Ian Wilmut and Cloning
Before Dolly the cloned sheep made news headlines, the same researchers had only the year before raised seven other sheep from oocytes whose nuclei had been replaced with nuclei from either fetal or embryonic tissue.1 This created a minor stir as this is the "first report to [their] knowledge, of live mammalian offspring following nuclear transfer from an established cell line."1 The implications of this is that they have provided techniques to analyze and modify gene functions in sheep (By providing clones of the same sheep).1 The key to their success is the "serum starvation" that the donor cell undergoes, to force the donor cell into a 'quiescent' state, so that it is not replicating its DNA or dividing. This possibly makes the nucleus more susceptible to re-programming by the recipient egg cell.
The researchers built on this knowledge, and carried out a nuclear transfer from cells from the mammary gland of a 6-year old ewe in the last trimester of pregnancy. (instead of fetal or embryonic stem cells). After 277 nuclear transfers, Dolly was born.2 Dolly shows morphological characteristics belonging to the breed (Finn Dorset)that donated the nucleus instead of the oocyte donor or the surrogate mother(Scottish Blackface). Thus erasing any possibility of the birth due to the mating of the surrogate mother with another sheep.
In 1975 Gurdon, Laskey & Reeves showed that nuclei transfer from keratinised skin cells of adult frogs supported growth to the tadpole stage 3. Wilmut's experiment took one step further and managed for the organism(Dolly) to grow to adulthood, thereby confirming that adult cells do in fact contain workable versions of all the genes necessary to produce an entire organism.
Previously there was widespread belief that cells from adult mammals cannot be persuaded to regenerate a whole organism. Now that Wilmut has proven once and for all that this is otherwise, many cloning experiments that were once fantasy could now be accomplished. For example, an organism of interest can be cloned from any living cells from it if it no longer can reproduce normally (perhaps due to defects in gametes formation) or if only cultured cells of the organism of interest remains (it has already died but complete cell death has not occurred).
However, it will take some time before Wilmut's technique is used as an important aid in all manner of biological and biomedical investigations. As forementioned, having to do 277 nuclear transfer just to obtain one living sheep is impractical for most experiments.
Trelease, Jim. "Book Banning Violates Children and Young Adult Freedoms." Book Banning. Ed. Ronnie D. Lankford. Detroit: Greenhaven Press, 2007. At Issue. Rpt. from "Censorship and Children's Books." Trelease-on-Reading.com. 2006.Opposing Viewpoints in Context. Web. 31 Mar. 2014.
Books are banned for many reasons but more times than not it is because of the sensitive information found within the novel that agitates the reader. As long as people have been able to develop their own opinions, others have sought to prevent them from sharing. At some point in time, every idea has ultimately become objectionable to someone. The most frequently challenged and most visible targets of such objection are the very books found in classrooms and public libraries. These controversial novels teach lessons that sometimes can be very sensitive to some but there is much more to challenged books than a controversial topic. What lies within these pages is a wealth of knowledge, such as new perspectives for readers, twisting plots, and expressions that are found nowhere else. For example, To Kill A Mockingbird, contains references to rape, racial content, and profanity that have caused many to challenge the novel in the first place. The book was banned from countless
...etter than ignorance. Book censorship should not limit the amount of knowledge a child can receive, instead, books should be used to benefit children in their education and future career.
School boards and teachers have a responsibility for protecting the minds of their students and covering age appropriate material. However, does this responsibility cover the extreme act of banning books from school classrooms? Does not the teacher have a duty to introduce to their students world issues in order to better the students ability to cope with problems in the world? How does a school decide which books should be banned from the classroom, and should it be left up to the teacher to decide what is decided in his/her classroom. By banning books from the classroom, we prevent our students from learning about controversial topics in a safe environment, and we also encroach upon the student’s freedom of reading what they want in school.
When a book is banned, reasoning should be backed up with many facts and teachers should be able to agree or disagree. Teachers are the ones who have graduated from colleges and have earned this right. Though the opinions of parents matter, their opinion does not necessarily take into account all that the book has to give. Parents may not see the potential of the book as a whole. They may just see the racist language or cruel behavior in a book. What their opinions are mostly based on is the information that will keep everyone the most comfortable instead of the importance behind the basics for students to learn (Hills). Some books may include opposing ideas like this, but that does not mean that they do not have something to teach us. Many teachers take it on themselves to determine what is appropriate. They take on a certain level of self-imposed censorship to make sure that they are teaching appropriate material. Along with this, books being bought with school funds have to go through a process of approval (Zimmerman). This should eliminate any problem areas that parents may have. Besides just having the school board approving the books, many teachers have the same basic outline of what a book should include and be like. They ag...
...in high school and are normally subjected to crude language and sexual content throughout the day, so this would also give them a better understanding of the book. Banning of certain books help protect children from the evil ways of the world that they should not see until an older, more mature age. The cruel language and violence within this book may influence children to act out and may possibly alter their future.
