Wilson disease is caused by a mutation in the ATP7B gene. The ATP7B gene is responsible for the metabolism of coper in our bodies. ATP7B gives instructions for making copper-transporting ATPase proteins. These proteins help with the transport of metals into and out of cells. (U.S. National Library of Medicine, 2016).
In most cases of Wilson disease the symptoms very, it all depends what body part is being affected by the high levels of copper. The liver is one of the main body parts that get affected, scarring can occur when the liver cell repair the damage that has been done due to excess copper. The more scarring the liver has the more difficult it will be to function. Since the liver is not able to push out the excess copper in the bile, it damages liver to the point that the high levels of copper get secreted in to the blood stream, the excess copper then travels to other organs (Liver Foundation, 2015).
Kayser-Flescher rings is a symptom that individuals develop that have had liver damage. Kayser-Flescher is a condition where a ring around the iris develop, the ring is a brown rust color. The color is due to the buildup of copper in the eyes. (U.S Department of Health and Human Services, 2014).
Wilson’s disease
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(U.S Department of Health and Human Services, 2014). Diet Changes are also given to patients, they must reduce the intake of mushrooms, liver, shellfish, nuts, and chocolate. (U.S Department of Health and Human Services, 2014). Liver transplant would be the last resorts for most individuals, physicians will decide if individuals would be a candidate for the transplant depending on the damage already done by the excess copper in the liver. (U.S Department of Health and Human Services,
Wilson had some important roles in World War I that took a tole on his health. Just the fact of being a president is enough pressure. What stands out most after much research is the fact of how much he wanted peace. One would not underestimate by saying he spent his life by trying to have world peace. He was a remarkable president and benefited our nation tremendously by his works.
Also evident are molluscoid pseudotumors (fleshy lesions associated with scars) frequently found over pressure points (e.g. elbows) and subcutaneous spheroids, which are commonly mobile and palpable on the forearms and shins. Complications of joint hypermobility include sprains, dislocation are common in the shoulder, patella and temporomandibular joints Muscle hypotonia and slower gross motor development also can occur It is inherited in an autosomal dominant manner (Clarke, D., Skrocki-Czerpak, K., Neumann-Potash, L.). In the Hypermobile type of EDS, the joints of the body experience Hypermobility, which is the dominant clinical manifestation. General joint hypermobility affects large (elbows, knees) and small (fingers and toes) joints. Skin is hyperextensible, smooth/velvety, and bruising occurs easily as well.
...ll understood simply because of the numerous genetic and environmental factors possible in causing any part of PDB, either by over stimulating osteoclast precursors, genetic mutations, producing transduction pathways that would otherwise not be present or even signals misfiring or over active parathyroid gland. Much more isolated research is necessary before this disease can be fully understood.
TSEs or more commonly prion diseases are a group of invariably fatal neurodegenerative diseases that occur in humans and animals . This disease is caused by a protease –resistant protein (PrPsc) after misfolding of a host-encoded prion protein (PrP). TSEs can exist as genetic, infectious or sporadic forms. The diseases are characterized by dementia, ataxia and neuropathlogically due to loss of specific neurons in the brain. Other clinical features include persistent painful stimuli, dystonia, visual or cerebellar problems and gliosis (1).
The signs and symptoms of liver injury that may be found are jaundice, abdominal pain, nausea, vomiting and asthenia. However, they are not specific enough to ascertain a liver disorder.4
Envision a life consumed by grayness and misfortune, slowly weakening the body from the inside with no proof of existence other than symptoms of a common cold. Dwindling away as skin begins to cling to bone, this monster, formally addressed as the Poliomyelitis (Polio) disease, finds its way to the nerves of the body as well as the grey areas of the spinal cord, leaving its host with dreadful affects throughout the body.Since its discovery in 1905, Polio has caused several epidemics throughout the years leaving many permanently paralyzed or even dead. Thankfully, scientists created the polio vaccination which lead to the nearly complete eradication of this disease. However, In order to ensure this disease does not spread as it once did before, people must come to understand Polio’s etiology, history and modern day epidemiology, as well as its proper response to treatment.
Prion Disease is a lethal thing that does not have a cure. Many people are dying from this and researchers are nowhere near close to finding anything to stop the disease. By making more people aware of this, it can make some that are interested in medicine and science have an drive to help find a cure. Prion Disease is a complex thing to understand completely, especially when there is no prior knowledge about this topic. So explaining the different types and other general information about the disease is important. Some more topics to discuss are cures and symptoms. Some aren’t aware that they have Prion Disease, which can lead to it spreading, and the fact that there isn’t a cure is another problem. Since Prion Disease isn’t a common topic that many hear about daily or even know about. By talking about basic information about Prion Disease and how there isn’t a cure and the symptoms that come with it, people can start to understand how important this really is because many people are dying and by informing society finding a cure with fresh eyes could be done a lot sooner.
