Stem Cells

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What is a stem cell?
Stem cells have the ability to divide for indefinite periods in culture and to give rise to specialized cells. They are best described in the context of normal human development. Human development begins when a sperm fertilizes an egg and creates a single cell that has the potential to form an entire organism. This fertilized egg is totipotent, meaning that its potential is total. In the first hours after fertilization, this cell divides into identical totipotent cells. This means that either one of these cells, if placed into a woman's uterus, has the potential to develop into a fetus. In fact, identical twins develop when two totipotent cells separate and develop into two individual, genetically identical human beings. About four days after fertilization and after several cycles of cell division, these totipotent cells begin to specialize, forming a hollow sphere of cells, called a blastocyst. The blastocyst has an outer layer of cells and inside the hollow sphere, there is a cluster of cells called the inner cell mass.
The outer layer of cells will go on to form the placenta and other supporting tissues needed for fetal development in the uterus. The inner cell mass cells will go on to form virtually all of the tissues of the human body. Although the inner cell mass cells can form virtually every type of cell found in the human body, they cannot form an organism because they are unable to give rise to the placenta and supporting tissues necessary for development in the human uterus. These inner cell mass cells are pluripotent — they can give rise to many types of cells but not all types of cells necessary for fetal development. Because their potential is not total, they are not totipotent and they are not embryos. In fact, if an inner cell mass cell were placed into a woman's uterus, it would not develop into a fetus.
The pluripotent stem cells undergo further specialization into stem cells that are committed to give rise to cells that have a particular function. Examples of this include blood stem cells which give rise to red blood cells, white blood cells and platelets; and skin stem cells that give rise to the various types of skin cells. These more specialized stem cells are called multipotent.
While stem c...

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...homson
2. Dr. Gearhart
D. The potential uses of pluripotent stem cells.
1. Better understand human development
2. Testing of experimental drugs
3. Cell Therapies
4. Problems
a.) understanding the basics………
b.) immune system
c.) rejection

E. Adult stem cells.

1.) Myth vs. Fact

F. Some adult stem cells have the same potential as pluripotent stem cells.
1.) Committed, or not?

G. What is wrong with using adult stem cells.
1.) pluripotent stems cells do not exist in adult humans
2.) There are no stem cells for all tissue types in adult humans
3.) An abundance of totipotent cells do not exist in adult humans
4.) IT TAKES TIME TO GROW!

H. Conclusion.

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