Advantages And Disadvantages Of Aerosols

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The Components of Aerosols: [1] 1. Propellant 2. Container 3. Valve 4. Actuator 5. Product concentrate 1. The Propellant: It helps in developing the pressure that is required within the container. It also provides the driving force that is needed to expel the medicinal agent out of the container. It is of two types: i) Liquefied Gas Propellants ii) Compressed Gas Propellants i) The Liquefied Gas Propellants: These contain gases that are reduced to pressure that makes them liquid but in the headspace it is a gas. The pressure remains constant throughout the container that prolongs the life of the container. Eg: Cholrofluro carbons Hyrdrocarbons ii) The Compressed Gas Propellant: The headspace contains liquid. When the aerosol …show more content…

Solvents are usually blended in to mix well with the active ingredients to get the better effect of the drug.(6) ADVANTAGES OF AEROSOLS MEDICAMENT: . The constituents can be easily removed from package and without contamination and exposure. . They are easily administered without aid of others and are easy to apply. . As Aerosols is directly applied to the affected area thus onset of action is faster than other dosage form. . The distribution of aerosols is very good. . Due to the closed packing of aerosols there is no direct association with the aerosols. . Aerosols can avert the first fast metabolism and can also avert inactivation of drugs by enzymatic and PH action of the intestine. . No microorganisms can enter in aerosol products. . Aerosols container can preserve photosynthetic medicaments except those of gas container. . A refined mist drug is manufactured for inhalation purpose. . It provides a cooling effect. . Irritation can be reduced by applying aerosol medicaments without even touching the skin of effected area. (7) DISAVANTAGES OF AEROSOLS MEDICAMENT: . The clearance of empty aerosols container is

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