Tramadol Drug Fact Sheet

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Tramadol Drug Fact Sheet
This paper, while not intended as a comprehensive report of every fact about the analgesic drug Tramadol, will provide an in-depth review of all pertinent information.
Tramadol Description
Tramadol is a pain reliever used to treat moderate to severe pain. Classification of Tramadol falls under the opiate analgesic category (NIH 2013). To get a prescription of Tramadol you would need to be in moderate to severe-acute pain similar to that following surgery, or chronic pain as accompanies osteoarthritis (Grond & Sablotzki 2004). People should consider taking Tramadol if other drugs or alternative methods do not successfully manage their pain. The estimated cost of a prescription of Tramadol is $5.00 (NPS 2008). Tramadol is available in an immediate release (IR) formula, taken 4 – 6 times a day, or a sustained release (SR) formula taken twice daily (Grond & Sablotzki 2004).
Side Effects (See Figure 1)
Tramadol has a wide range of side effects. The following are serious and require immediate medical attention in the event that any of these symptoms appear: seizures, fever, hives, rash, blisters, difficulty swallowing or breathing, swelling of the eyes, face, throat, tongue, lips, hands, feet, ankles, or lower legs, hoarseness, hallucinations, agitation, loss of consciousness, lack of coordination, fast heartbeat (NIH 2013).
The subsequent are less serious but patients are advised to call their doctor if these symptoms persist: dizziness, weakness, sleepiness, difficulty falling asleep or staying asleep, headache, nervousness, uncontrollable shaking of a part of the body, muscle tightness, changes in mood, heartburn or indigestion, nausea, vomiting, diarrhea, constipation, loss of appetite, swe...

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...ods of action that enhance its analgesic effect.

References
Grond, S., & Sablotzki, A. (2004). Clinical Pharmacology of Tramadol. Clinical
Pharmacokinetics, 43(13), 879-923.
Häggström, Mikael. (2009). Side effects of Tramadol. [Rendered Image]. Retrieved from http://commons.wikimedia.org/wiki/File:Side_effects_of_Tramadol.svg Drugs.com. (2013, September 12). Tramadol Information from Drugs.com. Retrieved from http://www.drugs.com/pro/tramadol-capsules.html NIH-U.S. National Library of Medicine National Institutes of Health. (2013, October, 15).
Tramadol MedlinePlus Drug Information. Retrieved from http://www.nlm.nih.gov/medlineplus/druginfo/meds/a695011.html NPS-National Prescribing Service Limited. (2008 December). NPS Medicine Update Tramadol.
Retrieved from http://www.nps.org.au/__data/assets/pdf_file/0007/66346/NPS_Medicine_Update_Trama dol_final.pdf

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