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Thalidomide essay introduction
Drug standard and legislation
Thalidomide essay introduction
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the type of reporting. For example; summary statistics of reports by foreign and domestic countries, summary statistics of reports by healthcare professional and consumers, and summary statistics by manufacturer.
In the year of 1962, Kefauver-Harris drug Amendment Act was established. The act stated, all drugs has to undergo strict surveillance during clinical trials and also after drug is marketed out. The clinical trial has to provide data that proves that the drug is both safe and effective before being marketed out. This act was established after Thalidomide Tragedy that took place in 1960’s. In 1960, Thalidomide became very popular drug for sleeping just like when aspirin was first discovered. Thalidomide was marketed out to 46 countries and was sold as over-the-counter drug. During that time, the drug was said to be safe for pregnant women. An Australian Obstetrician, name Dr. William McBride starting observing elevated levels of morning sickness in pregnant women caused by the drug Thalidomide. Then, when delivering many babies with severe child defect he then realized that t...
In order to make the decision, this report measures the following qualitative and quantitative areas:
Mary Zimmerman framed that women have not had ultimate control over their own bodies and health as a fundamental assumption underlying women’s health movement. Men control and dominate a huge portion of the of decision making roles in the healthcare field, such as health related research, health policy etc. Whereas women are more seen in social positions. According to the article “The Women’s Health Movement” by Mary K. Zimmerman, the concept of medicalization is the “increasing tendency to apply medical definitions and control to phenomena not previously thought of as medical problems (Zola, 1972; Conrad and Schneider, 1980). In the 1950’s a drug called Thalidomide was created by a German company, claiming that it was safe for pregnant women. Although many women were still using this drug during this time, in 1961, reports began to surface that this drug was causing several birth defects and other health problems. The author presented the Thalidomide case as an example of medicalization by showing us the potential consequences of a style medical
Treating depressive and bipolar disorders with antidepressants remains a popular option in clinical practice. Most clinicians choose the drug or class of drugs, usually selective serotonin reuptake inhibitors, SSRI's, that is most effective and best tolerated with fewer severe side effects. These drugs are beneficial because they specifically target serotonin-based areas of the brain without affecting other neurotransmitter systems. SSRI's largely replaced tricyclic antidepressants which work by blocking the absorption (reuptake) of the neurotransmitters serotonin and norepinephrine, thereby increasing the levels of these two neurotransmitters in the brain. Tricyclic antidepressants present severe side effects and thus are usually only used when other treatments have failed. If SSRI's or tricyclics are not effective Monoamine oxidase inhibitors may be prescribed. MAOI's, enhance tyramine to increase norepinephrine and serotonin. While taking MAOI's you must abstain from foods and alcohol that contain tyramine such as, yogurt, aged cheese, and substances such as cold medications. This is because a potential toxic reaction could occur. Additionally, other antidepressants may be utilized such as Wellbutrin (bupropion) an NDRI-
...n of the research method or methods used to gather and interpret them are included. The method used to collect data is normally outlined in the article is appropriate to the topic, and allows the study to be duplicated for purposes of verification. The document relies on other sources that are listed in a bibliography or includes links to the documents themselves. The document names people and/or sources that provided non- published data used in the preparation of the topic of study.
Preventative medicine comes with the potential for making our lives both better and worse. Today the world in which we live in has faced steady medicalization of daily existence. Many factors have contributed to the rise of medicalization. For instance the loss in religion, the increase of faith in science, rationality, progress, increased prestige and the power of the medical profession. The medical profession and the expansion of medical jurisdiction were prime movers for medicalization. Medicalization has also occurred through social movements. Doctors are not the only ones involved in medicalization now, patients are active collaborators in the medicalization of their problem. Critics try to argue for or against the idea that this leads to a favorable versus a non -favorable outcome. This increased establishment and development of medicine, including technoscience, has resulted in a major threat to health. The medicalization of normal conditions, risks the creation of medical diagnoses that are widely inclusive and that hold the potential for further expansion. Many biologically normal conditions, like shortness, menopause, and infertility, are currently considered medical problems. These naturally occurring states are now regarded as undesirable and deviant. This process is referred to as medicalization. Although they are considered deviant, however, the process of medicalization also removes culpability: a person’s problems can be ascribed to a chemical imbalance rather than seen as reflecting his or her character or accomplishments. Some of the articles I will be looking into are Dumit’s “Drugs for life” as well as Healy’s “Pharmageddon” and Cassel’s “Selling Sickness” to explore if this process of overmedicalization has le...
