Barbiturate. Now where would you think of a name like that? Legend has it that this drug was derived when a 29 year old research assistant, Adolph von Baeyer, was working in his Belgian laboratory in 1863 when he took the condensation of malonic acid and combined it with Urea. Von Baeyer went downtown to a local pub to celebrate where some army officers where celebrating Feast Day of Saint Barbara. So he took the name Barbara and combined it with the chemical that mostly made up this new acid and came out with barbituric acid.
In 1912, two German scientists used von Baeyer’s acid to synthesize a new drug, barbitol. What they were looking for was a drug that would combat the effects of anxiety and nervousness. They were successful but the side effects were too great.
Barbiturates are drugs that cause depression of the central nervous system and are generally used to induce europhia. D.C. Heath’s Perspectives on HEALTH defines europhia as a feeling of intense happiness and well being. Most users take the pills orally, often with alcohol. The most common way to get the barbiturates is in tablet form. Other ways to get barbiturates include ampoules, syrup, or capsules. For injection, which is rarely used because of its risk factor, capsules are opened and the powder is added to water. However, this can cause damage to the veins. Barbiturates come in different types such as Soneryl, Nembutal, Amytal, and Tuinal. Small doses relax the user, depressing the nervous system while the effects last up to 8 hours depending on the dosage. Large doses can cause loss of co-ordination, slurred speech, and give the appearance of being drunk. The lethal dose is especially close to the normal dose that is why it is very risky to use barbiturates. On the street, barbiturates are classified by their color such as “blues” which are amytal, and “yellow jackets” which are nembutal, or “red birds” or “red devils” which are seconal red.
Barbiturates can be classified as short acting (4 hours or less), intermediate acting (4-6 hours), and long acting (6 hours or more.) Also, there is a special Ultra-Short category, which happens before the full injection of the barbiturate is complete.
Dependence upon this drug is almost guaranteed. Each time the dosage must be raised to get the same “high” feeling. People who use these drugs daily for prolonged periods of time may become psychologically and physically dependent.
Antiarrhythmic agents are used to suppress abnormal rhythms of the heart. Many attempts have been made to classify antiarrhythmic agents. There is a problem from the fact that many of the antiarrhythmic agents have multiple actions, making any classification accurate. Betapace (sotalol) comes in tablets and solution for oral a...
Benzyl bromide, an unknown nucleophile and sodium hydroxide was synthesized to form a benzyl ether product. This product was purified and analyzed to find the unknown in the compound.
I agree with both sources because after reading Baseball Saved Us I was blown away with the writing style and the illustration. It is a heart-felt story and leaves readers touched after the insight of what was a serious historical event. The book drove me to do extra research to get an understanding of what life was possibly like for those
“The Lottery” is a short story about an event that takes place every year in a small village of New England. When the author speaks of “the lottery” he is referencing the lottery of death; this is when the stoning of a village member must give up his or her life. The villagers gather at a designated area and perform a customary ritual which has been practiced for many years. The Lottery is a short story about a tradition that the villagers are fully loyal to and represents a behavior or idea that has been passed down from generation to generation, accepting and following a rule no matter how cruel or illogical it is. Friends and family become insignificant the moment it is time to stone the unlucky victim.
Physostigmine is a drug used for the treatment of severe anticholinergic syndrome. Such as nervous delirium, urinary reten...
Tradition is huge in small towns and families and allows for unity through shared values, stories, and goals from one generation to the next. Shirley Jackson’s “The Lottery” carries that theme of tradition. The story follows a small town that performs the tradition of holding an annual lottery in which the winner gets stoned to death. It (tradition) is valued amongst human societies around the world, but the refusal of the villagers in “The Lottery” to let go of a terrifying long-lasting tradition suggests the negative consequences of blindly following these traditions such as violence and hypocrisy.
A reason the box symbolizes the town is because of the way the box is handled . Literary critics and author of American writers Jay Parini concur “The box is only handled by the men of the village.” (Parini 122). Mr. Summers, the conductor of the lottery, is in charge of the box. Just like the box, the town is male dominated. Throughout the entire story the men are in charge. It is the men who help out Mr. Summers by holding the box steady while he stirs the papers inside the box and he specifically calls for “some of you fellows” (Jackson 1) addressing the men standing by him. Also the men are the ones who draw up the lists of families while the women wait patiently a distance away. Furthermore, it is the“heads of household” who draw for their families. If the man of the family is unable to draw, then a son can draw in his place. A woman is allowed to draw for the family only on the occasion that no other man is able to draw (Perini 123). A...
