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Colorectal cancer
Colorectal cancer
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Recommended: Colorectal cancer
What is colon cancer?
Colon Cancer is cancer of the colon, or large intestine. Rectal cancer is cancer of the last few inches of the colon. Together, they're often referred to as colorectal cancers. Most cases of colon cancer begin as small, harmless clumps of cells called polyps. Over time some of these abnormal growths may become colon cancers. Polyps may be small and produce few, signs of sickness. Because of this, doctors recommend regular screening tests to help prevent colon cancer.
Symptoms
Some symptoms for colon cancer are, change in your bowel habits, including diarrhea or constipation, rectum bleeding or blood in your stool, constant abdominal discomfort, such as cramps, gas or pain, a feeling that your bowel doesn't empty completely, weakness or tiredness, and or unexplained weight loss. Many people with colon cancer experience no signs of sickness in the early stages of the disease. When signs of sickness appear, they'll likely differ, depending on the cancer's size and location in the large intestine.
If you notice any of these signs of colon cancer, such as blood in your stool, make an appointment with your doctor. Talk to your doctor about when you should begin screening for colon cancer. Guidelines generally recommend colon cancer screenings begin at age 50. Many doctors recommend more frequent or earlier screening if you have other risk factors, such as a family history of the disease.
Causes
In most cases, it's not clear what causes colon cancer. Doctors know that colon cancer happens when healthy cells in the colon become changed.
Healthy cells grow and divide in a way to keep your body functioning properly. But when a cell is damaged and becomes cancerous, cells continue to divide, even when new cells aren't...
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...rely is a routine component of treating rectal cancer, particularly if the cancer has passed through the wall of the rectum or traveled to nearby lymph nodes. Radiation therapy, normally combined with chemotherapy, may be used after surgery to shorten the risk that the cancer may recur in the rectum where it started.
Prevention
To prevent new cancers from taking off, scientists look at risk factors and protective agents. Anything that increases your chance of getting cancer is called a cancer risk factor; anything that lessens your chance of getting cancer is called a cancer protective factor. Some risk factors for cancer can be averted, but many cannot. For instance, both smoking and inheriting certain genes are risk factors for some types of cancer, but only smoking can be avoided. Normal excise and a healthy diet can help reduces the chances, but do not promise.
Surgery is the most common treatment for all stages of colon cancer. Cancer cells may be removed by one of the below procedures:
...tance. Things that may protect you from cancer are; a proper balanced diet and a strong immune system. Your body has a sort of, command center that controls the growth of skin. Sometimes the cell reproduction process goes wrong and the newly created cell is a mutation of the original cell. Most cell mutations do not survive long enough to become harmful but sometimes the genetics of the cell allows it to survive and the cell could become cancerous. Some things that make a cell cancerous are; it not being attached to the command center, when the cell doesn’t give notice to the signal sent to tell it to stop growing, and when the cell gains its own blood vessel network system. Cancerous cells can move around and take over other sections of the body which destroys the person. Cancer and heart disease and many other severe conditions are there for many years before you e
Colorectal cancer, or CRC, affects African American men and women more than Caucasians, at a rate 20% higher. This is concerning when faced with the mortality rates among African Americans, 28% higher for women and 14% higher for men than for Whites. African Americans are also more likely to be in later stages of the disease when diagnosed. There is a need to study and evaluate why these factors exist, as proper screening and early diagnosis can severely impact survival rates for CRC. One study attempts to find the solution through testing, however, this study slightly discredits itself along the way.
The acquisition of an immortalized proliferative potential is very important for human tumors because, otherwise, the tumors will not grow in number nor will they metastasize. Mutations in progenitor cells would not be transmitted too far as they have limited replication and proliferation ability. Thus, the growth of the tumors will be limited. Hence, if there is even a very small population of cells with the ability to proliferate continuously, there will be a source for productions of more cells for the tumor. Clonogenic assays have shown that, though most cells in a tumor have a limited ability to proliferate, a subset of cancer cells exist in these tumors that continuously proliferate and give rise to new tumors on transplantation.
Colorectal cancers are thought to develop slowly over a period of several years. Before a true cancer develops, there usually are precancerous changes in the lining of the colon or rectum. These changes might be dysplasia or adenomatous polyps. A polyp is a growth of tissue into the center of the colon or rectum. Some types of polyps (hyperplastic polyps and inflammatory polyps) are not precancerous. However, having adenomatous polyps, also known as adenomas, does increase a person’s risk of developing cancer, especially if there are many polyps or they are large.
..., while a cell undergoes cell cycle, when a cell comes in contact with another cell, it stops reproducing. However, cancer cells continue to duplicate repeatedly until there is a mass of cells or a tumor to form (see figure 9). Lastly, in cell division when there is a mutation or abnormality in the DNA, a normal cell stops dividing. However, a cancerous cell will continue to duplicate and form mutations (“Cell Biology and Cancer”). Also, cancer cells are harmful because they grow and duplicate with complete disregard to the functions and limitations of the body (see figure 10). Also, cancerous cells have the ability to spread through metastasis throughout parts of the body through the bloodstream. In terms of similar behavior to that of normal cells, cancerous cells also duplicate, but at a very different rate ("Cancer Cells vs. Normal Cells: What's Different?").
