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Drug discovery and clinical research
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Research Proposal: Are antidepressants as effective as the pharmaceutical companies claim?
Introduction: For my research project I would like to explore the effectiveness of antidepressant drugs. Antidepressant drugs are used are used to treat major depression and other conditions, some of which include anxiety, obsessive compulsive disorder, chronic pain and other disorders. Around the world antidepressants are used to cure these types of mental illnesses. It is argued by both medical professionals and other people whether or not they believe that antidepressants work. According to Mayo Clinic one in ten Americans take an antidepressant. Today, antidepressants have became the most common way around the world to treat major depression
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To support my argument, I will need to inform my readers about the positive effects of antidepressants and then discuss governments role and how they can benefit from antidepressant drugs. My audience are my classmates (from many different backgrounds and studying different majors) and my professors. Although there is a wide range of articles and research on this topic, I believe the general public is not fully aware on the positive effects of antidepressants. My goal is that after reading my paper, the person will have a better understanding on the effectiveness of antidepressant drugs. I will be creating a research paper to explain my research and arguments to my audience. The printed copy of my paper will allow my readers to read my findings at their own pace and it will provide them with the easiest way to find the sources that I used to conduct further …show more content…
I have also came across in publications including WebMD, mention the uses of antidepressants. On the other hand I have found other articles that contradict the effectiveness of antidepressant drugs. I have also information on from the Mayo Clinic that talks about different antidepressants and which ones work better for different mental illnesses.
Search Plan and Relevant Sources: I will need to continue to seek out of range perspective on antidepressants as I develop my own argument. I plan to conduct some field research by interviewing people that have used antidepressant drugs. My friend, who would prefer to keep her identity private, has suffered from depression and has used antidepressants to treat her mental illness has a agreed to an interview. I also plan to do some further research and see if a doctor who prescribes antidepressants if they would be willing to set up an
This paper will have two sections: The first section will be a brief explanation on what is depression. In addition, what is the percentage of depress people in the United States. Furthermore, it will discuss in details several theories that are best suited to treat depression disorder. Moreover, the theories that will be briefly discussed are as follows: Cognitive Therapy (CT), Cognitive Behavioral Therapy (CBT), and Interpersonal Therapy (IPT). The second section will be a summary of a counseling session the learner had with a client and the treatment that was given to help alleviate and ceased the depression from reoccurring.
Treating depressive and bipolar disorders with antidepressants remains a popular option in clinical practice. Most clinicians choose the drug or class of drugs, usually selective serotonin reuptake inhibitors, SSRI's, that is most effective and best tolerated with fewer severe side effects. These drugs are beneficial because they specifically target serotonin-based areas of the brain without affecting other neurotransmitter systems. SSRI's largely replaced tricyclic antidepressants which work by blocking the absorption (reuptake) of the neurotransmitters serotonin and norepinephrine, thereby increasing the levels of these two neurotransmitters in the brain. Tricyclic antidepressants present severe side effects and thus are usually only used when other treatments have failed. If SSRI's or tricyclics are not effective Monoamine oxidase inhibitors may be prescribed. MAOI's, enhance tyramine to increase norepinephrine and serotonin. While taking MAOI's you must abstain from foods and alcohol that contain tyramine such as, yogurt, aged cheese, and substances such as cold medications. This is because a potential toxic reaction could occur. Additionally, other antidepressants may be utilized such as Wellbutrin (bupropion) an NDRI-
Antidepressants are FDA approved drugs given to patients to alleviate symptoms, most commonly anxiety and depression. There are many people who are skeptical about the use of these drugs and if they really work as a benefit toward the people taking them. There are many pros to taking the medications, but there are also cons. This is why users of these drugs have to be aware of the side effects in order to get the full use of the medicine. Research shows that the benefits of antidepressants outweigh the negative long term effects, but only if they are taken in moderation.
... the body feels as the result of any number of reasons. Spreading more information to the public to raise awareness of the detrimental effects of antidepressants is the only way to combat the ongoing problem.
What determines a good' article from a bad' one? In the Des Moines Register on February 3, there was an article titled, More parents, doctors refuse to put kids on antidepressants," was written by Marilyn Elias. Elias is a well-known writer from USA Today, and has written on topics such as stress, marriage, and health. The article was about the effects on children, ages 18 and younger, taking depression pills. There are many elements that establish a good' article from a bad' one. Some of these elements would be the content, reader, and credibility.