Waking up in the morning seems to be a task that daunts us all at some point in our lives. Fighting the grogginess that continues to descend upon someone’s waking mind. What if instead of eventually going away, that feeling stayed was there every single waking minute? People who have depression often feel this way, except instead of fighting grogginess they are fighting themselves. According to Merriam Webster antidepressants are defined as “used or tending to relieve or prevent depression” (“Definition of Antidepressants” 2018). Antidepressants are one of the most common remedies for depression. If they work effectively or not is another question. Some argue that people should be allowed to take antidepressants because they boost concentration,
The Russell-Uflad Company developed the RU-486 pill in France in 1980. The women of France greatly hailed the development of this pill. It was said to be safer, easier, and more private since the pill can be taken at home, or in a doctor's office instead of a hospital. The pill has proven to be very effective and has found its way to the United States, but is only tentatively approved. Why should it not be approved if it could be an easier, more private way to have an abortion? Over half a million women in France have used the RU-486 pill and there have been very few cases reported with serious side effects. (Banwell 82) The side effects have only occurred in 4 percent of the women who have already used the pill. The side effects have been so minor that most of the women did not need medical attention.
The ways in which a woman could have an abortion were high in numbers. According to Knight (1977), woman could purchase medicines and drugs at a chemist to acquire an abortion, drugs such as quinine. There was also a number of cases of lead poisoning, as a doctor had seen 100 cases of it from 18...
Spielman, B. (1995). [Review of Women and prenatal testing]. Journal of Law, Medicine & Ethics, 23, 199-201.
Although not particularly in an integrated format, Amcor’s reports have extensive detail to the core content elements of i0ntegrated reporting. Through two reports, they address the six capitals of Integrated reporting which are Financial, Manufactured, Intellectual, Human, Social Relationship and Environmental Capitals.
Data and statistics that will likely be collected and what exhibits or tables will be produced from this data
The calamity of thalidomide is one of the worst disasters in pharmaceutical history. During a post-war era, when people were commonly experiencing insomnia, there was high demand for sedatives like thalidomide. The drug was retailed as a sleeping pill that you could never overdose on. It was even considered safe enough for pregnant women. It helped them with morning sickness. It was “the only non-barbiturate sedative known at the time” (Fintel et al.) which gave the drug tremendous allure. However, in 1962, evidence revealed that the drug caused babies to be born with malformed/missing limbs (Figure 1). This classified the drug as a teratogen. Thalidomide is composed of alpha-phthalimido-glatirimide (“Recognition of Thalidomide Defects”) and was created by a German company by the name of Chemie Grunenthal. It was originally created as an anticonvulsant drug meaning that it was originally intended to treat epileptic seizures. But early trials showed that it did not work for this but it had sedative properties. It’s most noteworthy property was that no one could
During the time period abortions were illegalized, it’s estimated that thousands of women died or suffered serious debilitating medical problems after attempting to self-induce their abortions or going to untrained practitioners through back-alley abortions who used primitive methods as well as unsanitary conditions. Once an abortion attempt was made, the hospital had to treat these women. However many of them were treated with distain. Some women are not fit to be mothers and some were just unprepared. Whatever the reason it’s the woman’s concern.
The data collected will be analysed and interpreted. The summary of the findings, suggestions and the conclusion will be given in the report.
The findings are then summarised and accordingly stated with the help of standard methodologies which are then concluded providing with the various limitations and the recommendations.