Anatomy and Physiology of Diabetic Retinopathy
Retinopathy is usually found in people that have high blood pressure and diabetics. It is most commonly in people that have diabetes. The cause of retinopathy occurs when the blood vessels swell and leak fluid or even close off completely. Some cases abnormal new blood cells grows on the surface of the retina. People with diabetic retinopathy get it in both eyes. Most diabetics do not notice any visual complications at an early stage’s of the disease. As this disease progresses, usually cause vision loss that usually cannot be reversed. Different parts of the retina can be affected like the macula, the outer part of the retina or both. Which can make retinopathy more serious. Background retinopathy doesn’t change the sight. With this you have tiny leaks fluid and tiny bleeds in various parts of the retina. Pre-proliferative retina is more extensive, signs of blood flow becoming more restive, but not yet showing signs of new blood vessels growing. Maculopathy shows damage to the macula. Proliferative retinopathy when damage blood vessels in the retina make chemicals called growth factors. The form new blood vessels which are not normal. Without laser treatment, vision is most likely become badly affected.
The cornea is the dome shape outer covering of the eye and also where light is focused. There are no blood vessels in the cornea due to the blood vessels would block the light from entering. It receive it nutrients and oxygen from tears and aqueous humor. The sclera is the outer white portion of the eye. Which supply protection and structure of the inner parts of the eye. Conjunctiva is a mucus layer that keep the eyes moist. This also covers the sclera and the ...
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...s leads to insufficient transportation of glucose into the cells for energy production and conversion of excess glucose into glycogen or fat storage. So glucose accumulates in the blood plasma causing hyperglycemia.
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Works Cited
: Guy J Petruzzelli, M. P., & Chief Editor: Arlen D Meyers, M. M. (2013, 29 October). Retrieved from Medscape MedPulse: http://emedicine.medscape.com/article/835021-overview
M.D., T. R. (N/A, N/A N/A). Anatomy of the Eye. Retrieved from Root Eye Network Inc.,: http://www.ophthobook.com/chapters/anatomy
N/A. (2007-20014, N/A N/A). Cavities and chambers of the eyeball. Retrieved from Medicalook: http://www.medicalook.com/human_anatomy/organs/Cavities_and_chambers_of_the_eyeball.html
N/A. (2013, N/A N/A). Structures of the Eye. Retrieved from Innvista.com : http://www.innvista.com/health/anatomy/structures-of-the-eye/
ED. Mayo Clinic Staff -. Mayo Foundation for Medical Education and Research, 05 Jan 2012. Web. The Web.
The pathophysiology of diabetes mellitus in is related to the insulin hormone. Insulin is secreted by cells in the pancreas and is responsible for regulating the level of glucose in the bloodstream. It also aids the body in breaking down the glucose to be used as energy. When someone suffers from diabetes, however, the body does not break down the glucose in the blood as a result of abnormal insulin metabolism. When there are elevated levels of glucose in the blood, it is known as hyperglycemia. If the levels continue to remain high over an extended period of time, damage can be done to the kidneys, cardiovascular systems; you can get eye disorders, or even cause nerve damage. When the glucose levels are low in one’s body, it is called hypoglycemia. A person begins to feel very jittery, and possibly dizzy. If that occurs over a period of time, the person can possibly faint. Diabetes mellitus occurs in three different forms - type 1, type 2, and gestational.
Glaucoma, one of the leading causes of blindness, is estimated to affect 1 of every 50 adults. Although glaucoma can occur at any age, the risk of developing the disease increases dramatically after the age of 35. Glaucoma is also more likely to develop in patients who are severely nearsighted, have a family history of the condition, diabetics and Black or African American. This disease often goes unnoticed until permanent vision loss has occurred. Visual damage from glaucoma can be prevented by early diagnosis and careful treatment. Glaucoma is related to elevated fluid pressure of the eye which is causing loss of side vision. It is a series of diseases which damage the optic nerve. Damage to the optic nerve and retina causes blind spots in the field of vision. When the entire nerve is destroyed, blindness will occur. Glaucoma is usually caused by an increase in the fluid pressure in the eye. The front part of the eye contains a clear, nourishing fluid called aqueous which constantly circulates through the eye. Normally, this fluid leaves the eye through a drainage system and returns to the blood stream. Glaucoma occurs from an overproduction of fluid or when the drainage system becomes blocked, causing fluid pressure to increase. The high pressure causes damage to the optic nerve, resulting in permanent vision loss. The exact reason the fluid system in the eye stops functioning properly is not completely understood
Glaucoma is a disease of the eye and it is fluid pressure within the eye rises and if the eye is left untreated the patient might lose vision or maybe even blind. But this disease is generally affects both eyes but although one of their eyes may have more severe signs or symptoms then the other eye. When you have glaucoma there are small spaces in the front of the eye and they are called anterior chamber. There is clear liquid that flows in and out of the anterior chamber and the fluid nourishes and bathes nearby the tissues. And if the patient has glaucoma the fluid dose not drain like it should drain but the fluid drains out of the eye. And this may lead to fluid build up and pressure inside the rises of the eye. Unless the pressure is brought down and controlled and the optic nerves and some of the other parts of the eye might become damaged leading to ...
