Capgras Delusion

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Introduction The Capgras Delusion is one of the rarest and colorful syndromes in neurology. The patient fails to recognise the faces of close acquaintances and calls them as an ‘imposter’. They claim that the person ‘looks like’ or is ‘identical to’ someone they know, while continuing to believe that they are two different individuals. The delusional belief is strongest when the putative imposter is present [2]. Capgras delusion is classified as a delusional misidentification syndrome, a class of beliefs where the patients have delusional beliefs that involves misidentification of people, places or objects. The delusion is mostly common in patients diagnosed with neurodegenerative diseases; such as Alzheimer’s disease (2% - 30%) [8], schizophrenia (15%) [9] and dementia. It has also been seen in patients suffering from brain injury causing lesions, suggesting that the syndrome has an organic basis. History Capgras Syndrome (CS) is named after Joseph Capgras (1873-1950), a French psychiatrist. He first described the disorder on the case of a French woman, who complained that the corresponding ‘doubles’ had taken places of her husband and other people she knew. Capgras and Reboul-Lachaux first called the syndrome “l’illusion des sosies”, which is translated as “the illusion of look-alikes” [1]. The Capgras Syndrome was initially considered purely as a psychiatric disorder. Such delusions of doubles was seen as one of the various symptoms of schizophrenia, and purely a female disorder [2]. Most of the explanations initially proposed were psychoanalytical in nature. From 1980s neurologists started analyzing the co-existing organic brain lesions originally thought to be unrelated to the symptoms. ... ... middle of paper ... ...atic without autonomic responses to familiar faces: differential components of covert face recognition in a case of Capgras delusion. Cognitive Neuropsychiatry 5, 255–269. [18] Tranel, D., Damasio, A.R., 1985. Knowledge without awareness: an autonomic index of facial recognition by prosopagnosics. Science 228, 1453–1454. [19]Tranel, D., Damasio, H., Damasio, A.R., 1995. Double dissociation between overt and covert recognition. Journal of Cognitive Neuroscience 7, 425–432. [20] Reid, I., Young, A.W., Hellewell, D.J., 1993. Voice recognition impairment in a blind Capgras patient. Behavioural Neurology 6, 225–228. [21] Shah, N.J., Marshall, J.C., Zafiris, O., Schwab, A., Zilles, K., Markowitsch, H.J., Fink, G.R., 2001. The neural correlates of person familiarity: a functional magnetic resonance imaging study with clinical implications. Brain 124, 804–815.

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