Vasculitis refers to a heterogeneous group of disorders that is characterized by inflammatory destruction of blood vessels. Inflamed blood vessels are liable to occlude or rupture or develop a thrombus, and thereby lose the ability to deliver oxygen and other nutrients to tissues and organs. Depending on the size, distribution, and severity of the affected vessels, vasculitis can result in clinical syndromes that vary in severity from a minor self-limited rash to a life-threatening multisystem disorder
until several years later in 1936, that three more cases were discovered. A German pathologist, Friedrich Wegener described and found this disorder as a distinct form of Vasculitis, a rare blood vessel inflammation that since the 1950’s has been called Wegener’s Disease Granulomatosis. (http://www.hopkinsvasculitis.org/types-vasculitis/wegeners-granulomatosis/2016) In 1989, the American College of Chest Physicians awarded Wegener a “Master Clinician” prize, a year before he died. However in 2000, the
Polyarteritis Nodosa is a vasculitis disease that affect medium muscular arteries. Vasculitis is a disease that attacks the blood vessels that make arteries become inflamed. Polyarteritis Nodosa is a rare disease that affect adults, mainly middle ages males. The cause of the disease is unknown but has been related to hepatitis B or C. Organs that are mainly affect is the heart, kidneys and skin. Signs and symptoms are general such as fever, fatigue, loss of appetite and weight loss (Gota). Diagnosing
the patients. Neurological manifestations of APMPPE include Headaches being commonest while others are paraesthesias, vertigo, psychosis and more severe complications, Cerebrospinal fluid pleocytosis stroke and cerebral vasculitis.(3, 4) Association of APMPPE with systemic Vasculitis in the patients with positive perinuclear antineutrophil cytoplasmic antibody has been reported.(5, 6) Other systemic inflammatory diseases suggesting an underlying immune mediated or an inflammatory mechanism include
a “multisystem vasculitis that results in localized coronary artery elastin breakdown and aneurysm formation,” (Lau). This simply means it is a condition that causes inflammation of blood vessel walls in the body. Kawasaki disease is also referred to as “mucocutaneous lymph node syndrome,” by Black’s Medical Dictionary, (Marcovitch). It is most prevalent in infants and toddlers, “mainly in children under five,” (Marcovitch). “Kawasaki disease (KD) is an acute, systemic vasculitis in children, with
include marked bacteremia and lymphocyte destruction in the spleen and mediastinal lymph nodes. Rabbits and guinea pigs rapidly develop fulminate systemic disease, and pathologic findings often include necrotizing lymphadenitis; splenitis; pneumonia; vasculitis; and hemorrhage,
Connective Tissue Connective tissues are found all over our bodies. Generally, they are located in blood, fat, and between muscles and bones. The matrix is the substance that surrounds the cell. Matrices can be fluid or solid, depending on where they are found. They also are found to have varying degrees of vascularity. For example, a bone would be very vascular while cartilage is avascular. Two good property the cells of connective tissue have is that they can divide and repair themselves
triggered by respiratory illnesses from winter. HSP was first noted in 1801 by Dr. William Heberden, a london physician, who made case notes on a young boy aged five that was displaying, what we know to now be, typical HSP symptoms. HSP is a type of vasculitis, or inflammation of the blood vessels, that targets mainly children between two and thirteen years old. The disorder itself is rare, and recurrence even more rare, with adults showing much more severe symptoms than children on average. If untreated
The geographic location of the patient is important in the diagnosis of monkeypox, as the disease usually occurs in remote villages in the tropical African rain forests. Differentiation from chickenpox is important; the latter appears in successive crops so that lesions at various stages of development are visible at any time. In contrast with smallpox, the distribution of chickenpox is 'centripetal' with more lesions on the trunk than on the face and extremities. For definitive diagnosis, scabs
I have chosen to do my essay on the largest organ of the body, skin. It has several functions vital to the survival of the body as I will discuss in the following paragraphs. The skin is an elastic covering that protects the body against exposure to dangers within our environment and makes up 15% of the weight of the body. It minimizes water loss, repels water and protects underlying structures. The dermis has blood vessels that are close to the surface to allow blood to flow and reduce the temperature
