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Colon cancer research paper
Colon cancer research paper
Colon cancer research paper
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Cancer is a class of diseases characterized by uncontrollable cell growth. Colon cancer forms when cells in the large intestine grow uncontrollably. Most colon cancers come from small, benign tumors known as adenomatous polyps that form on the inner walls of the large intestine. Some of these polyps can grow and become malignant colon cancers over time if they are not removed during a colonoscopy. Colon cancer cells will invade and hurt healthy tissues that are near the tumor creating a lot of problems. After malignant tumors form, the cancerous cells can travel through the blood and lymph systems. This will allow the cells to spread to even farther parts of the body. These cells can grow in many places. The cells will invade and damage other healthy tissues throughout the body. This process is called metastasis. The result of metastasis is a more serious condition that is extremely hard to treat. Colon cancer cells do not go through apoptosis. They continue to grow and divide. Although scientists do not know the reason as to why these cells behave that way, they have found some potential risk factors. Polyps are one of these potential risk factors. Colon cancer usually comes from precancerous polyps that exist in the large intestine. Colon …show more content…
It is normal for people with colon cancer to experience no symptoms in the early stages of it, but when the cancer grows, people experience symptoms such as diarrhea, constipation, changes in stool consistency, narrow stools, rectal bleeding, blood in the stool, pain during bowel movement, continual urges to defecate, weakness, fatigue, unexplained weight loss, irritable bowel syndrome, and iron deficiency. If the cancer spreads to other parts of the body, other symptoms can be experienced in the newly affected area, but the symptoms depend on which part of the body the cancer has spread
Colon and rectal cancer develop in the digestive tract, which is also called the gastrointestinal, or GI, tract. The digestive system processes food for energy and rids the body of solid waste matter (fecal matter or stool). Colon cancer and rectal cancer have many features in common. Sometimes they are referred to together as colorectal cancer.
Colon cancer is the third most common cancer in men and women, responsible for more than 57,000 deaths in 2001 alone. Colon polyps, which can lead to colon cancer, are found in about 30-40% of people aged 60 or older- and the risks of polyps increase with age” (Lerche Davis, 2003). Most cases of colon cancer start as small adenomatous polyps. Many people experience no signs or symptoms in the early stages of colon cancer. Some signs and symptoms can include diarrhea, constipation, or any change in consistency of your stool that continues for longer than a month. Any bleeding from the rectum or blood found in the stool can also be a sign of colon cancer. Continuing abdominal pain, cramps, gas, weakness, fatigue and unexplained weight loss could all be signs of rectal cancer in the patient (Staff,
Crohn’s disease is a disease that causes inflammation, swelling, and irritation to any part of the digestive tract which is also known as the gastrointestinal tract or GI tract. The disease most commonly targets the ileum which is a part in the small intestine. The digestive tract is organs that connect your mouth to your anus and it releases hormones and enzymes for the digestion in food. The inflammation caused by the disease goes deep into the lining of the digestive tract. It creates a stricture in the small intestine which is a narrowing of the pathway that can slow the movement of food through the intestine. The stricture can then move to large intestine which can cause many problems for absorption. When the disease causes the intestine to swell it can also be very problematic because the large intestine wouldn’t be able to function properly. Crohn’s disease is considered as an inflammatory bowel disease.
I have chosen to write about the constellation Cancer (The Crab). I chose Cancer because it is one of only a handful of constellations that I am actually able to identify in the night sky. Cancer is one of the twelve Zodiac constellations; people whose birthdays fall between June 21st and July 22nd have Cancer as their sign. Cancer is the Latin word for crab, and despite the fact that the constellation looks more like a lobster then a crab, it is still referred to as a crab. The constellation is visible from the northern hemisphere from late winter to early spring.
Ulcerative colitis progresses from the rectum and moves proximally. Distal disease refers to inflammation that is limited to the rectum (proctitis) or rectum and sigmoid colon. Here it is referred to as proctosigmioditis. If the disease is more extensive it includes the left side of the colon and can cover the splenic flexure. This occurs in 40% of patients. Extensive colitis occurs up to the hepatic flexure. Pan colitis affects the whole of the colon and this can affect up to 20% of patients. Some patients with pan colitis have involvement of the terminal ileum, this is caused by an incompetent ileocaecal valve.
Cancer is the term used to describe a group of diseases consisting of hundreds of ailments and although there exists so many different types of cancer, they all begin in a similar way. The body is made up of over a trillion cells, and cancer is the uncontrolled growth of malfunctioning cells in the body (Dawson, 1996). “Normal body cells grow, divide, and die in an orderly fashion. During the early years of a person’s life, normal cells divide faster to allow the person to grow. After the person becomes an adult, most cells divide only to replace worn-out or dying cells or to repair injuries” (American Cancer Society, 2012).
