life its force diminishes; evolution allows the accumulation of deleterious alleles by a combination of mutation pressure and genetic drift, unopposed by natural selection (Rose 363-371). This idea, as sketchy as is was unsubstantiated, was further developed into “antagonistic pleiotropy” hypothesis, which basically argues that natural selection favors alleles that have aging as a side-effect, provided they had beneficial effect during youth - they exhibit pleiotropic, or opposite effects at different calendar ages, and senescence is basically a “maladaptive byproduct of selection for survival and reproduction during youth” (Fabian and Flatt).
These theoretical insights form a basis for the evolutionary theory of senescence that explains why aging is occurring. To fur...
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...xclusive and they both can account for the occurrence of senescence. They are also not the only ones that contribute to explaining why we age – “the disposable soma theory of aging” is yet another of the concepts that can contribute to the understanding of senescence, but it is a concept based on ecological factors, and the first two theories provide groundwork for the evolutionary theory of aging.
Works Cited:
Fabian, Daniel and Flatt, Thomas. ‘The Evolution of Aging’. Nature Education Knowledge 3.10 (2011)
Kirkwood, Thomas B.L., and Steven N. Austad. 'Why Do We Age?'. Nature 408.6809 (2000): 233--238. Print.
Masoro, Edward J. Challenges of Biological Aging. New York: Springer Pub. Co., 1999. Print.
Rose, Michael R., Molly K. Burke, Parvin Shahrestani, and Laurence D. Mueller. "Evolution of ageing since Darwin." Journal of Genetics 87.4 (2008): 363-371. Print.
The aging process is defined best as a systematic deterioration of cells through repetitive division over time.
Common sense seems to dictate that we are all going to die one day. As we all get older we crave to keep our youth, and to stay young forever is the ultimate dream. The thought of a possible immortality is just an added benefit. Even though we have strived towards this goal for centuries, have we obtained advances in successfully staying young forever? In Bill Gifford’s book “Spring Chicken: Stay Young Forever (Or Die Trying)” he explores these ideas of life and aging further. In this novel, he goes on a journey to try and debunk the mysteries and questions behind the new science of aging. He gathers information from tests and scientists from around the country to discover what really works to prevent or delay aging and what is just a hopeful hoax. He helps us figure out why we age and why aging
The concept of successful aging is also termed as super aging or optimal health, coined by Rowe & Kahn in 1987. Fundamentally, successful aging in the elderly illustrates neither usual aging (a gradual decrease in biological and psychological functioning) nor pathological aging. Instead, it illustrates a form of aging connected to a reduced possibility of disability or disease, increased physical and cognitive functioning, including autonomy maintained. Aging and old age for a long time presented as dominated by negative traits and states such as sickness, depression and isolation. The aging process is not simply senescence; most people over the age of 65 are not senile, bedridden, isolated, or suicidal (Aldwin & Levenson, 1994).
I learned that the gene for telomerase is the focus for a discussion of aging and immortality. I also learned that the ethnic differences in the frequency of a particular breast cancer gene are used to describe the relationships among population genetics, prehistoric migrations, and linguistic groups. Also, the gene for the classical ABO blood group is the springboard for a discussion of genetic selection and drift. This book reveals genes that we share with all living creatures and those that are unique to our species. It describes genes that are essential to every cell and then those that seem to serve no useful purpose at all. It tells us about genes that predict disease with complete certainty and those that only tilt the scales.
“Lifestyle Changes May Lengthen Telomeres, a Measure of Cell Aging.” UCSF. University of California San Francisco. 11 February 2014. https://www.ucsf.edu/news/2013/09/108886/lifestyle-changes-may-lengthen-Telomeres-measure-cell-aging.
...nescence is result of a combination of the antagonist pleiotropy theory, mutation accumulation theory and disposable soma theory. The three evolutionary theories claim that natural selection is weak and ineffective in sustaining reproduction, growth, survival and somatic repair during the post-reproductive years causing genetic diseases in older individuals compared to younger individuals. As biological processes shut down, older individuals develop a weak immune system that can no longer fight the deleterious genes and mutations leading to death. Moreover, the evolutionary theories paved way for new research in gerontology that led to the development of new genetic theories of aging. The definite cause of genetic diseases in older individuals is yet to be determined, but all theories suggest that senescence is an inevitable process that all organisms experience.
According to Darwin and his theory on evolution, organisms are presented with nature’s challenge of environmental change. Those that possess the characteristics of adapting to such challenges are successful in leaving their genes behind and ensuring that their lineage will continue. It is natural selection, where nature can perform tiny to mass sporadic experiments on its organisms, and the results can be interesting from extinction to significant changes within a species.
In the 16th century, rumors of the Fountain of Youth had spread like wildfire. The thought of immortality, and everlasting youth had fascinated many old, and young adventurers. Most Eukaryotic organism cells are affected by a biological process known as aging. Effect of aging may include the advent of illness, disease, and ultimately death. Death, this fear of end existence had enthralled many people on the quest for prolonged longevity. Therefore, how do we extend our lifespan? Where is this “Fountain of Youth” ? Although the latter question may forever remain a lucrative theory. Perhaps the answer to prolonged longevity may reside on a little known region of a chromosomes, the telomeres.
Aging occurs at the biological, psychological and social levels. With numerous theories of aging spanning over many disciplines, no one is truly certain why we age or how we cope with it. Fortunately, our knowledge of how the body regulates or governs the rate of aging is slowly being demystifyied and we now know more about this process. Activity and disengagement are two major psychosocial theories which describe how people develop in old age.
There are a number of benefits to be found from thinking about ageing as a lifelong process and not just one that affects older people. This essay will define some of these benefits whilst backing up this reasoning with reference to the K118 material. It will then explain briefly which experiences I have had personally which have led me to responding to the question in this manner.
Finally after a few decades of work in his respective profession, the elder gets an opportunity to enjoy life in his golden years. However, in the context of Dr. James Curtsinger’s article, the ‘golden years’ refers to a species’ reproductive time. The author mentions that despite where we come from and who we may be in this life, the quality of our lives, especially after reproduction, is not as important as being able to pass on our genetic material onto the next generations. In last week’s article, it was discussed that in order to increase our reproductive success, our health would need to decline. The decline of health has more to do with having particular traits to make us more reproductively successful than it does with how long we’ve
In large part, the theory of degeneration draws its roots from Darwin and Spencer’s theories of evolution during the mid and late 1800s. Darwin proposed that animals evolved through natural selection from a more primitive ancestor, and that this evolution did not have a direction (Darwin). Meanwhile, Spencer’s theories used
SÍTAR, M.E., YANAR, K., AYDIN, S. and ÇAKATAY, U., CURRENT ASPECTS OF AGEING THEORIES AND CLASSIFICATION ACCORDING TO MECHANISMS. .
play a large part in our health and our developmental status. The role of age
Without evolution, and the constant ever changing environment, the complexity of living organisms would not be as it is. Evolution is defined as a process that results in heritable changes in a population spread over many generations (8).Scientists believe in the theory of evolution. This belief is based on scientific evidence that corroborates the theory of evolution. In Figure 1 the pictures of the skulls depict the sequence of the evolution of Homo-sapiens. As the figure shows, man has evolved from our common ancestor that is shared by homo-sapiens. The change of diet of homo-sapiens over time has thought to contribute to the change in jaw structure and overall skull shape.