Intramembranous Ossification Essay

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‘The word skeleton comes from the Greek word skeletos, meaning “dried up”. The parts of the skeletal system the bones and other structures that make up the joints of the skeleton are anything but dried up. Strong yet light, the skeletal system is made up of living material, with networks of blood vessels running throughout.’ Humans are born with approximately 300 bones and at skeletal maturity this amount will decrease to around 206 as bones eventually fuse together. The body’s bones make up the skeleton, a solid structure in which the body is built whole. Second to the teeth the bones are the hardest tissue inside the body. It gives shape, strength as well as protection for many of the vital organs enclosed within. Bones also act as storage …show more content…

Intramembranous ossification mainly occurs during the formation of the flat bones of the skull, as well as the mandible, maxilla, and clavicles. The bone is formed from connective tissue such as mesenchyme tissue rather than from cartilage. The bone is formed from connective tissue such as mesenchyme tissue. Stem cells, mesenchymal initiate the process of intramembranous ossification. A small cluster of mesenchymal cells will begin to replicate and form a group of cells called a nidus. Once the nidus is created the mesenchymal cells will no long replicate within. Certain mesenchymal cells will offset into osteoblasts, which line up around the surface of a spicule (bony matrix) and secrete osteoid increasing its size. Once trapped within the bone matrix osteoid transform into osteocyte that occupies a chamber called a lacuna. As this growth continues the spicules become trabeculae. With the continuing growth, trabeculae become interconnected and woven bone is then formed. This network of trabeculae can also be referred to as primary spongiosa. Forming around the periosteum, osteogenic cells originate which then increase the growth and a bone collar form. Eventually the woven bone is replaced by lamellar bone. Intramembranous ossification is also an essential process for healing of bone as

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