Schizophrenia Genes and Environmental Basis

[1]Schizophrenia is a chronic and severe brain disorder, though most people may call it an illness. With this disorder the person is more likely to experience “Imaginary friends”,[2] Hearing voices that are not there, and being very paranoid. The people who have schizophrenia are often withdrawn and can be agitated easily. [3]The main thought to the symptoms are known to be paranoia, although the symptoms can vary depending on the person and what type of schizophrenia that he or she may have. [6][7]There are five types of schizophrenia, which include, paranoid, disorganized, catatonic, undifferentiated, and residual schizophrenia.

[3]The disorder is thought to be environmental. Trauma, emotional, and stress disorders are mentioned as people who have had difficulties with schizophrenia would have no record of the genetic based disorder in their family.

[5]Most people do not find out that they have schizophrenia until late childhood. It is rare for children to find out before the age of ten. While others may not find out until they are in their late thirties or early forties. The symptoms can be developed over time. Females seem to receive the symptoms later than males do.

[3]Schizophrenia affects about 1% of the population. Schizophrenia affects men about 1½ more times than women.

Schizophrenia is found to be more likely in relatives of a schizophrenia person. People with an aunt, uncle, cousin, or grandparent with the disorder are found most likely to get it more so than any other bystander. Someone with a parent or sibling that has the disorder has a 10% chance of getting schizophrenia. The most likely to have this disorder is an identical twin. The identical twins, twin (brother or sister) has a 40-65% chance of giving ...

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... starts relaxing the supercoils and altering of DNA and interacts with DNA helicase SGS1 and plays a role in DNA recombination, also cellular aging and maintenance of genome stability. Alternate splicing results in multiple transcript variants. Additional spliced variants of the gene have been described, but their complete length is unknown.

Schizophrenia is fundamentally based on genes, though there are environmental factors. The environmental factors are not completely proven in all people with schizophrenia. The main factors are the genes that are not specified because of the uncommon mutation, which can not yet be completely known by scientists. Now the genetic mutation TOP3B is known as a gene associated with schizophrenia, but scientists will keep trying to inquire more genes such as this one for more unique mutations seen in many people with schizophrenia.