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Causes of cancer essay
Many causes of cancer
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This is mostly caused by that every cancer is caused by a different set of gene mutations. Genes consist of a sequence of DNA, and each sequence is a set of chemical bases called nucleotides that are arranged in a very specific order. Together, they tell the cell how to manufacture proteins, and we are mostly just made up of proteins - so that’s how we build ourselves. Mutations change those instructions, and that’s where things start to go wrong. Now, we know by this point that cancers usually come from mutations of two kinds of genes, called oncogenes and tumor suppressors. An oncogene starts out as just a normal gene that codes for proteins that signal the cell to grow. And normally, they just spend a lot of their time inactive, because growth is generally good, but cells …show more content…
There’s a serious problem, though. One study compared the results of the Cancer Genome Project and the Cancer Cell Line Encyclopedia, and it found that they came to different conclusions alarmingly often. When the two different groups of researchers treated the same cancer cells with the same drugs in a lab, they got different results. Even though the cells they used were more or less identical, they would sometimes respond differently to the exact same drugs. And even when the two projects agreed that a drug could treat a certain kind of cancer, they disagreed about what dose was needed to be effective. So, we won’t be able to count on personalized medicine to work until scientists come up with more effective ways to test these drugs, and figure out how to use them in people. So there are still some things to work out, but it’s a hopeful lead we have in the fight against cancer. We haven’t found one cure for cancer yet, but that’s kind of a question wrongly asked; there is no cancer to cure -- there are lots of cancers we need to
Pharmaceuticals have examined and found to ”work by changing the biological functions of the target cells in the body through chemical agents“ (Doweiko, 2015, p. 16). ”Many people in the past have thought that drugs that
Cancer has been an active concern in our society for the past couple decades, since we truly discovered the nature of cancer and the potency it brings along with it. However, it was not until the mid-20th century that scientists were beginning to truly understand the origin of cancer. Scientists dating back all the way to the Renaissance, when they first began performing autopsies to learn more about the human body and form, noticed abnormalities but it never clicked that it was something much worse than it seemed. Research has continued since then, and it has continued to thrive even to this day. When James Watson and Francis Crick discovered DNA and it’s chemical structure in 1962, it opened up doors that even they could not expect. With the understanding of DNA and how it affected the way we look at life, came the beginning of the understanding of mutated DNA (which is a cause of the growth of cancerous cells). In this past century, researching scientists discovered that cancer is linked with the DNA that resides in a cell’s nucleus. By ways of damage to the cells via chemicals or radiation, or even introduction of a new DNA, the cancerous cells begin to form and duplicate. We are learning more and more about cancer and how to fight it, but we still have much more to learn.
Cancer is the term used to describe a group of diseases consisting of hundreds of ailments and although there exists so many different types of cancer, they all begin in a similar way. The body is made up of over a trillion cells, and cancer is the uncontrolled growth of malfunctioning cells in the body (Dawson, 1996). “Normal body cells grow, divide, and die in an orderly fashion. During the early years of a person’s life, normal cells divide faster to allow the person to grow. After the person becomes an adult, most cells divide only to replace worn-out or dying cells or to repair injuries” (American Cancer Society, 2012).
The cancer cells from gene-mutation. Scientists now know some of the risk factors for lung cancer can cause certain changes in the DNA of lung cells. These changes can lead to not normal cell growth and, sometimes, cancer. DNA is the chemical in each of our cells that makes up our genes and how our cells function. People usually look like their parents because they are the source of our DNA. But DNA affects more than how we look; it also can affect our risk for developing certain diseases, including some kinds of cancer like lung cancer etc…Some people inherit DNA mutation from their parents that greatly increase their risk for developing certain cancers.
Chemotherapy drugs are more dangerous than other drugs because of their narrow therapeutic index. What is therapeutic index you ask? It is the ratio between a toxic dose and a therapeutic dose of a drug so any medication error with chemotherapy drugs could be a fatal one. Chemotherapy drugs can be very toxic even at the prescribed therapeutic level recommended by the physician. The findings in this article shows that the patient themselves are the first line of defense in spotting errors in medications they receive because they obs...
Cancer starts when cells in a part of the body start to grow out of control. Cancer cell growth is different from normal cell growth. Instead of dying, cancer cells continue to grow and form new, abnormal cells. Cancer cells can also invade (grow into) other tissues, something that normal cells cannot do. Growing out of control and invading other tissues are what makes a cell a cancer cell. Cells become cancer cells because of DNA (deoxyribonucleic acid) damage. DNA is in every cell and it directs all the cell’s actions. In a normal cell, when DNA gets damaged the cell either repairs the damage or the cell dies. In cancer cells, the damaged DNA is not repaired, and the cell doesn’t die like it should. Instead, the cell goes on making new cells that the body doesn’t need. These new cells all have the same abnormal DNA as the first cell does.