Crohn’s Disease and Ulcerative Colitis are both in a category of diseases called Inflammatory Bowel Diseases. This is a classification of disease in which inflammation forms in a part of the digestive tract, known as the gastrointestinal tract or GI tract, of the patient. The immune system then treats this area of inflammation as a foreign pathogen and attacks it. The causes of both of these diseases are currently unknown to the medical world.
Cancer starts when cells in a part of the body start to grow out of control. Cancer cell growth is different from normal cell growth. Instead of dying, cancer cells continue to grow and form new, abnormal cells. Cancer cells can also invade (grow into) other tissues, something that normal cells cannot do. Growing out of control and invading other tissues are what makes a cell a cancer cell. Cells become cancer cells because of DNA (deoxyribonucleic acid) damage. DNA is in every cell and it directs all the cell’s actions. In a normal cell, when DNA gets damaged the cell either repairs the damage or the cell dies. In cancer cells, the damaged DNA is not repaired, and the cell doesn’t die like it should. Instead, the cell goes on making new cells that the body doesn’t need. These new cells all have the same abnormal DNA as the first cell does.
Colon cancer develops in the part of the gastrointestinal tract that absorbs water and minerals before waste products are disposed via the rectum. In women endometrial cancer is related to colon cancer. This type of cancer is the second leading cause of death due to cancer in the United States. Over one-hundred fifty thousand individuals will be diagnosed this year and this cancer will probably be responsible for about 47,900 deaths in 1999 (http://www.cancer.org). Most colon cancers are adenocarcinomas that develop from the glandular cells. Ninety percent of all colon cancer cases will develop in individuals after 50 years of age. Ninety percent of all tumors arise from polyps that are commonly found in people older than 50. Prevention includes regular exercise and a diet high in fiber. The most important risk factor is age. Medical screening includes a yearly blood occult test after age 50 and a colonoscopy every 3 years after age 50. Regular screening detects polyps that have become precancerous. If regular screening is not done, the cancer is not detected until blood is found in the...
Some symptoms for colon cancer are, change in your bowel habits, including diarrhea or constipation, rectum bleeding or blood in your stool, constant abdominal discomfort, such as cramps, gas or pain, a feeling that your bowel doesn't empty completely, weakness or tiredness, and or unexplained weight loss. Many people with colon cancer experience no signs of sickness in the early stages of the disease. When signs of sickness appear, they'll likely differ, depending on the cancer's size and location in the large intestine.
Ulcerative colitis, or UC, is a chronic gastrointestinal disease that causes inflammation and ulcers in the lining of the large intestine. It causes ulcers in the colon and rectum. Ulcerative colitis is one of two forms of inflammatory bowel disease. In UC, the inflammation from the ulcers breaks down the lining of the colon and causes bleeding and discomfort in the abdomen.
Cancer develops when cells in a part of the body begin to grow out of
Everyone is born with certain genetic mutations that make the them more likely to develop cancer in a later time in life. Though they might have a genetic feature, cancer will not develop unless triggered by environmental factors such as air and water pollution. As a matter of fact, my grandfather started smoking alongside consuming heavy amounts of alcohol around the age of 15, smoking and heavy alcohol intake have been considered as one of the potential causes of colon
Cancer is a disease that affects human somatic cells. It causes the cells to divide uncontrollably and form masses known as tumors. There are two different types of cancer tumors. Some tumors are benign and other tumors are malignant. Benign tumors look similar to the tissues that they came from and develop slowly. The tumor remains in the same area that the tumor originated in. Malignant tumors are formed from cells that do not resemble the tissue that they came from. They vary in shape and size. This enables pieces of the tumor to break off and spread to other places in the body. Over the past few decades cancer has become a very prominent disease. There are many different types of cancer and many different causes for the the disease. Most cancers are because of a genetic mutation. The most common type occur when a cell is dividing. Proto-oncogenes, which are alleles in a normal cells, mutate to form oncogenes. These oncogenes cause cancer because they do not allow the cells to self destruct or become epistatic. There have been several research projects which have been testing epistatis.
Tumors are formed by the alteration of the body’s own cells. This can be caused by environmental factors such as radiation, like UV exposure, chemicals or viruses 1. These can disrupt genes that control growth and cause an increase in cell division and proliferation. Proto-oncogenes are those genes that control normal but essential cell processes that keep cell growth and death in check. Two important categories are apoptosis genes, which regulate cell death, and tumor suppressor genes, which decrease cell propagation 1 . If these genes were mutated to the point where they cannot produce a functioning protein, cell division would continue far past what it was supposed to and unhealthy cells would be allowed to live and continue to multiply. This is what creates a malignant tumor. Certain conditions in the body can also promote the growth of cancer cells. One of these is a deficiency of natural killer (NK) cells, which are able to kill cancer cells by creating a pore in the cell membrane with perforin and releasing granzymes into the cell. Low levels of perforin allow for tumor growth 1. Chronic inflammation can also ...