Drugs affect your brain and in turn can alter your moods and behavior. Drugs are chemicals that tap into our brain’s communication system and disrupt the way nerve cells receive, send and process information. Drugs interfere with the exchange of information in the brain producing changes that promote repeated drug use. Drugs can imitate the brain’s natural chemical messengers, or they over stimulate the reward circuit of our brain.
The brain becomes accustomed to the chemical changes caused by the chemical changes caused by the substance. It begins to alter its normal production and starts releasing neurotransmitters. The user begins to lose control and has difficulty limiting their drug intake; the need to consume the substance becomes more compulsive because it has affected the region of the brain that controls impulse, behavior, and craving.
Repeated drug use over time changes the brain structure, and functions in long-lasting and fundamental ways. For example, in marijuana or heroin, they have similar structure to the chemical messengers called neurotransmitters (naturally produce by the brain). So because of this similarity the drugs are able to fool the brain receptors and active nerve cells to send abnormal messages.
When using a drug like cocaine it causes the nerve cells to release an abnormal large amount of natural neurotransmitters and also prevents the normal recycling of brain chemicals which are needed to shut off the signal between neurons. Such disruption produces an amplified message that disrupts the normal communication patterns in the brain.
4. Explain how altered neurotransmission causes some people to become dependent on chemicals.
6. Explain what addiction is and discuss why there is no one definiti...
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...ts the amount of dopamine receptors that are available, which in return diminishes the functions of the reward circuit. They are compelled to abuse drugs to bring their dopamine function back up to normal, which inquires a larger amount to achieve the normal dopamine high (this can be defined as tolerance). There are many changes in neurotransmitters other than dopamine. Long-term drug abuse causes changes in other parts of our brain chemical system, for example the glutamate which is a neurotransmitter that influences the ability to learn and again it influences the reward circuit. When the optimal concentration is altered by the drug abuse the brain tries to compensate which can cause impairment in cognitive functions. One must remember that changes areas of the brain that are critical such as our judgment, memory, learning, behavior control, and decision making.
Cocaine (C17H21NO4) comes from the leaf of an Erythroxylon coca bush. It is a drug that effects the central nervous system. It causes feelings of euphoria, pleasure, increased energy and alertness. People under the influence of cocaine often do not feel the need for food or sleep. They also feel energetic and may talk a lot. However, depending on factors such as environment, dosage, and the manner in which the drug is taken, cocaine can have adverse effects such as violent, erratic behavior, dizziness, paranoia, insomnia, convulsions, and heart failure to name a few. Long- term effects of cocaine include, but are not limited to strokes, heart attacks, seizures, loss of memory, and decrease in learning capability (1).
The brain is the most complicated part of the human body. I will begin explaining certain parts and their functions. In doing this to I hope to give a better understand of our brain while implicating the possibilities of chemical induced complications “The brain with its 15 billion neurons and nerve cells operates using chemical and electrical messages: (Swanson, 1975).1 This is how we perceive our senses. Differences in the way our brain translates these messages can impair perceptions. Hallucinogens prevent the brain from receiving all of these messages in order. All of the information that we receive is through millions of transactions of neurons, like a computer, marijuana alters these transactions .
The brain controls pretty much everything you do, even while asleep. When drugs enter the brain, the substance can disturb the organ and change how the brain performs its duties to function. These changes are what lead to a continuous yearning for drugs or addiction. The signals a drug sends to the brain get confused with that of a euphoric chemical called dopamine, which makes you feel good. After repeated use of drugs the brain in most cases becomes damaged and irreparable. Adolescents are more prone to addiction due to the fact that their brains are not yet fully developed. The lack of maturity of the brain give health specialist the theory that drug use at an older age will reduce the chances of addiction.
The most commonly abused substances are Nicotine, Inhalants, Alcohol, Cocaine, Amphetamines, Prescription medications, Heroin, Ecstasy and Marijuana. 1a(National Institute on Drug Abuse, 2011) Initially, a person may find themselves using substances voluntarily and with confidence that they will be able to dictate their personal use. However, over the period of time that drug use is repeated, changes are taking place throughout the brain, whether it is functionally or structurally. Drugs contain chemicals that enter the communication system of the brain and disturb the way in which nerve cells would typically send, receive, and process information. The chemicals within these drugs will cause a disruption to the communication system by either imitating the brain’s natural chemical messengers or by over-stimulating the brains “reward system” by sending mass amounts of dopamine. As an individual prolongs his or her use of these substances, they may develop an addiction.
There are many biological factors that are involved with the addicted brain. "The addicted brain is distinctly different from the nonaddicted brain, as manifested by changes in brain metabolic activity, receptor availability, gene expression, and responsiveness to environmental cues." (2) In the brain, there are many changes that take place when drugs enter a person's blood stream. The pathway in the brain that the drugs take is first to the ventral tegmentum to the nucleus accumbens, and the drugs also go to the limbic system and the orbitofrontal cortex, which is called the mesolimbic reward system. The activation of this reward system seems to be the common element in what hooks drug users on drugs (2).