Today there are many infectious diseases around the world. An infectious disease is defined as an infection which can be caused by the entrance, development and manipulation of microorganisms in the body. Infections are classified as emerging and re-emerging. An emerging disease is a disease that has appeared in a population for the first time, or that it may have happened previously but is rapidly increasing in incident or geographic range. Whereas a re-emerging disease is a disease that has been present at a location in the past and was considered eradicated or controlled. Some emerging and re-emerging disease present today and in the past are, HIV and Aids, Ebola, Hendra Virus as emerging diseases and Malaria, Tuberculosis, and Cholera as re-emerging diseases. In this report the re-emerging disease ‘Poliomyelitis’ will be thoroughly investigated and from reliable research, the effectiveness of the management to prevent this disease in the world will be evaluated. Poliomyelitis, often called ‘polio’ or ‘infantile paralysis’ is an infectious disease caused by a virus. This dangerous infectious disease has been eradicated around the world except for three countries, Nigeria, Pakistan and Afghanistan.
As you exit the bus, another passenger next to you starts to cough, and then you hold the handrail as you exit the bus. Since you’re late getting home, you take a shortcut through a field to get home quicker. These three simple acts just exposed you to bacteria, viruses, and insects that could cause illness or even death. Infectious diseases, also known as communicable disease, are spread by germs. Germs are living things that are found in the air, in the soil, and in water. You can be exposed to germs in many ways, including touching, eating, drinking or breathing something that contains a germ. Animal and insect bites can also spread germs.1
Tuberculosis or known as TB remains a leading cause of morbidity and mortality in the world, especially in developing countries. A combination of factors including high costs, limited resources and the poor performance of various diagnostic tests make the diagnosis of TB difficult in developing countries. According to Centers for Disease Control and Prevention (2014), one third of the world’s population is infected with tuberculosis. In 2012, nearly nine million people around the world become sick with tuberculosis disease, and there were around one point three million TB related deaths worldwide.
Hypertrichosis, which is also known as Ambras Syndrome or Werewolf Syndrome, is excess growth of hair on parts of the body. Hypertrichosis can either be generalized meaning it covers the whole body or localized meaning it is only on a certain area. There are three different hair types that may be involved. They include Lanugo (long and silky), Vellus (replace Lanugo after birth except on the scalp and eyebrows), and terminal (course, thick, and pigmented). Generalized can include all three types while acquired usually involves vellus that turn into terminal. Along with being generalized or localized, Hypertrichosis is also separated into congenital or acquired classifications. Congenital means that this disorder was present at birth and may have been caused by mutations in the genes. While acquired means that it became present over time. The cause for congenital is typically genetics while the cause for acquired is influence by medical conditions such as metabolic disorders, cancer or even oral and topical drug treatments. Congenital Hypertrichosis Lanuginosa is thought to be caused by mutations on the eighth chromosome or spontaneous gene mutations. The main sign of Hypertrichosis is excess hair growth, especially in places that hair does not typically grow in. Symptoms of Hypertrichosis may be present because of underlying conditions or chemical imbalances and the side effects of some medications. When a patient is being diagnosed with Hypertrichosis, a Doctor will determine if this was congenital or acquired. Congenital has no cure but acquired are typically triggered by factors that can be reversed or lessened so the Doctor could try to find these triggers. Hypertrichosis can cause cosmet...
Tuberculosis is an air-borne disease, hence, it can be passed from an infected person to a healthy individual through coughing, sneezing and other salivary secretions. Tuberculosis is caused by the transfer of Mycobacteriun Tuberculosis (M. Tuberculosis) also known as Tubercle Bacillus, a small particle of 1-5 microns in diameter, due to the small size, when an infected person sneezes or coughs, about 3,000 particles are expelled. M. Tuberculosis responsible for tuberculosis is able to stay in the air for a long period of time (about 6hoursAnother way of acquiring Tuberculosis is by drinking unpasteurized milk, milk straight from cow, although this is not a common mode of transmission, it can be found in rural areas. Ingestion of contaminated cow milk transmits Mycobacterium Bovis, the animal form which is still potent enough to cause tuberculosis in humans. ). Tuberculosis transmission is affected by exposure, socioeconomic status of person, proximity, immune status of uninfected individual (%&&%&? CDC).
America has been introducing foreign genes into cows, mice, sheep, and pigs for years; there is no reason that it cannot be done in humans as well (“Creating Designer Children”). Imagine parents picking their child out of a catalog instead of using God’s creation. (“Creating Designer Children”). Every child is born with the genes that are carried down the gene line of their family not by the parents picking how they want their child to be born. Genetic mutation is basically a future of designer children. Genetic mutation can cure the children of all diseases and traits that the parents do not want their child or children to have (“Creating Designer Children”). Around 1,000 to 4,000 children born in the United States will develop a disease before or around the age of 10 (“Creating Designer Children”). The question is, “will the child be born healthy or have problems later in life”? How far will parents and doctors go to engineer humans (“Creating Designer Children”)?
Tuberculosis is an infection caused by Mycobacterium Tuberculosis, an acid-fast Gram-positive bacillus, and “is characterized by progressive necrosis of the lung tissue” (Tamaro & Lewis, 2005). Tuberculosis is caused by many debilitating conditions like immunosuppression and chronic lung disease, among others. Nevertheless, human immunodeficiency virus (HIV), the virus that causes acquired immune deficiency syndrome (AIDS), remains the leading cause of tuberculosis worldwide. Tuberculosis can present in one of two types: active tuberculosis and latent tuberculosis. Prompt treatment prevents latent tuberculosis from evolving into active tuberculosis. (“Basic TB Facts,” 2012).
...ver problems. It may also make the person more likely to get infections. Blood transfusions may help control some symptoms. But this could lead to having too much iron, as it stated before. Too much iron could damage the heart, liver, and endocrine system.