“Huntington's disease (HD) is the result of a genetically programmed degeneration of brain cells, called neurons, in certain areas of the brain” (NINDS). The condition has been named after George Huntington, the finding physician who first discovered ands defined it in the late 1800s.The flawed gene code shows a blueprint for a protein called huntingtin (Huntington's Disease). This protein’s role is not yet known, but it's called "huntingtin" do to the doctors that linked it as a defective form and the cause of Huntington's disease. The faulty huntingtin protein leads to changes in the brains functional process, this genetic anomaly which is caused by a defect in the gene of chromosome 4. The imperfection creates a part of DNA, called a “CAG trinucleotide repeat” to occur more times than normal. This section of DNA would normally repeat ten to twenty eight times. Huntington disease carriers on the other hand show it repeated thirty six to one hundred and twenty times” (A.D.A.M. Medical Encyclopedia). Those with Huntington disease will develop spontaneous jolting or jerking movements identified as chorea (Huntington disease. 2014.).
The degeneration of these cells causes uncontrollable actions, a loss of rational abilities, and emotional disorders. Huntington disease is hereditary, which means it is passed from the host parent (father or Mother) to the child by way of a mutation in a gene. Every child with Huntington disease parents has a fifty-fifty chance of receiving the Huntington disease gene (NINDS). In children who do not inherit the gene will not develop the mutation and will not pass it on to following generations. Children born that do inherit the Huntington disease mutation gene will sooner or later develop the disease...
... middle of paper ...
...ntington disease. Retrieved May 23, 2014, from http://www.ncbi.nlm.nih.gov/pubmedhealth
Huntington disease. (2014, April 20). - Genetics Home Reference. Retrieved May 23, 2014, from http://ghr.nlm.nih.gov/condition/huntington-disease
Huntington's Disease. (n.d.). Alzheimer's Disease and Dementia. Retrieved May 23, 2014, from http://www.alz.org/dementia/huntingtons-disease-symptoms.asp
Huntington's Disease Research at The Johns Hopkins Hospital. (n.d.). Huntington's Disease Research at The Johns Hopkins Hospital. Retrieved May 25, 2014, from http://www.hopkinsmedicine.org/psychiatry
NINDS Huntington's Disease Information Page. (n.d.). Huntington's Disease Information Page: National Institute of Neurological Disorders and Stroke (NINDS). Retrieved May 22, 2014, from http://www.ninds.nih.gov/disorders/huntington
The symptoms of Huntington’s disease increase slowly and last until death. Chorea is one of
kcals. At the time of admission there were essentially no differences in the type of
Huntington’s disease (HD) is a progressive autosomal dominant neurodegenerative genetic disorder. HD was originally named Huntington’s chorea after Dr.George Huntington, an American physician who first gave a detailed note on the symptoms and course of the disease in 1872.Recently the name has been changed to Huntington’s disease to emphasize the fact that chorea is not the only important manifestation of the disease but several non-motor symptoms are also associated with this disease.[1]
Huntington's disease is a progressive brain disorder that is caused by a single defective gene on chromosome 4 — which is one of the 23 human chromosomes that carry a person’s entire genetic code (alz.org, 2013). This defect is dominant, w...
It is estimated that between .1 and 10 % of people who suffer from Huntington's
Huntington’s disease is named after George Huntington. This disease genetically is an inherited disorder that damages the mind and nervous system. This may affect actions of the body for example like movement, the ability to reason, awareness, and thinking and judgment. It can also affect their behavior. The word genetic is that the disorder is delivered on by each generation of offspring by special codes called genes(Patient.Co.Uk, 2011). Genes are relocated from a parent to offspring and is held to decide some characteristics of the children (Patient.Co.Uk, 2011).
Dementia can occur in relation to many different illnesses. Some of the most common of which are Huntington’s Disease,
Huntington’s disease is a progressive neurological disorder that is caused by an autosomal dominant mutation in the HTT gene. There will be no change in the allele frequencies because this treatment only has an effect on the phenotype, not the genotype; it does not
Huntington’s disease (HD), also known as Huntington chorea, is an inherited disorder that causes the death and break down the nerve cells in the brain. This genetic disorder is a late onset in life, except for the rare occurrence of this disease, called juvenile huntingtons. Symptoms usually start appearing in people between the ages of thirty and fifty years old. However, if the symptoms become present before the
I looked up Huntington’s Disease to find out more about the disorder. There is no real treatment for the disorder, so I do not see any benefit of knowing that you are going to develop the disease. I feel the distress of knowing that a gene is present and the disease is going to come in time would be worse than the symptoms starting to manifest themselves. The early symptoms can develop any time, but in most cases, they develop in between the age range of 30 – 50 years of age. The initial signs and symptoms are very subtle causing problems with coordination, involuntary movement, and memory. The person affected may develop depression or irritable moods. In the early stages, there are some medications that can help with those symptoms.
Huntington’s disease is an inherited condition in which nerve cells in the brain break down over time. No cure exists for the disease, but drugs, physical therapy, and talk therapy can help manage some symptoms. Testing is done by blood sample. The genetic test analyzes DNA for the HD mutation by counting the number of repeats the Huntington gene made. Part of the gene repeats itself over and over again like a stutter. The results are near 100% accurate. The disease appears around age 40.
Huntington’s disease is caused by an abnormal dominant gene. Also called Huntington’s chorea, it is a complex disorder that affects a person capability to feel, think and move. The symptoms of Huntington’s disease consist of mood swings, irritability, depression, and anger. These symptoms are likely to worsen and the disease a lot of times runs in the family. If people have at least one parent with Huntington’s disease, the chances of them inheriting it are 50-50 chance. There is also a 50-50 chance that, that same person could pass the faulty gene on to their future child. This pattern of inheritance is called "autosomal dominant". The disease could also affect a person’s judgment and other mental functions. In some cases the person could
It's 6 a.m. and your alarm clock goes off. For most people you get up and get ready. When you have Huntington's disease it makes simple things much more difficult. A life with Huntington's disease would be a challenge.
Huntington’s is a disease that is caused by a genetic defect on chromosome 4. This defect causes the CAG repeat to occur more than it’s supposed to. This section of DNA is repeated 10 to 28 times in a normal person but a person with Huntington’s it’s repeated anywhere from 36 to 120 times, depending on how severely their affected. This is an inherited disease that causes a progressive degeneration of the nerve cells in the brain which affects many aspects of a person such as their behavior, movements, cognitive thinking, and causes several other problems.
Huntington’s disease is a progressive, fatal, neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin gene, which encodes an abnormally long polyglutamine repeat in the huntingtin protein Huntington’s is a disease that advances very slowly over a lifetime, it is hereditary. HD is a disorder that causes changes in the brain. Which affect mobility, mood and the ability to think clearly. Each year about two thousand people are diagnosed with HD. One thousand fifty people are at risk to get this disease in the United States alone. There is a worldwide occurrence of HD, but the lowest is Japan (Ross, 2011).