The cell cycle is the process by which cells progress and divide. In normal cells, the cell cycle is controlled by a complex series of signaling pathways by which a cell grows, replicates it’s DNA and divides, these are called proto-oncogenes. A proto-oncogene is a normal gene that could become an oncogene due to mutations. This process has mechanisms to ensure that errors are corrected, if they are not, the cells commit suicide (apoptosis). This process is tightly regulated by the genes within a cell’s nucleus. In cancer, as a result of genetic mutations, this process malfunctions, resulting in uncontrolled cell proliferation. Mutations in proto-oncogene or in a tumour suppressor gene allow a cancerous cell to grow and divide without the normal control imposed by the cell cycle. A change in the DNA sequence of the proto-oncogene gives rise to an oncogene, which
Cancer is a condition in the body when there is uncontrolled growth of abnormal cells that evolve into tumors. Fatty food, smoking, and drinking all affect the chances of developing cancer. Treatments for cancer include, but are not limited to, Surgery, radiation, and chemotherapy. Anyone can become a victim of cancer, but we can decrease our chances of getting cancer by being more informed on the disease and how to prevent it.
Cancer has become the one of the most feared things for human beings. The various type of cancer have been discovered and there are still a lot of it that undiscoverable. Cancer is a complex disease that have a group of disease. The cancer itself cannot be describe by words. The causes of this cancer is still not being able to be discovered fully. There are only minor factor that can lead to this disease. The carcinogens are believed to be one of the causes that lead to cancer such as asbestos, radon gas, tobacco, PVC and much more from our chemical industries. The environment especially near to the industrial that produce chemical waste can be one of the causes lead to cancer. Cancer also have relation with our age, lifestyle, and diet and also can be genetically inherited. It is believed that older people have higher tendency to get cancer than younger people. Our lifestyle and diet also plays a role causing a cancer by our daily life routine. Smoking tobacco and eating unconsciously (still in research) can also increase the possibility to get cancer especially lung cancer that cause by smoking tobacco. There are several cases, cancer were inherited from their parents. Various type of viruses such as HIV, HPV, EBV and many more virus has a high capabilities to increase the chance a patient to get a cancer because these viruses lower their body immunity to disease.
Breast Cancer, as well as other forms of cancer, scientists do know how it occurs, but they do not know an exact cause. There are some genes in our body called oncogenes, genes that have potential to cause cancer, that increases the speed of cell division while other genes such as tumor suppressors, cause the cells to die at the correct time. Mutations that occur in the DNA, which “turn on” the oncogenes or “turn off” tumor suppressor genes, will cause some of the cells to be cancerous in the breast("American Cancer Society"). Also, Breast Cancer can be increased by inherited gene mutations and acquired gene mutations. The risk of Breast Cancer can be increased dramatically, through the inheritance from parent to offspring, if a mutation occurs. For example, if a suppressor gene, such as BRCA, forms a mutation, then it is likely to be passed to future generations. This gene no longer suppresses abnormal growth, therefore there is a higher chance of cancer being developed. Even though Breast Cancer can be inherited it is more likely to be acquired through one breast cell. The acquired mutations could be a result of of radiation or cancer-causing chemicals. ...
All cancer has a genetic basis. It is triggered by mutations in the genes of a cell which then cause the cell to abnormally reproduce. Many of these gene changes are caused by random mutations when the cell is dividing. It only takes one cell mutating to cause cancer. There are no symptoms for the beginning of cancer and only five to ten percent of all cancers are caused by parents passing down genetic mutations to their children. The remaining are caused by environmental changes (Douglas).
We now can find what specific cancer a patient has and where, and give them a variety of treatment options such as surgery, chemotherapy, radiation, and several other types of treatment including experimental drugs. But there is no 100% guarantee that these treatments work. Ancient physicians and surgeons knew that cancer usually came back after it was removed surgically and recognized that there was no cure once the cancer had spread, and thought that intervention may be more harmful that no treatment at all. Some people today still think of cancer as incurable and wait until the last minute to go to the doctor. Galen was a 2nd- century Greek doctor that claimed a breast cancer tumor could be completely removed if it was caught at an early enough
Over the past few decades, cancer has become a very prominent disease. There are many different types of cancer and many different causes of the the disease. Most cancers are caused by a genetic mutation. The most common type occurs when a cell is divided. Proto-oncogenes, which are alleles in normal cells, mutate to form oncogenes.
Cancer is the uncontrolled growth of abnormal cells in the body. Tumors are then created and interfering with the digestive, nervous and circulatory systems. It is one of the most leading causes of death, reaching at about 8.2 million deaths in 2012. It is expected that cancer will rise from 14 million to 22 million within the next 2 decades. With over 100 cancer research centers in the United States studying how to treat this disease, people need to understand the importance of donating also with the awareness of signs and symptoms in the early stages. But, what are we doing about it? Do we have the technology to finally be able to put this deadly disease to an end?
Tumors are formed by the alteration of the body’s own cells. This can be caused by environmental factors such as radiation, like UV exposure, chemicals or viruses 1. These can disrupt genes that control growth and cause an increase in cell division and proliferation. Proto-oncogenes are those genes that control normal but essential cell processes that keep cell growth and death in check. Two important categories are apoptosis genes, which regulate cell death, and tumor suppressor genes, which decrease cell propagation 1 . If these genes were mutated to the point where they cannot produce a functioning protein, cell division would continue far past what it was supposed to and unhealthy cells would be allowed to live and continue to multiply. This is what creates a malignant tumor. Certain conditions in the body can also promote the growth of cancer cells. One of these is a deficiency of natural killer (NK) cells, which are able to kill cancer cells by creating a pore in the cell membrane with perforin and releasing granzymes into the cell. Low levels of perforin allow for tumor growth 1. Chronic inflammation can also ...