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Pathophysiology of acute renal failure
Patho-physiology of acute renal failure
Pathophysiology of acute renal failure
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Recommended: Pathophysiology of acute renal failure
When a client arrives in the emergency room with complaints of asthenia, malaise, headache, weight gain, and decrease in urination, the key factor is urine retention. That clue alone may lead to a diagnosis of acute renal failure. Acute renal failure is the loss of the ability to filter, remove, and balance fluid and electrolytes in your body. There are three types of causes, all of which have a necessary plan for treatment.
Prerenal
Prerenal is the disruption that occurs before reaching the kidneys, and are usually caused by inadequate blood circulation. It prevents blood from reaching the kidneys to be filtered. According to Remedy’s Health Communities (2001), “Some notable causes of prerenal ARF are dehydration, heart failure, sepsis (severe infection), and severe blood loss.” Pre-existing medical conditions can also be associated and factor into the cause. For example, atherosclerosis (hardening of the arteries with fatty deposits), can reduce blood flow (Remedy's Health Communities, 2011). Not getting the proper amount of fluids may cause an ambulance and lead to a prerenal ARF. The use of diuretics can flush out large amounts of fluids, also dehydrating the patient and causing an imbalance in fluid and electrolytes. Patients who have heart conditions take diuretics to prevent other problems and that puts them at a higher risk for prerenal problems. A few other risk factors may include hemorrhage, cardiac dysrhythmias, anaphylaxis, and embolism.
Intrarenal/Intrinsic
This acute renal failure occurs within the kidneys. As said by Remedy’s Health Communites (2001), “Intrinsic ARF accounts for approximately 40% of the cases of acute renal failure.” Three classifications of intrarenal ARF are vascular disease, disease of tubules ...
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...take and output, weight loss, stable vital signs, normal breath sounds, and no distended jugular veins.
These goals will help with the patient’s symptoms and eventually allow increased urination.
Reference List
Diet Health Club. (2014, January 14). Retrieved from http://www.diethealthclub.com/health-issues-and-diet/acute-renal-failure/acute-renal-failure-diet.html
M.D., K. L. (2012, December 5). American Journal of Nephrology. Obesity and kidney transplant candidates: how big is too big for transplantations?, 11.
MALAY AGRAWAL, M. (2000, April 1). American Family Physician. Retrieved from http://www.aafp.org/afp/2000/0401/p2077.html
Medline Plus. (2011). Retrieved from http://www.nlm.nih.gov/medlineplus/ency/article/000501.htm
Remedy's Health Communities. (2011, May 1). Retrieved from http://www.healthcommunities.com/acute-renal-failure/overview-of-arf.shtml
Examination revealed an oxygen saturation of 98% and blood pressure of 145/90. Oropharyngeal inspection revealed significant crowding (Mallampati class 3) with macroglossia. Chest auscultation was clear and two heart sounds were audible with nil else.
There are two types of glomerulonephritis—acute renal failure (ARF) and chronic kidney disease (CKD). The ACF form generally develops suddenly as a result of an infection or illness, such as, group A streptococci bacteria, hepatitis, or in diseases such as lupus or HIV (Mathias, 2013). This type may require dialysis to replace renal function while it lasts, however, kidney function usually returns after the primary illness is treated. Many acute patients will not have any other complications as no permanent damage is done. Whereas CKD is found in a person that has had glomerulonephritis for months to years in some cases and may be asymptomatic until the kidney has become irreversibly damaged. ARF can evolve to become chronic if the glomeruli do not respond to
The kidneys play a major role in the blood composition and volume , the excretion of metabolic wastes in the urine, the control the acid/base balance in the body and the hormone production for maintaining hemostasis. The damages to the GBM in the glomeruli alter filtration process that allows the protein and red blood cells to leak into the urine. Loss of protein like albumin in the urine results in a decrease of their level into the blood stream. Consequently, this patient’s blood reveals a decreased albumin (Alb) value of 2.9 g/dL, decreased serum total protein value of 5 .0 g/dL and in the urine presents of the protein and the RBCs. Impaired filtering capacity result in inability of kidneys to excrete excretory products like electrolytes and metabolic waste products that will then accumulate in the blood. Furthermore, inability of distal convoluted tubules to excrete sufficient quantities of potassium, sodium, magnesium (Mg), chloride (Cl), urea, creatinine (Cr), alkaline phosphatase (Alk Phos), and phosphate (PO4) results in their elevation in the blood. His laboratory values reveal an increased of sodium value of 149 meq/L, an increase of potassium value of 5.4meq/L, increased chloride value of 116 meq/L, increased blood urea nitrogen (BUN) serum of 143 mg/dL, and increased creatinine serum of 7.14 mg/dL. The other abnormal blood tests associated with a loss of kidneys’ filtration property identify in this patient are related to an increase of alkaline phosphatase value of 178 IU/L, increased magnesium value of 3.8mgdL, and increased phosphate (PO4) value of 5.9 mg/dL .
