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the importance of dna profiling criminal investigation
fingerprint in criminal investigation
about dna fingerprinting
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DNA Fingerprinting
It is widely known that each individual has a DNA profile as unique as a fingerprint. Actually, over 99% of all 3 billion nucleotides in human DNA which we inherit from each parent are identical among all individuals. However, for every 1000 nucleotides that we inherit there is 1 site of variation or polymorphism, in the population. These DNA polymorphisms change the length of the DNA fragments produced by the digestion of restriction enzymes . The resulting fragments are called restriction fragments length polymorphisms. Gel electrophoresis can be used to separate and determine the size of the RFLPs. The exact number and size of fragments produced by a specific restriction enzyme digestion varies from individual to individual.
DNA fingerprinting has proved valuable, not only for convicting felons and exonerating the innocent, but also for establishing maternity or paternity and proving family relationships. More exotic uses include the identification of missing children in Argentina, soldiers killed in war, and even the body of Nazi physician Joseph Mengele, the so-called "Angel of Death."
The way it started:
The fundamental techniques involved in genetic fingerprinting were discovered serendipitously in 1984 by geneticist Alec J. Jeffreys of the University of Leicester in Great Britain while he was studying the gene for myoglobin, a protein that stores oxygen in muscle cells. He found that the myoglobin gene contains many segments that vary in size and composition from individual to individual and that have no apparent function. Jeffrey called these segments minisatellites because they were small and they surround the part of the gene that actually serves as a genetic bluprint.
In certain situations, it is necessary to identify DNA retreived from a sample. When there is a
Deoxyribonucleic acid (DNA) is an acclaimed extraordinary discovery that has contributed great benefits in several fields throughout the world. DNA evidence is accounted for in the majority of cases presented in the criminal justice system. It is known as our very own unique genetic fingerprint; “a chromosome molecule which carries genetic coding unique to each person with the only exception of identical twins (that is why it is also called 'DNA fingerprinting ')” (Duhaime, n.d.). DNA is found in the nuclei of cells of nearly all living things.
Nowadays, DNA is a crucial component of a crime scene investigation, used to both to identify perpetrators from crime scenes and to determine a suspect’s guilt or innocence (Butler, 2005). The method of constructing a distinctive “fingerprint” from an individual’s DNA was first described by Alec Jeffreys in 1985. He discovered regions of repetitions of nucleotides inherent in DNA strands that differed from person to person (now known as variable number of tandem repeats, or VNTRs), and developed a technique to adjust the length variation into a definitive identity marker (Butler, 2005). Since then, DNA fingerprinting has been refined to be an indispensible source of evidence, expanded into multiple methods befitting different types of DNA samples. One of the more controversial practices of DNA forensics is familial DNA searching, which takes partial, rather than exact, matches between crime scene DNA and DNA stored in a public database as possible leads for further examination and information about the suspect. Using familial DNA searching for investigative purposes is a reliable and advantageous method to convict criminals.
DNA is a vital tool in forensic medicine, when it comes to tracking down that killer or finding that liar in the courtroom. However, DNA fingerprinting for example is also used to identify what a person did based off of their remains. “The U.S. military takes blood and saliva samples from every recruit so it can identify victims of mass disasters such as airplane crashes.” (Marieb, 2009, p.459). After the 9/11 attacks,
Easteal, McCleod, and Reed. DNA Profiling: Principles, Pitfalls and Potential. Switzerland: Harwood Academic Publishers, 1991.
It was in 1984 when Alec Jeffreys, a British geneticist, discovered that specific sequences of DNA did not add to the function of a gene but were still constant throughout it. (Britannica). Jeffreys called these minisatellites and determined that each individual organism had a unique arrangement of minisatellites (Britannica). In the early uses of DNA fingerprinting, it was only used for identifying genetic diseases and disorders but people quickly realized that it could be used in many different areas of science (hubpages). Years after the discovery of DNA fingerprinting, it had been used to solve the first immigration case, the first paternity case, and even helped identify the first identical twins (le.ac.uk). The first methods of DNA fingerprinting were accurate, but you would have had needed to acquire a large amount of DNA. Over time, the advancement of science has led to major advances that formed the basis of DNA profiling techniques. These newer methods are still used today and allow scientist to use skin, blood, semen, and hair to gather DNA (le.ac.uk). In 1988 DNA fingerprinting was used for the first time in a criminal investigation. Timothy Spe...