Retinitis pigmentosa is a genetic disorder that causes blindness in the people that are affected by it. I chose retinitis pigmentosa because my grandmother has this genetic disorder. The disorder is very costly on those who have it. The disorder has robbed my grandmother of the life she wanted. She is no longer able to do the things she once was. She is legally blind, cannot drive, and has trouble getting around crowded areas. Retinitis pigmentosa was discovered by Doctor Donders in 1857. Retinitis pigmentosa is a very serious disorder in how it occurs, its signs and symptoms, its prevalence, and how its treated.
The Cleveland Clinic, 26 Dec. 2007. Web. 1 Mar. 2010. . "
Sight helps us navigate the world around us more than any of our other senses. In a fraction of a second, our eyes work with our brains to tell us the size, shape, and texture of an object. They also tell us how close it is and if it’s still or moving. The structures of our eyes are incredibly complex, despite how small they are compared to the rest of our organs. The human eyes are extremely delicate. The visible part of the eye is protected by the eyelids and eyelashes, which keep out dirt, dust, and harmful bright light.
Diabetes refers to a set of several different diseases. It is a serious health problem throughout the world and fourth leading cause of death by disease in the country. All types of diabetes result in too much sugar, or glucos in the blood. To understand why this happens it would helpful if we understand how the body usually works. When we eat, our body breaks down the food into simpler forms such as glucose. The glucose goes into the bloodstream, where it then travels to all the cells in your body. The cells use the glucose for energy. Insulin, a hormone made by the pancreas, helps move the glucose from bloodstream to the cells. The pathophysiology of diabetes mellitus further explains the concept on how this disease works. Pancreas plays an important role of the metabolism of glucose by means of secreting the hormones insulin and glucagon. These hormones where then secreted by Islets of Langerhans directly to the blood. Inadequate secretion of insulin results on impaired metabolism of glucose, carbohydrates, proteins and fats which then result to hyperglycemia and glycosuria. Hyperglycemia is the most frequently observed sign of diabetes and is considered the etiologic source of diabetic complications both in the body and in the eye. On the other hand, glucagon is the hormone that opposes the act of insulin. It is secreted when blood glucose levels fall.
...in sources of energy. When cells cannot absorb sugar, you can become fatigued or feel exhausted” (Healhline), complain of blurred vision” In the short term, high glucose levels can cause a swelling of the lens in the eye. This leads to blurry vision. Getting your blood sugar under control can help correct vision problems. If blood sugar levels remain high for a long time, other eye problems can occur” (HealthLine), experience nocturia “Elevated glucose levels force fluids from your cells. This increases the amount of fluid delivered to the kidneys. This makes you need to urinate more. It may also eventually make you dehydrated” (Healthline), and have sores and cuts that will not heal “Elevated glucose levels may make it harder for your body to heal. Therefore, injuries like cuts and sores stay open longer. This makes them more susceptible to infection” (HealthLine).
Turner, B. J., Newschaffer, C. J., Zhang, D., Fanning, T., & Hauck, W. W. (1999). Translating clinical trial results into practice. Annals of Internal Medicine, 130(12), 979-986.
Many signs include a "white pupil," also known as leukocoria. Retinoblastoma can occur in either one or two eyes (Paul T. Finger, Pg. 1). This abnormal white pupillary reflex is sometimes referred to as a cat's eye reflex. Another sign of retinoblastoma is a crossed eye (Ambramson, Ch3). Leukocoria doesn't always end up as being retinoblastoma, it can even result in: congenital cataract, Toxocara canis, Coat's disease, and persistent hypertrophic primary vitreous (PHPV) (Finger, Pg.2). Retinoblastoma occurs when there's a mutation or deletion of the q14 band of chromosome 13 (Finger, Pg. 1). Symptoms can be painful if not treated quickly. Some include a red, painful eye, swelling of the surrounding eye, poor vision, dilated pupil, even extra fingers or toes, and retardation (Ambramson, Ch3).
U.S. National Library of Medicine, 26 Sept. 2011. Web. The Web. The Web. 19 Nov. 2013.
JAMA: Journal of the American Medical Association. 14 Nov. 2001: 2322. Academic Search Complete. Web.
the cornea and the sclera. The cornea is what covers the iris, and is the
As further protection, the eyelids automatically close when an object suddenly moves close to the eye.Parts Of the EyeThe eye is made of 3 coats, or tunics. The outermost coat consists of the cornea and the sclera. The middle coat contains the main blood supply to the eye and consists of the choroid, the ciliary body, and the Iris. The innermost layer is the retina.Cornea and ScleraThe Sclera, or the white of the eye, is composed of tough fibrous tissue. On the exposed area of the eye the scleral surface is covered with a mucous membrane called the conjunctiva.