Being overweight or obese are risk factors for many chronic health conditions such as heart disease, diabetes, and … cancers.”
1 in 3 Americans Adults are currently at risk for developing kidney disease. What is acute renal failure, when your kidneys functions all of a sudden stop working and your kidneys are the body’s filter which remove waste products and help balance water, salts and minerals especially electrolytes in your blood when your kidneys stop working you end up building all the products in your body that need to be filtered and eliminated. The pathophysiology of Acute Renal Failure are due to three main causes Pre-renal, Intra-renal, and Post renal. Pre-renal is a sudden drop in blood pressure or interruption of blood flow to the kidneys from illness or sever injury. Intra-renal is direct damage to the kidneys by inflammation of drugs, infection, toxins or reduced blood supply. Post-renal is a sudden obstruction of urine flow because of enlarged prostate bladder tumor, kidney stones, or injury.
Weitz, J., Koch, M., Mehrabi, A., Schemmer, P., Zeier, M., Beimler, J., … Schmidt, J. (2006). Living-donar kidney transplantation: Risks of the donor- benefits of the recipient. Clinical Transplantation , 20 (17), 13-16.
The renal disease are common nowadays .The acute renal failure is a medical term means that the kidneys stopped from working and not able to clear toxins from body ,not able to maintained a stable electrolyte balance inside the body and not able to secret the extra fluid as urine outside the body. The renal replacement therapy (RRT) or dialysis has been discovered on 1913 by Able, Rowntree and Turner in London, UK.
Ogden, C.L., Carroll, M.D., Kit, B.K., & Flegal, K. M., (2012). Prevalence of obesity and
Obesity is now considered a global epidemic, with particularly concentrated numbers in the United States. In 2011-2012 more than one-third of U.S. adults were estimated to be obese (National Center for Health Statistics, 2013). Due to the increasing prevalence of the epidemic, anesthesiologists must manage a significant number of clinically obese patients. A large range of physiological variations are associated with obesity, including cardiac, respiratory, and metabolic functions (Leykin, v). The areas of concern for anesthesiologists when operating on the obese can be separated into three perioperative stages: preoperative, intraoperative, and postoperative.
Obesity has become a very critical problem in the United States. According to the Centers for Disease Control and Prevention (CDC, 2011) in the past two decades there has been an increasingly dramatic increase in obesity seen within the United States. Evidence from research indicate a strong correlation between being over-weight or obese with incidences of coronary heart disease, type 2 diabetes, hypertension and cancers increases (CDC, 2011). A major complication associated with diabetes is the occurrence of nephropathy which can lead to end stage renal disease (ESRD).
This article is for people whose kidneys fail to work. This condition is called end-stage renal disease (ESRD).
If the patient has a urinary catheter, and most ICU patients do, he or she may not have any reportable symptoms. Therefore, good assessment of urinary elimination, done in relation to a patient’s signs, symptoms, urine amount, intake and output, and lab values, is important. The lab values are discussed in Chapter 5. Acute and chronic renal failure can cause numerous systemic symptoms and altered homeostasis ( Collins, 2011). See Table 3-10 for abnormal urinary elimination.
Cardiovascular System: He does not experience any chest pain or palpitation. He does not have dyspnea or leg swelling.
The kidneys are organs that play an important role in the urinary system. At the site of the glomerulus, waste products and water filter into the proximal convoluted tubule and go through the urinary system. Blood and proteins are not able to bypass the filtration system. They go from the afferent arteriole, into the glomerulus and then leaving in the efferent arteriole (Figure 1). Some people have problems with their filtration system and develop nephrotic syndrome. This is when the kidney filter is damaged and allows numerous amounts of proteins to bypass into the proximal convoluted tube. This reduces the amount of proteins that are in the bloodstream. Proteins are used to keep fluid in the bloodstream. Without it, the fluid can leak out into the tissues and cause swelling which is also called edema (Figure 1).
Chronic Kidney Disease. Mayo Foundation for Medical Education and Research, 2014. Web. 20 May 2014.