Brain Corpus Callosum

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Purpose As the largest fiber tract in brain, corpus callosum (CC) constitutes the major connection between two hemispheres of brain. Several lines of evidence indicated that midsagittal plane of CC is affected in patients suffering from Multiple sclerosis (MS). To find probable morphologic changes in CC segments in MS, magnetic resonance imaging (MRI) was used.
Materials and Methods: In this line, we analyzed brain MRI images of 54 MS patients compared to 128 healthy individuals MRI images by PmsDViewer software. Data were analyzed by Student’s t-test statistically.
Results: MRI morphometric analysis indicated that the proportion of total area of rostrum and genu to the total area of CC (ARG/ACC ratio) significantly increased in MS patients

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