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Essay on history blood transfusion
Essay on history blood transfusion
Essay on history blood transfusion
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There have been many advancements in medicine over the centuries. Some have been very controversial, one example is the idea of human to human blood transfusions. Blood transfusions have not always been as successful as they are today. The procedure was even made illegal in some countries. The pioneer of successful human to human blood transfusions was James Blundell, born in London, 1791 (Dzik, 2007). This essay will describe the discovery of blood transfusion, also how the discovery of blood transfusion came about, the effect or importance of successful blood transfusion, and the future of blood transfusions.
Blood transfusion is a safe, common procedure in which blood is given to people through an intravenous (IV) line in one of the blood
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And more than forty-two thousand patients are treated with blood or blood products in New Zealand each year (NZ Blood, 2016). As medical technology advanced, phlebotomists would separate plasma from the blood, and use this to infuse patients who had liver disease, red blood cells would be used to transfuse into cancer patients, or white blood cells into patients with anemia, or to help with chemotherapy (replacing bad blood cells with good blood cells. The largest group of people who benefit from blood transfusion are mainly cancer patients, making up the largest number of 29% of blood products used specifically, either when they have surgery. The fact that blood is able to be separated into several parts is the main reason so many people benefit from receiving blood transfusions. Unfortunately, although people use forty-two thousand different blood components on average per year, only one hundred and twenty-five thousand units of blood per year are collected in New Zealand (NZ Blood, 2016). Today scientists use stem cells to generate new blood in the patient’s body, moreover some research shows that in the next ten to fifteen years’ scientists are hoping to grow blood in agar plates. As technology advances and the number of people needing transfusion increases, scientists are experimenting with new ideas, just as James Blundell first did in 1818, and although the idea might seem outrageous now, in ten to thirty years from now it could be as common, as per what people know
BioPure Corporation, which was founded in 1984 by entrepreneurs Carl Rausch and David Judelson, is a privately owned biopharmaceutical firm specializing in the ultra purification of proteins for human and veterinary use. In 1998 Biopure pioneered the development of oxygen therapeutics using “Hemoglobin”, a new class of pharmaceuticals that are intravenously administered to deliver oxygen to the body's tissues. Biopure's two products, Hemopure for human use, and Oxyglobin for animal veterinary use, both represented a new Oxygen based treatment approach for managing patients' oxygen requirements in a broad range of potential medical applications. The factor distinguishing Biopure’s two products from other blood substitute products being developed by two possible rivals, Baxter International and Northfeild Laboratories, is that its hemoglobin based source is bovine rather than human and was derived from the blood cells of cattle. Both of Biopure’s blood substitute products were in the final stages of the approval process of the Food and Drug Administration (FDA) in 1998. Oxyglobin had just received the FDA’s approval for commercial release declaring it safe and effective for medical use. Hemopure was entering final Phase 3 clinical trials and was optimistically expected to see final FDA approval for release in 1999. The FDA approval of Oxyglobin and its possible subsequent release into the veterinary market caused concern over whether the early release of Hemoglobin would impinge BioPure’s ability to price Hemopure when the product finally received approval. Given that the two products were almost identical in properties and function, it was thought that the early release of Oxyglobin would create an unrealistic price expectation for Hemopure if released first.
Thesis: I will explain the history of organ transplants, starting with ancient ideas before modern science until the 21st century.
Many of the subject’s were twins, mostly identical. Twins when through the worst of the surgeries, including blood transfusions. Doctors drained one twin of his blood and inject it into the other twin to see what would happen. Blood would be drawn from each twin in large quantities about ten cubic centimeters were drawn daily. The twins who were very young suffered the worst of the blood drawing. They would be forced to have blood drawn from their necks a very painful method. Other methods included from their fingers for smaller amounts, and arms sometimes from both simultaneously. The doctors would sometimes see how much they could withdraw until the patient passed out or died.
It was during this time that doctors and nurses, through experience also demonstrated that blood could be stored and then safely transferred from patient to patient saving countless soldiers’ lives.
(Topic sentence) According to the Health Care, Medicine, and Science, by Deborah Porterfield (1st citation), the word phlebotomy means “obtaining blood from a vein.” (P.34) Phlebotomy came a long way, as it was one of the traditional ways of medicine. According to Jamie Cohen (2nd citation), this practice is thought to have originated from ancient Egypt. From Egypt, this practice was starting to get used in Europe. Erasistratus, a popular physician in ancient Greece, believed that illness was caused due to too much blood. A little later, the Roman Empire believed in Erasistratus’s theory and performed phlebotomy more (P.1). With these two empires rising to the top, phlebotomy was spread throughout the world, including to places like India and Arabia as well. Years later in Europe, churches were not a big fan of cutting people open and let them bleed. So, who performed this...
Blood doping could have opposite effect of those intended. A large infusion of red blood cells could increase blood thickness and cause a decrease in cardiac output and a reduction in oxygen content. Both would reduce aerobic capacity. The human heart was not designed to pump thickened blood throughout the body and, therefore, it could lead to a multitude of problems. The diseases that can be contracted from autologous blood transfusion are severe. Even more frightening is the list of diseases that can be contracted through homologous blood transfusion. It includes hepatitis, AIDS, malaria, and CMV. In addition, shock is a factor to be aware of.