Surprisingly, some people actually take this drug on purpose for the euphoric high that it produces. This practice is also extremely dangerous because in addition to the side effects, the drug can be addictive. This means that the longer you use it, you need to use more and more to reach the same level of “high” and if you stop taking it, you go through withdrawal.
Anticholinergic Deliriants or Belladonnoids, show the most promise as chemical compounds used to incapacitate. Belladonnoids cause delirium in casualties and blocks both the central and peripheral muscarinic effects of acetylcholine. BZ is the most common of the synthetic Belladonnaoids. BZ can create mild delirium, loss of attention and drowsiness at low doses. To full blown ambling around looking lost and shouting in higher doses. I describe this as Zombie like trance. Recovery can take 24hrs from onset of symptoms. However the onset of symptoms is relatively slow, making BZ ineffective for military use.
Viagra is taken orally. It is quickly absorbed into the system and usually reaches its peak concentration in about 30 to 120 minutes. However, as with most orally administered drugs, taking the pill on a full stomach will slow down its absorption (Sildenafil Citrate, par. 5). Viagra is metabolized in the liver by the cytochrome p450 system. It is converted into a metabolite that has properties similar to that of the pre-metabolized drug. Viagra and its metabolite have a "terminal half-life of about 4 hours" (Sildenafil Citrate, par. 4). Finally, Viagra is excreted primarily through feces in the form of metabolites (Sildenafil Citrate, par. 7).
Americans day after day live much of their lives following time-honored traditions that are passed down from one generation to another. From simple everyday cooking and raising children, to holidays and other family rituals, tradition plays a significant role on how they go by there everyday lives. In Shirley Jackson's short story, "The Lottery," the citizens of a small farming town follow one such tradition. A point is made regarding human nature in relation to tradition. The story begins on a beautiful summer afternoon. The town's citizens are eager, gathering in the town square in order to take part in the yearly lottery. With the story focused around one particular family, the Hutchinsons, who are so anxious to get it all over with until they find that one of their members is to participate in the lottery's closing festivities, Tessie. Of course unlike your typical lotteries, this is not one that you would want to win. The one chosen from the lottery is to undertake a cruel and unusual death by stoning at the hands of their fellow townsmen for the sake that it may bring a fruitful crop for the coming harvest season. Ironically, many of the towns people have suggested that the lottery be put to an end, but most find the idea unheard of being that they have lived in it's practice for most of their lives. The story conveys a message that traditions may be valued so highly that those in their practice may do everything they can to ensure that they continue in accordance. From this a question arises. How far would one go to ensure their sacred traditions remain unscathed?
“The Lottery” written by Shirley Jackson is about a town coming together to hold a lottery. The twist being the winner of the lottery gets stoned to death by the town members. No one really know why their town and the ones surrounding it keep the practice going. But no one stops the ceremony they just know it is an event that happens every year for the past seventy seven years. Through the characters and the ritual of the lottery Jackson demonstrates how people blindly follow their traditions without knowing their history.
E. Fuller Torrey, author of "The Treatment of Schizophrenia: Medications", believes that even though antipsychotic drugs cannot cure psychosis they do control it. Antipsychotic drugs were introduced in 1952 by a French psychiatrist by the name of Pierre Deniker. These drugs were split into two classes, first generation and second generation. First generations were considered "typical" because of their ability to block dopamine receptors while second generations were referred to as "atypical" for their action on other neurotransmitters. In the beginning, antipsychotics had some serious side effects, which included acute dystonia reactions, EPS, Akathisia and Parkinsonian - like symptoms. New and improved antipsychotic drugs have been created to have the same effectiveness but with fewer side effects. Overall "70 percent improved, 25 percent improved minimally or not at all and 5 percent got worse." The main purpose of these drugs are to "reduce symptoms, shorten hospitalization, and reduce re-hospitalization."
Shirley Jackson’s “The Lottery” tells a story of a tradition passed on from one generation to the next that has allowed ritual murder to become a part of the town’s history. “The Lottery” shows that these traditions have the ability to destroy a society. “The Lottery” exhibits the dangers of blindly following unexamined traditions. The perils of blindly following unexamined rituals are demonstrated when the people gather in the square while the children gather stones, when Bill Hutchinson willingly gives up his wife without a second thought, and when Tessie Hutchinson is stoned.
Schmied, L. A., Steinberg, H., & Sykes, E. A. B. (2006). Psychopharmacology's debt to experimental psychology. History of Psychology, 9, 144-157.