Zaltrap Case Study

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Moreover, some of the new drugs being introduced at such large prices have only slight marginal improvements over the already pre-existing drugs. One example of this would be Zaltrap, a drug approved to treat colorectal cancer. Zaltrap was discovered by Regeneron, an emerging biopharmaceutical company, but sold by the French drug maker Sanofi. Yet it worked no better in clinical trials than Roche’s cancer drug called Avastin, which on average adds only 1.4 months to life expectancy for patients inflicted with advanced colorectal cancer. Sanofi priced Zaltrap at $11,000 a month, which is twice Avastin’s price. At any rate, there was resistance. Doctors at Memorial Sloan-Kettering in New York, which is one of the world’s leading cancer centers, …show more content…

The answer to this question is of course variable depending on many factors, such as drug type, material and use. However, a recent example may be used to understand the flexibility that these pharmaceutical companies truly possess. A drug called Pyrimethamine was released in 1953 by Burroughs Wellcome, a pharmaceutical company based in London. This drug was originally intended to fight malaria, after the microorganisms that cause the disease developed resistance to earlier treatments. In current times, it’s mostly used now to treat toxoplasmosis, a parasitic infection that can be life-threatening in people whose immune systems are suppressed by HIV/AIDS or cancer. In 2010, the company sold the U.S. rights to pyrimethamine (now marketed under the brand name of Daraprim) to another firm, CorePharma. By that time, the patent on the drug had long since expired, but because of the sheer difficulty, nobody bothered to make a generic, essentially making Daraprim a monopoly. CorePharma’s parent company, Impax Laboratories, then sold it to Turing Pharmaceuticals. Almost overnight, the company raised the price from $18 a pill to $750; approximately 42 times the original price. To contrast this, in Britain GlaxoSmithKline sells the drug for 66 cents a pill, and in India, it costs even …show more content…

Many of these drugs are invented not by the companies that currently sell them but by someone else. Then these companies act like big fish swallowing little fish. These larger companies either purchase many of the smaller firms outright or license promising drugs from them. These larger drug firms rarely perform research on medication other than adding slight variations to those already in their possession. These drugs with slight variations are then used to acquire new patents and maintain monopoly status over their specific markets. This means that many companies are increasing prices for their research that is used to develop these slightly-varied drugs. In essence, we are paying extra so that these companies can maintain their

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