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Position Paper: Gene Therapy in Humans
Advancements in science and medicine are usually accompanied with a myriad of ethical and moral implications. The fairly recent advancement in genetics called gene therapy is no exception to the baggage of polarizing views that come with new technology. Gene therapy is an extremely hot topic in both the science world and everyday life. New technology, discoveries, and breakthroughs are rapidly occurring in the field every day. The topic of gene therapy in humans is one that is highly debated due to the ethical implications connected to the science. Both sides of the debate have various reasons for their position, but the main factors come down to the ethics of changing someone’s genome and the consequences that accompany the altercations. The two types of gene therapy, somatic and germ-line are seen in different lights. There is more debate over germ-line therapy because the alterations have more consequences than somatic gene therapy. There are many moral and ethical decisions that need to be considered before gene therapy can be widely accepted. Do we have the right to change a person’s genetics, especially before they are born? Do we know enough to confidently insert or delete genes without detrimental consequences down the road? If we have the ability to help people who have disabilities or diseases, is it ethical to withhold and not treat the patient? I believe human gene therapy is a good and useful tool for medicine and needs to be developed because it posses the ability to help and cure people from ailments that degrade their quality of life.
One of the biggest concerns involved in gene therapy in humans is the lack of knowledge and the possibility for consequences later on or i...
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...ring deadly diseases and preventing abortions. In order for gene therapy to one day become effective much more research needs to be done to discover the consequences of altering specific genes. Also the technology of gene therapy needs to be cost effective so people who need help are able to get help. In the end gene therapy in humans needs to come a long ways before it will be widely accepted but there is great potential in the technology and it needs to be pursued.
Bibliography
Anderson, W. F. (1992). Human Gene Therapy. Science, 256 (5058), 808-813. Retrieved from http://ezproxy.ccu.edu:2190/docview/213544223
Waddington, S.N., Kennea, N.L., Buckley, S.M.K., Gregory, L.G., Themis, M., & Coutelle, C. (2004). Fetal and neonatal gene therapy: benefits and pitfalls. Nature, 11, 92-97. Retrieved from http://www.nature.com/gt/journal/v11/n1s/pdf/3302375a.pdf
... fight the disease. It is crucial that regulation be a necessary component of gene therapy research and applications. In hopes that the government can regulate and can receive this treatment, not restricting it to people that has serious genetic diseases. Gene therapy will change the field of medicine from what it is today. As scientist discovers more genes and their functions, the potential of this treatment is limitless. Though gene therapy is an auspicious treatment choice for numerous diseases (including inherited disorders, some types of cancer, and certain viral infections), the procedure remains precarious and is still under study to make sure that it will be safe and effective. Thus government regulators and scientist must take a lead role in adopting a practical approach to address these issues and determining the correct procedures for dealing with them.
Human gene therapy is a method used in the medical field that treats diseases at a molecular level, by solving the source of the problem; our genes. Today, diseases and disorders are commonly treated by solving the symptoms, the surface of the problem. Many disorders and diseases are caused by defective proteins and within those defective proteins are damaged and defective genes. These defective genes can be treated through gene therapy. Gene therapy is not new and has been developed and improved by researchers for the past couple years. Being an experimental technique, gene therapy also has its pros and cons, but so far is showing positive and rising success rates.
Over 40 years ago, two men by the names of James Watson and Francis Crick discovered deoxyribonucleic acid, or DNA. DNA is hereditary material in humans and almost all other organisms (What is DNA?). From this finding, gene therapy evolved. Today, researchers are able to isolate certain specific genes, repair them, and use them to help cure diseases such as cystic fibrosis and hemophilia. However, as great as this sounds, there are numerous ethical and scientific issues that will arise because of religion and safety.
Gene therapy is a technique that uses genes to treat or prevent diseases. It is the process of taking DNA from one organism and inserting it to another. No development in the field of biotechnology has inspired both greater fear and hope in human society than gene therapy. Here is the big question among the people. While this new advancement in gene therapy promotes new hopes to cure life-threatening diseases or help the amputee or physically disabled persons to lead life like a normal human, it also raises questions about morality as well as the adverse effects it may cause in the future society. In our media intensive society, thousands of newspapers and magazines, tv talk shows resound with different points of view about the morality of gene therapy. Proponents of this medical treatment argue that it promises enormous benefits for medicine as well as agriculture and industry. Yet, it has aroused considerable public concern because it is perceived by many as an unpredictable technology.