Although blood transfusions had been used before the First World War, many were not successful due to lack of knowledge in this type of treatments. World War I pushed the development of blood transfusions, allowing them to be safer. Before the war in the 17th century, blood transfusions often occurred with the use of animal blood, a practice that did not achieve desired results. These transfusions often times came from sheep, and although they were sometimes successful, it was discovered that any large amounts of transfusions would cause death. Coming to the conclusion that animal blood transfusions did not save lives, scientists looked to humans for human to human transfusions. Many of these attempted transfusions were met with failure but in 1818, Dr. James Blundell accomplished the first successful human blood transfusion; four ounces of blood were transferred to the patient from her husband. From that moment on, doctors began to learn even more about blood transfusions and how to do them properly. By 1901, the four human blood groups were discovered by Karl Landsteiner; with less differences in the bloods transfused together, coagulation and clumping amounts decreased. This benefited many lives in that toxic reactions to the wrong types of blood did not occu...
Imagine finding your child pulse less and not breathing. What a terrifying thought! Would you know how to save your child’s life? The number of parents that do not know CPR is astounding. Simply knowing CPR could make a dramatic difference in the lives of you and your loved ones.
VI. Some individuals requiring blood are surgical patients; burn victims; accident victims; anemics'; hemophiliacs; seriously ill babies; and persons suffering from leukemia, cancer, kidney disease and liver disease.
Jehovah's witnesses believe that the bible has prohibited ingesting blood and have concluded and applied the same ruling on accepting blood transfusions, donating blood or storing it for transfusion. It is considered as a non-negotiable religious stand and it is believed that those who accept and appreciate life as a gift from god should not sustain it by doing something that would condemn it, such as accepting blood. Often, the doctor's ability to help a patient is limited by their beliefs, which are to be respected. Healthcare professionals can only advise their patients of the benefits of receiving the appropriate treatment whilst explaining the risks and complications that are associated with refusing it; as the decision to proceed with or against medical advice is ultimately the patient’s choice. Providing the patient with an atmosphere of acceptance away from conservative parties that could influence their judgement negatively may allow them to make free decisions, allowing them to seek their best interest. However, shall they deny treatment and accept the consequences, it is the doctor’s duty to sympathise with and comfort them alongside doing their best to assist them and try to find ways around the presented obstacle, such as finding alternatives that would have the same desired effect as a blood transfusion. For example, alternatives such as cell-saver techniques, where the patient’s own blood is reutilized during a procedure may be considered [1]. For some patients, fractions of plasma such as albumin, cryoprecipitate may be accepted by the patient [1].
According to an ABC news article by Lupkin, one of the two U.S. health-worker, Dr.Brantly (who showed signs of improvement after receiving Zmapp) mentioned that he received a blood transfusion from a 14-year old Ebola survivor before his conditioned worsened. In conclusion, there is a strong theory that a Plasma (see figure 3) from an Ebola survivor could help an Ebola patient if particularly given early.
Blood donation is a very essential procedure in the health system. The process entails collecting blood from willing donors, testing it and then separating it into its components so that it can be used on patients. Whereas hospitals are the main users of the donated blood, they are not exactly authorised to collect, test and separate it in their own premises. Most of the health institutions get the blood from larger bodies such as the Red Cross or other Community based blood groups. Though initially faced with lots of problems, blood transfusion has been used since 1667 as a solution to some of human illnesses. Since then to now, hospitals have grown so dependent on blood donation and transfusion to save human life. With it being used and applied
The first successful case of stem cell therapy in human was reported in 1959. Bone marrow restorations were observed in leukemia patients who received total body irradiation subsequent by intravenous injection of their twins’ bone marrow (Thomas et al, 1957). Nevertheless, that effect was transient and the following bone marrow transplantation attempts in non-twin patients and donors can eventually lead to patient’s death from graft-versus-host disease (Mathé et al, 1965). During that time, the safety of hematopoietic cells transplantation was not guaranteed because of the limited knowledge in human histocompatibility and immunosuppression. However, the turning point came after the discovery of human leucocyte antigen (HLA) groups (Dausset, 1958; van Rood et al, 1958), HLA typing and compatibility testing were performed prior to the transplantation. In addition, the improvement of immunosuppressive protocol also helps bringing the bone marrow transplantation to become more and more successful (Donnall and Hutchinson, 1999).
Like a super hero, we rushed into delivery room like a flash. We put our lab coats on, then flew to where our patient was. We extracted blood from a mother who was fighting between life-and-death for her and for her baby's life. I saw her pain, her cries, her sweat and blood.
The advances in modern medical science in the near future are dependent upon the advances of methods and procedures that by today’s standards are considered to be taboo and dangerous. These methods will not only revolutionize the field of medicine but they will be the forerunners to a whole knew way to treat people. For these advances to take place several key steps need to be taken both medically and politically. In this paper I will attempt to explain what methods and procedures will be the future of modern medicine, how these methods and procedures can benefit mankind, and finally what changes will be needed in the fields of medicine and politics.