the inflammatory compounds, play an important role in the development and aggravation of ischemic stroke. The different ways that an inflammatory environment can contribute to the stroke development are: alteration in the vascular reactivity or vasculitis, thus promoting vasculopathy; thrombosis and atherosclerosis (ref 11, 15, 18-22 macrez). Even though there are various types of immune cells (macrophages, monocytes and T cells, etc) contributing to the development of stroke the focus of this review
Lupus is a chronic inflammatory disease that occurs when your body’s immune system attacks healthy tissue and organs. This inflammation can damage many different bodily systems. Lupus commonly affects the joints, skin, kidneys, lungs, brain and heart. Many people with lupus have found relief for some of their chronic pain through practicing a few different styles of yoga. Symptoms Of Lupus Lupus is often hard diagnose because the symptoms mimic other disorders. The most distinctive sign of lupus
The Kawasaki syndrome or disease was named after a Japanese pediatrician named Tomisaku Kawasaki who was the first to described the illness in medical literature in 1967. The Kawasaki syndrome, also known as the Mucocutaneous lymph node syndrome, is a very rare autoimmune disease that most commonly affects children usually under the age of five. Older children and those who are in their teenage years can also get this disease but it is very uncommon. Cases of the Kawasaki syndrome is often diagnosed
Multiple Sclerosis (MS) is a debilitating disease that affects approximately 400,000 Americans. It occurs two to three more times in women than in men and is most prevalent in women in their early thirties which makes researcher believe hormones play a significant role in developing MS. Patients can go through periods of relapse and remission with the possibility of the symptoms getting progressively worse with each occurrence. Statistics show that eighty percent who have MS will live twenty or plus
CAD may cause permanent damage to myocardial cells or infarction. The left ventricle of the heart is most susceptible to CAD. The causes of CAD include atherosclerosis, congenital defects, coronary artery spasm, dissecting aneurysm, infectious vasculitis and syphilis. Atherosclerosis and vasospasm are the most prevalent causes of CAD, with atherosclerosis being the most common. Pathophysiology Atherosclerosis Atherosclerosis is the hardening of the arteries. It occurs when fat, cholesterol and
Title of Case: Etiology and treatment of pericardial tamponade. Background: While in the SICU, I was involved in the care of a patient that presented with pericardial tamponade. He subsequently underwent a pericardiocentesis and a pericardial window. I was interested in the specific causes of pericardial effusions/tamponade as well as the incidence of each cause. Furthermore, I was interested in the treatment of cardiac tamponade. Specifically deciding between pericardiocentesis versus pericardial
The beauty industry, a $265 billion dollar global market of products such as cosmetic appliances and services like plastic surgery grows exponentially each moment (The history of the beauty industry, 2014). As an individual's appearance escalates in importance, cosmetics play an increasingly crucial aspect in a person’s self-perception. In fact, even individuals aware of detriments like cutaneous deformities and neurological impairments use cosmetics because of potential leverages that come in the
are at a healthier standpoint by taking the vaccine while in actuality individuals may be at more harm by taking the vaccine versus having the virus. Firstly, Merck admits that the MMRII vaccine can cause serious life threaten conditions such as Vasculitis (inflammation of the blood vessels), Pancreatitis (inflammation of the pancreas), Diabetes, Thrombocytopenia (low blood platelet count), Chronic arthritis, Encephalitis (inflammation of the brain), and Panniculitis (inflammation of the subcutaneous
I am a warrior, fighter, and a child of God. I have fallen into very dark places in my life. No one thought I’d be able to make it through. Yet, I proved them wrong, and inspired others to work hard. Having someone remind us the importance of faith, will lead to goodness. Sometimes, we will be placed in difficult situations where we need someone to remind us of God’s word. I’ve struggled to reach to a point of confidence, and determination. For most of my childhood years, I was a subordinate. It
inflammation threatens to damage critical body organs, steroids can be organ saving and, in many instances, life-saving. For example, they may help prevent the progression of kidney inflammation, which can lead to kidney failure in people who have lupus or vasculitis. For these people, steroid therapy may eliminate the need for kidney dialysis or transplant” (Steroids to Treat Arthritis). Steroids can help people have the need to not get a transplant or dialysis. “When taken in these very high doses, anabolic-androgenic