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spinal cord case study
spinal cord injury in flashcard
case study of spinal cord injury
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PURPOSE: To inform my audience about people in the United States living with spinal cord injuries
There are about a quarter of a million people in the United States living with spinal cord injuries. In addition, between 7,600 and 10,000 new injuries occur each year. Nearly half of these new injuries will occur in young people between the ages of 16 and 30. I have become very interested in the research to find a cure for spinal cord injuries and hope to share some of the information I found with you today. In order for you to fully understand the details I will be sharing with you, I’d like to begin with a general overview of the spinal cord before moving on to the three stages of research I will cover: past research which has lead to present treatments, recent research, and the present and future research.
The spinal cord is basically a bundle of nerves which runs from the base of the brain to the middle of the waist. It is the core of the spinal column and carries nerve impulses to and from the brain to the rest of the body. When this soft, jelly-like cord is injured, severe effects are felt on the body. The spinal cord can be bruised, damaged, or severed, each resulting in different degrees of injury. In this illustration we see an example of a slipped disk. A slipped disk most often results in severe and sometimes disabling pain and can be treated by painkillers, bed rest, or surgery. While definitely not a minor ailment, the severity of a slipped disk is not very high since the spinal cord is left intact and therefor there is no nerve damage. However, more serious consequences occur when the spinal cord is damaged or severed. This can happen from traumas or diseases, and since we have a limited time, I will focus only on the traumatic causes. The largest contributor to traumatic spinal cord injuries is vehicular accidents, accounting for nearly 48%. Next is falls at almost 21%, followed by violence, sports, and ‘other’. As you can see from this graph, 66% of sports injuries occur in the form of diving accidents, while I am part of the 3.8% of snow skiing accidents.
Now that I have shared a brief overview of the spinal cord and some statistics about spinal cord injuries, we will look at the past research that h...
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...e sclerosis, Parkinson’s disease, diabetes, heart disease, Alzheimer’s, Lou Gehrig’s disease, and spinal cord injuries, and have already been used against certain types of cancer.
The controversy behind the stem cell research has been raging since the first experiments. The United States Congress banned federally supported human-embryo research in 1996, forcing scientists to solicit funding from private sponsors. Since stem cells are harvested from aborted fetuses, the ethical issues surrounding abortion act as a stigma in the public’s view. However, in September of last year, the National Bioethics Advisory Commission concluded that harvesting stem cells from discarded embryos is morally akin to removing organs from dead people for transplant. Stem cell research continues to be very controversial, yet prevalent in the scientific community.
Research in the field of spinal cord injuries has already come very far in only the past decade, and now seems to be on the fast track to finding a cure. Many of the facts and statistics I found while researching this topic were entirely new to me, and I am glad that I had the opportunity to research such an important and relevant subject.
The vertebral column is composed of seven cervical, twelve thoracic, five lumbar, five sacral, and four coccygeal vertebrae. The lumbar vertebrae are numbered from one through five starting with the highest vertebrae, and preceded by the letter L. (i.e. the lowest vertebral body will be represented as L-5) Between the vertebrae of the cervical, thoracic, and lumbar regions are invertebral discs that serve as shock absorbers that allow the everyday movements of the spine. Discs themselves are represented by naming both of their adjacent vertebral bodies (i.e. a lumbar disc is can be identified as L-4 L-5 or L-4,5). The discs are made up of an outer ring of more dense material called the annulus fibrosus. The annulus fibrosus helps to contain the inner gelatinous material called the nucleus pulposes. Upon a stressful movement of the spine, the nucleus pulposes may rupture through the annulus fibrosus posteriorly toward the spi...
The car accident could damage ones spinal cord if it was crushed or hit hard enough. If the spinal cord is severed, the peripheral nerves may detach from the spinal cord. Detachment may lead to pressure applied by other organs or bones. The wreck may cause broken bones that would compress the spi...
...y W.A & Hostler D.P (2006). Comparison of the Ferno Scoop Stretcher with the long backboard for spinal immobilisation. Prehospital Emergency Care.10 (1): 46-51
A persons Spinal Cord is the cord of nervous tissue which extends from the brain and goes all the way down their back in the vertebral canal. It gives off pairs of spinal nerves and carries impulse to and from the brain, it also serves as the centre for initiating and coordination of many reflects acts. Without the spinal cord a person’s body would not be able to maintain its composure and would cave in on its self. An injury to the spinal cord can be catastrophic to the person, many injuries to the spinal cord result in quadriplegia and/or paraplegia and in some cases death. A Spinal Cord Injury can be classed as a complete spinal cord injury (meaning all functions below the injured area are lost even if the
Spinal cord injuries can range from minor, meaning the injured will recover, to very severe injuries that can cause significant damage to someone’s body and self-esteem. Approximately 12,000 people per year experience spinal cord injuries in the United States. 50% of all spinal cord injuries occur between the ages of 16 and 30 and 80% of all spinal cord injuries happen to males. The most common accidents that cause spinal cord injuries are motor vehicle accidents followed by falls, violence and then sports. There are two major types of spinal cord injuries, complete spinal cord injury and incomplete spinal cord injury. Spinal cord injuries can also cause other complications including respiratory, bladder control, skin sensation, circulation problems, muscle tone, sexual health, pain, depression, scoliosis, UTI and spasticity. Complete spinal cord injuries occur when one loses complete feeling and sensation typically resulting in paralysis below the injury. Incomplete spinal cord injuries mean there is still some feeling and movement below the injury site. One can experience different types of incomplete spinal cord injuries including anterior cord syndrome, central cord syndrome, brown-sequard syndrome, nerve cell injuries and spinal contusions. Currently there is no cure for spinal cord injuries. Causes of SCI:
The spinal cord is a major channel in the body where motor and sensory information travels from the brain to the body. It has white matter that surrounds a central gray matter. The gray matter is where most of the neuronal cells are located. Injury to the spinal cord will affect the conduction of information across any part of the spinal cord where the damage is located (Maynard et al., 1997). This will often result in permanent disability of a certain muscle or region of the body (Meletis et al., 2008) and a loss of tissue where the damage is located (Peng et al., 2009). As of now, there is no treatment for spinal cord injury expect for steroids. All steroids can do is provide protect of the spinal cord from secondary injury for specific patients (Peng et al., 2009).
