Pain Management: Management Of Postoperative Pain

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A. Management of Postoperative Pain:
Postoperative care encompasses a majority of the time spent during hospitalizations following prolonged operations. One of the main goals of postoperative care includes pain management as improved pain control may shorten the hospital course125-129. Optimum postoperative analgesia results in earlier ambulation and rehabilitation postoperatively.130-132 Additionally, patient satisfaction greatly improves. Optimal control of pain occurs through the use of multiple analgesics that act on different receptors within the nervous system, a term deemed multimodal analgesia133. Various neurotransmitters exist and the ability to target each aims to minimize the effects of individual agents133. In addition to different classes of drug therapy, the anesthesiologist employs regional anesthetic techniques to help reduce pain via neuropathic transmission.
Although the mainstay of postoperative pain control requires opiate therapy, other classes of drugs help to reduce opioid consumption and their side effects when utilized. Non steroidal anti-inflammatory drugs (NSAIDs) inhibit the synthesis of prostaglandins at periphery, one of the main causes of the heightened pain state. Acetaminophen also inhibits cyclooxygenase and possesses mild if any anti-inflammatory properties. Furthermore, gabapentin and pregabalin target a neuropathic component through GABA and voltage gated calcium channels. Lastly, ketamine acts on multiple pain receptors, the most important being the NMDA receptor. Each of these drugs decrease opioid consumption and improve analgesia by targeting differing pain receptors134-143.
Within the opioid related side effects, preventing postoperative nausea and vomiting, avoiding excessive sedation...

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...nitial preoperative evaluation, intraoperative management to postoperative pain management, aspires to improve surgical outcomes through reduced morbidity and mortality. Communication between the surgeons and anesthesiologists about preoperative risks and perioperative management plans is extremely important in reoperative surgery. Vigilance of the anesthesiologist, via meticulous attention to perioperative details, helps to improve surgical outcomes and further decrease perioperative morbidity such as surgical site infections, cardiac complications, and fluid overload. The issues highlighted within this chapter are not all inclusive. The importance of perioperative optimization and communication concerning care plans to achieve the best outcomes for patients cannot be emphasized enough and requires daily cooperation amongst all parties involved with patient care.

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