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The cellular basis of cancer
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Cancer
Cancer or cancer cells are the cells that have lost the normal control that body are able to exert on old cells. In our body, we have billions of cells, and they have different function. It is a very complicated process under incredible control. If something goes wrong, and that control is lost, the cell escaped the control mechanisms.They continue to grow and spread, and that is when we call it cancer. Those cells together we would call it tumor. Specifically, cancer is a malignant tumor. We call it malignant is because not only because it could invade to the adjacent organs, but also because unfortunately cancer can spread to other tissues, and that can be life threatening.
Cancer can occur anywhere in the body because there are
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There are several things that are very relevant. The stage of the cancer, which is the location of the cancer. You say its a particular kind of a cancer, how much cancer is present, has it spread? Is it in lymph nodes? has it spread to other organs of the body? Cancer treatment is very complex, and part of the reason is because cancer is the constellation of over 200 different deceases. They have common characteristics, but they are all very different from each other. In addition to that, cancer itself is not homogeneous. There might be numerous slight variations in cancer cells. After certain period of treatment, patient might find that 70% of the cancer tissues are shrunk, but there is still 30% of cancer tissues left and does not go away. That might be because this 30% of cancer cells belong to a different subtype of that cancer, which would require a different kind of …show more content…
These signals are interpreted in nucleus, and the cell reproduce its genetic information, and divide into two identical daughter cells through a process called mitosis. Cancer cells do not obey this rule, and will divide even when they do not receive the proper signal. In addition to the signal that normal cells receive that telling them to divide, they are also told when to stop dividing. This prevent too many cells from being made. In face, this cell division process is a highly ordered process. This is a critical issue in cancer, because cancer cells do not obey or require normal signals for division. This could lead to the formation of mass of cells that piles up that may form a tumor. Also different from nomad cells is the ability of cancer cells to divide indefinitely. A important point about cells is that no matter what their job is in a body, they all have the same general structure that they all have different kinds of organelles that play different important functions for the cell. Of particularly important for cancer is the organelle known as the nucleus. The nucleus contains the blueprint of information for each and one of us just as a manual would contain the instruction for a chair. Specifically, this information is contained in the chromosomes that reside in the nucleus. Individual unit of informations are called genes. At a chemical level, genes are made of
Breast cancer has always been a common thread among the women of my family; especially on my mother’s side, including my Grandmother whom passed away due to this disease before I could ever meet her. More so, my mother was gravely affected by this disease early in my life. Thankfully, she was able to stop the cancer from spreading; the doctors were able to find the cancerous cells and remove them. Due to this grave, but powerful impact on my life, I have been determined to becoming a biomedical scientist to assist on the research and treatment of this deadly disease. Although this acts as my principal driver, to study in this field, I have also been intrigued and driven by the idea that I could aid lower setting regions to receive health benefits using studies in translational medicine and
..., while a cell undergoes cell cycle, when a cell comes in contact with another cell, it stops reproducing. However, cancer cells continue to duplicate repeatedly until there is a mass of cells or a tumor to form (see figure 9). Lastly, in cell division when there is a mutation or abnormality in the DNA, a normal cell stops dividing. However, a cancerous cell will continue to duplicate and form mutations (“Cell Biology and Cancer”). Also, cancer cells are harmful because they grow and duplicate with complete disregard to the functions and limitations of the body (see figure 10). Also, cancerous cells have the ability to spread through metastasis throughout parts of the body through the bloodstream. In terms of similar behavior to that of normal cells, cancerous cells also duplicate, but at a very different rate ("Cancer Cells vs. Normal Cells: What's Different?").
According to Essentials of Human Disease and Conditions textbook, “The most important prognostic factors are age at diagnosis, size of the primary tumor, and the presence of tissue invasion or metastases. (American Cancer Society, 2012)
“The word 'leukemia' is a very frightening word. In many instances, it's a killer and it's something that you have to deal with in a very serious and determined way if you're going to beat it” - Kareem Abdul-Jabbar. Many people, including tons of children, fight leukemia every day trying to beat this vicious cancer. Without knowing how leukemia is exactly caused, it puts a damper on how to avoid it.
Most forms of skin cancer are found on areas of the body that experience constant exposure to sunlight. The ultraviolet rays in sunlight are one main cause of skin cancer, but artificial sources of UV rays have also been proven to be a contributing factor.
Cancer. The word by itself can conjure images of severely ill and frail people attached to IV medications and chemotherapy drugs as they cling to life in a hospital bed. Other illustrations and pictures depict unrecognizable, misshaped organs affected by abnormal cells that grow out of control, spread, and invade other parts of the body. Cancer studies show that close to one-half of all men and one-third of all women in the United States will be diagnosed with cancer during their lives. Today, millions of people are living with cancer or have had cancer. As patients are newly diagnosed with their specific type of cancer, whether it be breast, lung, prostate, skin, or blood cancer, etc., each patient has to consider what will happen with their future health care plan and who will be involved in their long journey from treatment to recovery. Once diagnosed, cancer patients become the focal point and the center of all activity in terms of care but cancer not only physically invades the patient’s body and well-being, it goes beyond the patient and significantly affects the emotional stability and support from from their loved ones and caregivers. Based on the insidious nature of cancer and typically late detection of malignant diseases, family members (either spouses, children, parents, other relatives, and friends) often become the patient's main caregiver. These caregivers, also known as informal caregivers, provide the cancer patient with the majority of the support outside of the medical facility or hospital environment and become the primary person to provide various types of assistance. They provide the physical support with bathing and assisting in activities of daily living, they become emotional ...