Colon cancer is the third most common cancer in men and women, responsible for more than 57,000 deaths in 2001 alone. Colon polyps, which can lead to colon cancer, are found in about 30-40% of people aged 60 or older- and the risks of polyps increase with age” (Lerche Davis, 2003). Most cases of colon cancer start as small adenomatous polyps. Many people experience no signs or symptoms in the early stages of colon cancer. Some signs and symptoms can include diarrhea, constipation, or any change in consistency of your stool that continues for longer than a month. Any bleeding from the rectum or blood found in the stool can also be a sign of colon cancer. Continuing abdominal pain, cramps, gas, weakness, fatigue and unexplained weight loss could all be signs of rectal cancer in the patient (Staff,
Cancer is the term used to describe a group of diseases consisting of hundreds of ailments and although there exists so many different types of cancer, they all begin in a similar way. The body is made up of over a trillion cells, and cancer is the uncontrolled growth of malfunctioning cells in the body (Dawson, 1996). “Normal body cells grow, divide, and die in an orderly fashion. During the early years of a person’s life, normal cells divide faster to allow the person to grow. After the person becomes an adult, most cells divide only to replace worn-out or dying cells or to repair injuries” (American Cancer Society, 2012).
Colon cancer is a deadly cancer but sometimes you can survive through it if you find out sooner that you are diagnosed with colon cancer. People that are older than 50 are usually diagnosed with colon cancer. Colon cancer can spread different part of your body and cause you a lot of pain. Doctors have found some treatments to fix colon cancer but when you are on stage three or four sometimes there is nothing that they can do. Doctors are working hard to find new treatments and maybe someday colon cancer would not be a cancer that can kill you anymore.
...rapy and surgery, its used only if the cancer comes back. Surgery is the treatment of injuries of the body by incision with instruments. Depending on what stage the cancer is in, the patient may need multiple surgeries to completely treat the cancer. For the later stages in the cancer, surgery is the most common treatment. The option to have surgery depends on the size and the location of the cancer. With all this being said, if the cancer is found early enough, there is a better chance of it getting cured. Some patients decide to use either chemotherapy or radiotherapy along with surgery, just to be safe. “For many patients, surgery will be combined with other cancer treatments, such as chemotherapy, radiation therapy or hormone therapy” (Cancer Treatment Centers Of America parag.3). By combining these treatments, there is a better chance of the cancer being cured.
Colon cancer develops in the part of the gastrointestinal tract that absorbs water and minerals before waste products are disposed via the rectum. In women endometrial cancer is related to colon cancer. This type of cancer is the second leading cause of death due to cancer in the United States. Over one-hundred fifty thousand individuals will be diagnosed this year and this cancer will probably be responsible for about 47,900 deaths in 1999 (http://www.cancer.org). Most colon cancers are adenocarcinomas that develop from the glandular cells. Ninety percent of all colon cancer cases will develop in individuals after 50 years of age. Ninety percent of all tumors arise from polyps that are commonly found in people older than 50. Prevention includes regular exercise and a diet high in fiber. The most important risk factor is age. Medical screening includes a yearly blood occult test after age 50 and a colonoscopy every 3 years after age 50. Regular screening detects polyps that have become precancerous. If regular screening is not done, the cancer is not detected until blood is found in the...
Cancer has been seen in humans as one the most potentially fatal disease for thousands of years and only in the recent couple of hundred years have we discovered that most information necessary to bring us to today’s understanding and knowledge (Kenny 2007, Weinberg 1996) was achieved by extensive research of cells, DNA, and epidemiology studies. As we know, currently cancer is acknowledged as having over a hundred different diseases, and is known to be the result of mutations of the genes and almost similar DNA which are responsible for the amount of cell division and production (Kenny 2007). Restraint of cell growth modulators can be a direct lead and result of certain tumours being developed and subsequently allow these tumours to acquire the ability to attack and occupy the bloodstream and essentially be able to travel via the bloodstream to other parts and organs in human bodies which is known as metastasis (Loeb et Al 2003). Once this has occurred , the cancer is then categorized as malicious and becomes a dangerous and serious threat to the carrier (Weinberg 1996). In this essay I will describe and explain the process of this and how our genes mutate and lead to metastasis of cancer cells.
Cancer has become the one of the most feared things for human beings. The various type of cancer have been discovered and there are still a lot of it that undiscoverable. Cancer is a complex disease that have a group of disease. The cancer itself cannot be describe by words. The causes of this cancer is still not being able to be discovered fully. There are only minor factor that can lead to this disease. The carcinogens are believed to be one of the causes that lead to cancer such as asbestos, radon gas, tobacco, PVC and much more from our chemical industries. The environment especially near to the industrial that produce chemical waste can be one of the causes lead to cancer. Cancer also have relation with our age, lifestyle, and diet and also can be genetically inherited. It is believed that older people have higher tendency to get cancer than younger people. Our lifestyle and diet also plays a role causing a cancer by our daily life routine. Smoking tobacco and eating unconsciously (still in research) can also increase the possibility to get cancer especially lung cancer that cause by smoking tobacco. There are several cases, cancer were inherited from their parents. Various type of viruses such as HIV, HPV, EBV and many more virus has a high capabilities to increase the chance a patient to get a cancer because these viruses lower their body immunity to disease.
The primary ways to detect these early-warning symptoms or signs include blood tests, X-rays, and other medical screenings. When there is family history of certain condition such as colon cancer, it is additionally important for people to get early screenings to maintain proper health.
Everyone is born with certain genetic mutations that make the them more likely to develop cancer in a later time in life. Though they might have a genetic feature, cancer will not develop unless triggered by environmental factors such as air and water pollution. As a matter of fact, my grandfather started smoking alongside consuming heavy amounts of alcohol around the age of 15, smoking and heavy alcohol intake have been considered as one of the potential causes of colon