Deoxyribonucleic acid (DNA) has been used to analyze and prove innocence or guilt of suspects of crimes with great accuracy. DNA is part of everyday life. It is the heredity material in humans and almost all other organisms. While being part of an investigation. DNA has helped to solve crimes. There is a couple ways that DNA left behind can be tested to solve a crime. Either if the suspect has been caught and or had his or her DNA tested, or if he or she has left behind any biological evidence. Which then needs to be tested to see if it matches the DNA found in the crime scene to his or hers DNA. The result to this comparison may help establish if the suspect committed the crime.
DNA testing is one of forensic sciences core techniques. Everyone has there own individual DNA profile, even identical twins. DNA is in every cell of our body. In the 1980s, a British scientist named Sir Alec Jeffery's, developed DNA profiling. Our DNA can be separated from human cells found at a Crime Scene, with perspiration, blood, skin, the roots of hair, semen, mucus, and saliva. The Colin Pitchfork case was the first murder conviction established on DNA profiling evidence.
Once a crime has been committed the most important item to recover is any type of evidence left at the scene. If the suspect left any Deoxyribonucleic acid (DNA) at the crime scene, he could then be linked to the crime and eventually charged. A suspect’s DNA can be recovered if the suspect leaves a sample of his or her DNA at the crime scene. However, this method was not always used to track down a suspect. Not too long ago, detectives used to use bite marks, blood stain detection, blood grouping as the primary tool to identify a suspect. DNA can be left or collected from the hair, saliva, blood, mucus, semen, urine, fecal matter, and even the bones. DNA analysis has been the most recent technique employed by the forensic science community to identify a suspect or victim since the use of fingerprinting. Moreover, since the introduction of this new technique it has been a la...
"Using DNA to Solve Crimes." U.S. Department of Justice: National Institute of Justice. (September 9, 2014). Web. 29 May 2015.
DNA plays the important role as a biological identification. According to Norah Rudin, through a series of experiments in the 1900s, it is found that DNA, similar to a fingerprint, are unique. No two DNA are alike, which makes it perfect for identification, hence the term “DNA fingerprinting” (7). Through a small amount of DNA, we are able to identify an individual through comparing with other DNAs. Criminal justice systems all around the world had ...
From cases such as OJ Simpson to Chandra Levy, DNA profiling also called DNA fingerprinting or DNA typing has played a major role in the criminal justice system. The law enforcement community uses DNA profiling to rule out or identify suspects. Unlike hair microscopy, bite mark comparisons, shoe print comparisons, and firearm tool mark analysis, DNA typing has been developed through massive scientific research and has undergone meticulous scientific evaluation (Innocence Project). DNA is a foolproof method of identifying a perpetrator of a crime.
DNA, otherwise known as Deoxyribonucleic acid, is a fundamental part of our body, providing genetical information to cells, determining our genetic genotypes and visible phenotype characteristics. It also has other uses, such as DNA Fingerprinting. This technique requires a sample of cells, that, through a scientific process, produce a unique pattern to determine a person by. DNA fingerprinting is used in paternity testing, to determine a child’s father, and in forensics and crime solving. The science behind DNA fingerprinting in forensics, and moral dilemmas surrounding it, will be explored and explained.
The scientific and medical progress of DNA as been emense, from involving the identification of our genes that trigger major diseases or the creation and manufacture of drugs to treat these diseases. DNA has many significant uses to society, health and culture of today. One important area of DNA research is that used for genetic and medical research. Our abi...
...ary part in genotypes of potential interest that human geneticists breeders, as well as evolutionary geneticists are investigating. However, although we have the capability to unravel experiments that the founders of quantitative genetics would have never imagined, but their basic, un-computational machinery that they developed is most easily adaptable to the latest analyses that will be needed. We are far from ‘letting-go’ molecular biologists from the mathematical techniques/systems, because this age in respect to genomics has been forced into accepting gratitude due to the major importance of quantitative methods as opposed to the new molecular genetics. As geneticists tend to map molecular variation as well as genomic data, quantitative genetics will be moving to the front position because of its relevance in this age of rapid advancement in molecular genetics.