...of not only them but also other things. (Schulz 2005). Finally, in conclusion, gene mutations and alterations affect the body’s ability to control the rate of cell division, which therefore defines cancer the direct result of gene mutation. Cells affected by mutations are exposed to the reproduction into a tumour. Once the tumour expands in growth, more and more mutations occur in subsequent cell divisions and eventually become a dysplasia and instigates invasion into surrounding tissues. In simpler terms, the cancer is spread to other organs and parts of the body. Following this, metastasis occurs resulting in the cancer spreading through the person and/or animals blood stream and/or lymphatic systems and forms other colonies which thus secretes other harmful organelles, and also disrupts normal bodily function, and possibly leading to and eventuating in death.
Cancer occurs when abnormal cells grow out of control; the cells don't die, instead they continue to divide into other abnormal cells. These abnormal cells invade other tissues; this type of cancer is called metastatic cancer. If these abnormal cells get into the lymphs or the blood stream they spread and replace all other normal cells, eventually taking over the entire body and killing the person. These abnormal cancer cells are caused by damaged DNA due to sun exposure, cigarette smoke, lifestyle choices, or inherited damaged DNA. (12)
Healthy cells grow and divide in a way to keep your body functioning properly. But when a cell is damaged and becomes cancerous, cells continue to divide, even when new cells aren't...
Cancer has become a very common illness world wide for any age but mostly affecting adults. One can get cancer from different places in the body that is why there are so many people with cancer, because of all the different types. Cancer can affect any gender, female or male, and any age. It varies from ovarian cancer to prostate cancer, skin cancer to lukemia. Cancer has been a problem for many years yet we have not found a cure to treat and prevent cancer. If one is affected by cancer there are treatments to help take away this illness affecting their body. This essay is about a specific type of treatment for cancer, radiation therapy. There are different types of forms of particles for radiation, for example, protons and waves like x-rays and visible light. These types of radiations are grouped on how much energy they contain because it can cause different affects. A low type of energy radiation can be radio waves and heat, also known as non-ionizing radiation. Ionizing radiation has enough energy to break chemical bonds and knock electrons out of atoms, some examples of these are x-rays and ultraviolet light rays from the sun. That is why radiation is a way to treat cancer because of the strong energy it has to destroy a cancer cell, actually any cell in the body. That’s the issue with radiation therapy, is it worth the damage? It can damage any cell, wether it is healthy or cancerous, which can cause a major affect in the body later on. Although it sounds scary there are other types of treatments such as chemotherapy, targeted therapy, immunotherapy, photodynamic therapy, etc. So if radiation therapy does not sound like the best there are always other options but they do not develop the same results for radiation therapy. Rad...
Cancer has become the one of the most feared things for human beings. The various type of cancer have been discovered and there are still a lot of it that undiscoverable. Cancer is a complex disease that have a group of disease. The cancer itself cannot be describe by words. The causes of this cancer is still not being able to be discovered fully. There are only minor factor that can lead to this disease. The carcinogens are believed to be one of the causes that lead to cancer such as asbestos, radon gas, tobacco, PVC and much more from our chemical industries. The environment especially near to the industrial that produce chemical waste can be one of the causes lead to cancer. Cancer also have relation with our age, lifestyle, and diet and also can be genetically inherited. It is believed that older people have higher tendency to get cancer than younger people. Our lifestyle and diet also plays a role causing a cancer by our daily life routine. Smoking tobacco and eating unconsciously (still in research) can also increase the possibility to get cancer especially lung cancer that cause by smoking tobacco. There are several cases, cancer were inherited from their parents. Various type of viruses such as HIV, HPV, EBV and many more virus has a high capabilities to increase the chance a patient to get a cancer because these viruses lower their body immunity to disease.
While chemotherapy is beneficial at curing or helping a disease such as cancer, it can has a negative effect on a person’s body too.
By harnessing this normal cell process, scientists hope to have found an effective way to combat cancer. Cancer is a disease that affects human somatic cells. It causes the cells to divide uncontrollably and form masses known as tumors. There are two different types of cancer tumors. Some tumors are benign, and other tumors are malignant.
Tumors are formed by the alteration of the body’s own cells. This can be caused by environmental factors such as radiation, like UV exposure, chemicals or viruses 1. These can disrupt genes that control growth and cause an increase in cell division and proliferation. Proto-oncogenes are those genes that control normal but essential cell processes that keep cell growth and death in check. Two important categories are apoptosis genes, which regulate cell death, and tumor suppressor genes, which decrease cell propagation 1 . If these genes were mutated to the point where they cannot produce a functioning protein, cell division would continue far past what it was supposed to and unhealthy cells would be allowed to live and continue to multiply. This is what creates a malignant tumor. Certain conditions in the body can also promote the growth of cancer cells. One of these is a deficiency of natural killer (NK) cells, which are able to kill cancer cells by creating a pore in the cell membrane with perforin and releasing granzymes into the cell. Low levels of perforin allow for tumor growth 1. Chronic inflammation can also ...
For most, the primary fears associated with cancer are connected to the effects of treatments. If the patient is diagnosed when the cancer is still in the early stages, more than likely surgery is the appropriate treatment. However if the cancer has developed into an advanced stage, a more drastic treatment is necessary.