If only 2% of one million trauma victims had a true spinal cord injury that means 998,000 patients received full spinal immobilization that was unnecessary when only 2,000 warranted spinal immobilization. The use of long board spinal restriction as a precautionary measure should be reconsidered.
Recently, two overviews on the management of LBP in primary care, compared between international CPGs, recommended using diagnostic classification (diagnostic triage) to group patients with LBP into one of three broad categories: LBP with significant neurological deficits, specific LBP, and non-specific LBP36,38. LBP with significant neurological deficits is pain that follows a specific nerve root distribution from a compression41 such as prolapsed lumbar disc, spinal stenosis, or surgical scarring42. Specific LBP is due to serious
Radiculopathy can, in actuality, exist without pain—it is more so defined by objective neurologic signs such as loss of sensation and/or motor activity (due to conduction block), weakness, muscle wasting, and loss of reflexes. Similarly, radicular pain can exist in and of itself. Physiologically, radicular pain is typically evoked by ectopic discharges that arise from the dorsal nerve root or its ganglion, and distributes painful sensations along the length of its axon. Etiologies of radicular pain typically involve either compression or irritation of spinal nerve roots, which could be due to numerous causes including disc herniation, formation of osteophytes, degenerative lumbar spondylosis, scar tissue from a previous spinal surgery, foraminal stenosis, thickening of adjacent ligaments, neoplasms, inflammatory conditions (i.e. ankylosing spondylitis, Paget’s disease), and infectious disorders (herpes zoster, Lyme, spinal epidural
Researchers purposely began paralyzing mice by giving them contusions (a type of spinal cord injury caused by great impact to the spinal cord) and injected the sites of damage with a plethora of different stems cells in combination with intensive therapy. This aids in producing a nerve-insulating substance called myelin that can lead to functional improvements in animals with spinal cord injury. Overtime, helplessly paralyzed mouse legs were slowly but surely becoming mobile—which is what led to the current trials we have being tested on spinal cord injury patients today, except testing with mice is undeniably less expensive considering the fact that a mouse’s body being fumbled with doesn’t compare to the significance of a human being who sustained an accidental spinal cord injury. On top of that, these trials have the potential to make “spinal cord injury” a term of the past, but that dream to many could be highly unlikely if medical research facilities don't receive a considerable amount of funding. The average cost of a clinical trial involving stem cells in the U.S varies from hundreds to hundreds of thousands, which could leave a great majority of those victimized by paralysis vulnerable to feeling hopeless as their perpetual medical bills continue to
This is when an individual starts developing spinal pain which can turn out to be severe or chronic when adjacent nerves start are on the receiving end of the pressure, especially if the condition is not given attention early enough.
Stocchetti, N., Pagan, F., Calappi, E., Canavesi, K., Beretta, L., Citerio, G., … Colombo, A., (2004). Inaccurate early assessment of neurological severity in head injury. Journal of Neurotrauma, 21(9), 1131-1140. doi:10.1089/neu.2004.21.1131
It has been reported many common causes of CM and some rare such as brown tumour, secondary to extramedullar intradural plexiform neurofibroma, posttraumatic pseudomenigocele, epidural IgD myeloma, anterior arachnoid cyst, myelopathy due to vitamin B12 deficiency, cervical dystonia mucolipidoses, adrenomyeloneuropathy[9-17](figure 1.). The result, however, is narrowing of the spinal canal and compression leading to damage of the nerves, vessels and spinal
Spinal cord injury (SCI) is a medically complex and life-disrupting condition. SCI is one of the most severe injuries which bring sudden and profound life changes that have global effects (Somers, 1992). According to World Health Organization (WHO) report (2011), word wide 20-40 people per million of populations acquire spinal injury every year. It is estimated that in the United States (US) each year there are about 11,000 new cases of SCI and there are currently about 250,000 persons alive with SCI, because of lack of improvements in medical care and survival. The prevalence of people living with SCI has increased, and it is predicted that there will be greater and greater numbers of older patients with SCI (Spinal cord injury: facts and
Simple musculoskeletal back pain has symptoms of pain in the lumbrasacral area of the back (Jackson & Simpson, 2006). The upper thighs and knees are also known to be affected (Jackson & Simpson, 2006). This pain is usually described as a dull pain (Jackson & Simpson, 2006). Spinal nerve root pain is localised down the leg, and usually continues below the knee and into the feet (Jackson & Simpson, 2006). It has been d...