Urinary Tract Infection: A Case Study

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Urinary tract infection (UTI) is a bacterial infection or inflammation of the bladder (cystitis), kidneys (pyelonephritis), or urethra (urethritis), leading to bacterial colonization of the urine. Infection of the urinary tract is a common problem, causing more than eight million office visits annually in the United States. UTI is the second most common infection that affects women. UTIs typically affect young, sexually active women. A lower UTI is an infection or inflammation of the bladder or urethra. Upper UTIs involve infections of the ureters and kidneys. Simple or uncomplicated UTIs are infections experienced by women with no significant history of UTIs and are characterized by new onset of mild to moderate symptoms. A complicated UTI …show more content…

Symptoms of acute uncomplicated UTIs are due to bladder irritation exhibiting signs of increased frequency, urgency, dysuria, and occasional hematuria. An uncomplicated UTI is a rare occurrence in the affected individual who is otherwise healthy. Usually, there are a small number of responsible pathogens vulnerable to first-line narrow-spectrum antimicrobial agents, and there are no urologic or gynecologic abnormalities. A complicated presentation including high fever, chills, flank pain, costovertebral angle tenderness, nausea, and vomiting is indicative of pyelonephritis or urosepsis (Buttaro et al., …show more content…

A clean-voided specimen reduces vaginal and labial contamination. It is advised that urine dipstick tests be used to guide treatment decisions in healthy women younger than 65 years whose UTI symptoms are mild, or presents with less than two symptoms (Shah & Goundrey-Smith, 2013). A urine dipstick provides rapid diagnostics by assessing the presence of leukocytes, nitrites, blood, protein, and/or bacteria. The presence of nitrites and leukocytes indicates bacteria in the urine, which causes urinary nitrates to breakdown into nitrites. A higher concentration of the leukocyte esterase enzyme will be present in the urine due to the increased presence of neutrophils with infection. In addition to the information obtained from the dipstick, microscopy can be used to detect hematuria, pyuria (white cells in the urine), or bacteriuria to confirm the type of bacteria and guide antibiotic selection in complicated UTI or pyelonephritis (kidney infection). A urine culture is needed for upper UTI, complicated UTI, unsuccessful treatment or reinfection of UTI (Buttaro et al.,

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