People should be allowed to read whatever they want to read, even if it is a touchy subject to someone else. Although some people mainly believe in the banning of books due to explicit content, it actually causes a negative effect on people and children. Not only does it take away the people’s first amendment rights, but it also shelters children from real life situations that might affect their future. Banning books is unconstitutional and shelters children.
Although some may say that certain books contain graphic/violent content, banning such books is not an effective method to prevent young children from being exposed to such content, and therefore is unnecessary. One person that harbors such beliefs is Christina Healey. In her article “Book Banning can be Justified in Some Cases,” she argues that in some cases, book banning is...
Philosophers have struggled with determining the proper role of government. In the absence of government and laws, people could do whatever they wanted, and some of them would try to slaughter others and steal their property. This is the state called anarchy. People have realized that the safety of the people and the country would be in jeopardy in such a state. Thus, it is necessary for a country to have a government and/or ruler. However, a ruler must not have absolute power nor lack authority. But the protection of the people and the country alone is not enough for a country to prosper. The property and the natural rights of the people and the government must also be protected. Thus, the proper role of government is to protect the people’s natural rights, their property, and the people themselves.
This is explained by Craig Freudenrich. He discusses this on the website HowStuffWorks. Freudenrich tells of how Ian Wilmut and his colleagues successfully cloned Dolly the sheep at the Roslin Institute in Midlothian, Scotland. Dolly the sheep was the world's first successfully cloned mammal, cloned from an adult somatic cell. He writes how after Dolly, scientist have been cloning animals like cows and mice. “They rely on transplanting the genetic information from a specialized cell into an unfertilized egg cell, whose genetic information has been destroyed or physically removed.” (How Cloning Works) This information is very enlightening to anyone who questions how cloning works. Furthermore it secures the information needed to inform the general public of what they need to know to have a responsible and appropriate
Some people may argue that students should have a right to read what they prefer because we are denying them of their first amendment freedoms of the press and freedom of speech. No book should be banned due to improper themes in them. Books are a gift in which authors can express their opinion and beliefs and we can read about them. Kids should be able to be open minded to all books, banning books won’t affect you but it’ll affect children, which is what many
Cloning is a recent innovative technique the National Institute of Health defines as a process employed to produce genetically identical copies of a biological entity. Depending on the purpose for the clone, human health or even human life can be improved or designed respectively. “Somatic cell nuclear transfer (SCNT) is the most common cloning technique. SCNT involves putting the nucleus of a body cell into an egg from which the nucleus has been removed."^1 From this technique, an embryonic cell is activated to produce an animal that is genetically identical to the donor. Today, human cloning still remains as a vision, but because of the success of Dolly, the lamb, researchers are becoming more confident in the ability to produce a genuine
...out of jail Ophelia lets him stay at her apartment until he gets his job and house back. She trusts him to be there and not steal anything even when she’s not there. After awhile their connection grows and they begin to actually like each other. Ophelia does not care if he’s rich or poor she likes him for who he is unlike Penelope.
First, cloning has a long history dating back thousands of years, which has allowed the process of cloning to evolve to more complex organisms. Cloning was first experimented with different plant offspring (“Cloning” n.p.). The cloning process of plants in the past was very simple and only required parts of the plant such as roots, stems, and leaves to be cut and planted, which would grow into an exact copy of the initial plant (“Cloning” n.p.). In the 1950s, scientists were able to successfully clone frogs in a more complex manner by transferring the nucleus from a tadpole cell to a frog egg that had already had its nucleus (“Cloning” n.p.). Scientists later discovered that their cloning procedure was a success when the frog that grew from the egg experimented on had the same genetic makeup as the tadpole that donated a nucleus from one of its cells (“Cloning” n.p.). Dolly the sheep is the product of the first successful cloning of a mammal (“Cloning” n.p.). “In 1997 Scottish scientist Ian Wilmut and his colleagues announced the birth of a clone of an adult mammal” (“Cloning” n.p.). Dolly was created from a cell of a breast gland from an adult sheep was put in an embryo and placed inside a sheep able to give birth (“Cloning” n.p.). Dolly was born looking identical to the shee...
...ellent policies, 5) the Constitution had come into existence through the working together of various groups that had composed South Africa, 6) South Africa's political and economic institutions are well established, 7) and that South Africa is by far the most developed country in Africa. However, there are still avenues that can impede further progress, more so economically then politically. Primarily the lack of foreign investment, especially when South Africa's gold and diamond reserves are emptied as other parts of economy are not as developed. Secondly, the economic gap between whites and blacks that was stretched during the time of apartheid needs to be tightened or else it could become dangerous to the stability of the political system. However, due to the leadership of Nelson Mandela, South Africa’s current government structure exists to solve these issues.