In this paper, I will negatively expose Walter Glannon’s position on the differentially between gene therapy and gene enhancement. His argument fails because gene therapy and genetic enhancement is morally impermissible because its manipulation and destruction of embryos shows disrespect for human life and discrimination against people with disabilities.
...s of gene therapy is that the mortality rate is very high. This is because Immune system may attack cells and cells may attack vital organs. Furthermore, ethical issues should be dealt in a positive way. The technological institute has to reduce the unnecessary expenses of the treatment. I highly suggest the government investing more money on the development of gene therapy.
So Gene Therapy, being a process solely aiming to heal genetic issues in human beings, is a technology which is desirable for our modern society. If a method can be produced, which cause...
"What's the worst that can happen to me? I die, and it's for the babies," said Jessie Gelsinger as he left for the hospital to receive gene therapy treatment. (Stolberg) People risk their lives everyday in the name of science. One such science that people have recently been drawn to is gene therapy. Although, gene therapy may be new and exciting and it may be helping to find cures to diseases we only dreamed of curing, we have to remember it is dangerous. It needs to be done with much supervision. Every new step we take in the advancement of gene therapy should be thought over because the consequences could reach farther then we ever believed they could. There are so many dangers of the techniques used that can lead to consequences as serious as death. The government imposes many guidelines, and it needs to stay that way. The biggest dangers, however, may be in what is to come.
"The aim is to decrease the fear of a brave new world and to encourage people to be more proactive about their health. It [Gene therapy] will help humans become better physically and even mentally and extend human life. It is the future” (Hulbert). Dr. Hulbert, a genetic engineer, couldn’t be anymore right; more time, money, and research needs to be put into gene therapy and genetic engineering, since it can cure certain illness and diseases that are incurable with modern medicine, has fewer side-effects than conventional drugs or surgery, and allows humans to be stronger physically and mentally at birth. Gene therapy or genetic engineering is the development and application of scientific methods, procedures, and technologies that permit direct manipulation of genetic material in order to alter the hereditary traits of a cell, organism, or population (NIH). It essentially means that we can change DNA to make an organism better. Genetic engineering is used with animals and plants every day; for example with genetic...
Gene therapy is a technique used in attempts to cure or prevent genetic diseases at the molecular level (basically at the source) by correcting what is wrong with defective genes, a good version of the defective gene is introduced into the existing cells. This technique is still considered experimental, only being done through clinical trials. This idea was first suggested during the 1950’s. The basic idea was “if the basses can be arranged incorrectly then why can’t they be rearranged in the correct way?”
Since its inception, gene therapy has captured the attention of the public and ethics disciplines as a therapeutic application of human genetic engineering. The latter, in particular, has lead to concerns about germline modification and questions about the distinction between therapy and enhancement. The development of the gene therapy field and its progress to the clinic has not been without controversy. Although initially considered as a promising approach for treating the genetic of disease, the field has attracted disappointment for failing to fulfil its potential. With the resolution of many of the barriers that restricted the progress of gene therapy and increasing reports of clinical success, it is now generally recognised that earlier expectations may have been premature.
Genetic Engineering in humans is a highly controversial topic of discussion. The possibilities that it offers to new medical worlds is groundbreaking, but what are the risks? This is a frequently asked question, presenting valid arguments from both perspectives. Like many Biological predicaments, ethical issues tend to clash with that of unseen medical possibilities, resulting in debates and discussions continuously unfolding on the controversial issue.
According to an article titled “Genetics is the Future of Medicine” by Joseph D’Allegro, gene therapy is in the line-up for tomorrow’s medicine. Once the human Genome Project has been completed, the data will be used to understand genetic disorders better. Once this is completed, information from genetic tests will become part of people’s medical records. However, the data uncovered in this testing will only be able to say whether or not someone is predisposed to genetic conditions, not whether the person will actually show symptoms of the disease. Today, gen...
Gene therapy gives patients who born with diseases that are incurable to traditional medicine a permanent cure. If patients received germ-line therapy, which involves replacing disordered genes in sperms or eggs, their offspring would also have correct gene orders. The positive effect would influence the whole family.
Due to the fact that the field of biotechnology is very serious and potentially dangerous, rules must be set down in order to keep the research in check. The high risk research of genetic therapy needs guidelines that have to be followed in order to keep the study just. The articles that are discussed in this essay focus on ethical issues and ideas that should be followed in the field in order to keep research safe and valid.