Dopamine is a reward chemical in the brain which rewards us every time we do something positive. Addiction comes from that chemical and can be created from various activities. Someone might enjoy jumping off a cliff, eating food, taking drugs or even play video games. Every time your brain enjoys something, dopamine is release and you start feeling good. The reason drug addiction is more complex, your brain will create more dopamine the more drugs you take. Eventually, your body will fight off the foreign product and dopamine will be created in too high dosage. Your body will become addicted to the dopamine, not the drug as previously thought by doctors.
Development is a never ending cycle in life. Each person begins to develop from conception until passing away. Now, while most people think that development starts after birth that is incorrect. Development starts as soon as the baby is conceived. Everything that a woman carrying a baby does or takes place in will translate into the baby. The baby shares a blood flow with the mother. Drugs, even legal drugs, will go into the mother’s blood stream which will then go into the baby’s blood stream. The “maternal blood flows through the uterine arteries to the spaces housing the placenta, and it returns through the uterine vein to the maternal circulation” (Santrock, 2012, p. 80). This means that anything that enters into the blood stream will also affect the baby. Each type of drug is under a certain category. Psychoactive drugs are drugs that are constantly being studier. According to Santrock (2012), psychoactive drugs are drugs that act on the nervous system to alter states of consciousness, modify perception, and change moods. (p.83). They come in three categories: stimulants, depressants, and hallucinogens. Stimulants include caffeine, cocaine, methamphetamine and nicotine. Some people say that pregnant woman do not know what taking these into their system is doing to their baby. Stimulants are becoming more popular and there effects need to be studied and known. Each stimulant affects the baby in short-term and long-term.
The fact that addiction is a brain disorder is a new detail that I learnt from the HBO video. As pointed out by Dr. Volkow, addiction as a brain disease renders the addicts unable to control themselves in relation to curbing their addiction problem. In conceptualizing addiction as a brain disease, Volkow illustrates this standpoint with the fact that the brain has a “natural reward system” that facilitates the learning of “behaviors that are necessary for survival” (NIDA 2006). Learning that the abused drugs take over this system – the dopamine system of the brain - was pivotal in finally grasping the rationale behind referring to addiction as a brain disorder. The brain with time becomes dependent on the abused drugs. This arises from the fact that natural rewards no longer have the capability to produce “normal levels of dopamine or pleasure” (NIDA 2006). As time goes on, the continued intake of drugs subsequently makes the addict lose all control over their use and dependen...
Chronic addiction affects parts of the brain negatively, which leads to memory loss, poor decision-making, poor judgments, and immoral behaviors. These effects on the brain from drugs are long-lasting.
Cocaine and the Nervous System. [online] Available at: http://serendip.bryanmawr.edu/exchange.node/1739 [Accessed: 2 Oct 2013]. Donaghy, M. 2005. "The Species of Neurology.
Many people that have smoked marijuana also try other drugs to get another type of high. Cocaine is a powerful stimulant that effects the brain directly. This powerful drug takes effect in very small doses by making a person feel more alert or energetic. Though people may think the drug helps them perform tasks faster with fewer complications, it also carries a list of effects. Some include constricted blood vessels, dilated pupils, high temperature, high heart rate, and bizarre behavior. Some...
Nearly all drugs of abuse increase dopamine release. Dopamine is an important neurotransmitter in drug abuse and addiction. Dopamine plays a role in reward-motivated behaviors, motor control and important hormones. It’s known as the “feel good hormone” which is why people abuse drugs that increase the release of dopamine. Since life is unpredictable, our brains have evolved the ability to remodel themselves in response to our experiences.
Abuse can cause countless medical problems to the body. A person who is addicted will continue to stimulate themselves regardless if they are aware of the negative chain reactions. Once addicted, it becomes difficult to stop due to how the body has become dependent. Health will be harmed the more a stimulant is used. Health effects include: cardiovascular disease, strokes, cancer, HIV/AIDS, hepatitis, lung disease, mental disease, birth defects. Mental health is what keeps a person in the right mind to make better decisions and have better control in life. Drugs have the ability to change mood and behavior. If drugs have affected the brain already, the desire increases which changes mental health. Some may not realize that they have been affected their health negatively. “A person who abuses drugs may not realize they have a problem until pronounced effects of drug abuse are seen, often physically. While drug abuse effects on the body vary depending on the drug used, all drug abuse negatively impacts one 's health (Addictions Community). Since drugs create many health issues, treatment is not a simple task. Treatments are hard to obtain and addictions often go
Drugs are chemicals that change the way a person's body or mind works. Drugs are not good for health as they have many side effects and damage our brain, heart and other important organs. Drug is a depressant that slows down the functions of the central nervous system and makes us less aware of the events around us. I...
The addict becomes dependent on the drug. The addict uses it, despite having full knowledge of its harmful effects on health. It is considered a brain disease because it changes the structure and functioning of the brain.There is an uncontrollable desire or craving to consume the drug. Addicted people often engage in compulsive behavior to obtain the drugs. The addicts find if impossible to control the drug intake. In case of drug abuse, people start taking drugs in larger doses than the recommended doses. The addict is not able to discharge his/her day-to-day responsibilities in an efficient manner. It effects both the physical and mental health of the addict. Very often, addicts witness extreme changes in body weight. Very often, the addict stops socializing.Sometimes, drug addiction is also referred to as drug dependency since the addict develops dependency or addiction for a particular