“Suicide is the third leading cause of death for 15- to 19-year-olds. In any given year, about 20% of all high school students think of committing suicide; almost 10% try” (Cropper 112). This shocking statistic shows the high risk of suicide among teens, but what some might not know is that the most common form of treatment used to help teens suffering with depression is one that might also increase the risk of suicide and/or harmful actions to oneself. Tricyclic antidepressants such as Zoloft, Paxil, Celexa, and Lexapro are commonly prescribed to adolescents and young adults to relieve symptoms of depression, and they work by either releasing more of the brain’s “happy chemical,” serotonin, in those with clinical depression, or by stopping the release of the brain’s emotional chemicals in those with manic depression (or other diseases such as bipolar disorder) (Silverstein 61). Although antidepressants can have a positive effect on the symptoms of depression, the risk of suicide among those who take it is too high to use as a first option. Suicidal behavior is a serious side effect in teens that are prescribed tricyclic antidepressants; depression should be treated with safer alternatives, such as behavioral treatment or other forms of therapy as opposed to such a “trial and error” approach.
According to the FDA, about 2.5% of children and around 8% of adolescents are affected by depression (Temple). A common way to treat depression is by taking antidepressants. Children and teens have also been prescribed antidepressants for various reasons other than depression such as OCD and anxiety disorders. While it is legal for teenagers and children to take antidepressants, many people are concerned with the issues that taking antidepressants have. Children and teens should be allowed to take antidepressants only when other forms of therapy don’t work. Antidepressants are serious drugs that have severe warnings when children and teens use them. There is also an increased risk of worsening depression and suicide in children and teens, especially in the when they begin to take it. Even the less severe side effects can make quite a negative impact on life.
Antidepressants are a prescription drug now used by people of all ages. They have become a part of society, therefore, taking antidepressants is not frowned upon. Antidepressants are used to make people feel “happier” and not to feel sadness. This is shown in the dystopian society in the book Brave New World written by Aldous Huxley in 1932. In that society the people use soma, a well-known drug, to make them feel no pain and are conditioned to think soma fixes everything. Helmholtz and Bernard two main characters, do not take it because they want to be able to see the world for what it is. They also do not want soma to change how they feel; they want to appreciate nature. In addition Lenina and Henry love taking soma because then they cannot feel any pain, they are just happy all the time. In our society, people think that antidepressants will make them feel no pain and that these medications will fix all of their problems. Antidepressants have a negative impact on society today as well as in the book Brave New World.
...ceutical productions which define the pathology itself. In support of the idea that depression expresses a reduced capacity to interact with the environment rather than an abnormality based around an unidentifiable measurement of “chemical balance,” I will argue that the way in which pharmaceutical drugs standardize chemical deviance and treat mental illness like a biological disease disregards the normative component of depressive illnesses which must be considered as a response in one way or another to the environment in which they are experienced by each patient. By thinking about antidepressants not as correctional of a biological pathology but as a form of adaptation, I hope to show how their use must be considered in relation to values which combine scientific, social and experiential components that cannot be explained by scientific means alone.
Antidepressant are a form of pharmacotherapy treatment developed to treat the symptoms of major depression. Antidepressants are used for many other types of conditions including anxiety disorders, obsessive compulsive disorder, dysthymia, eating disorders, sleeping disorders, and substance abuse, pain syndromes, gastrointestional disorders. Antidepressants usually require several weeks to notice significant effects. There are no antidepressants or any medication that is completely free of adverse effects. This article explains that the adverse effects of antidepressant can decrease compliance and slow down the rate of recovery. It is important for one to take note of potential side-effects before choosing the best antidepressant to suit their personalized needs. Statistics show that about 28 percent of patients sto...
I am quite fascinated by generalized control mechanisms and the role they play in the nervous system. I am also quite curious about the relationship between different generalized control mechanisms. The concept of mood and depression in particular have always interested me. I have always wondered what actually causes depression. Why can some people be in a perfectly good mood one day and then less than a week later start exhibiting the signs of clinical depression? I have always been curious about the role that experience and chemical imbalances play in depression and other mood disorders. I donUt totally understand how chemical depression can originate as the result of severe outside stressors in a personUs life. How can this stress go from simply stress in the experiences and environment of a person to a chemical imbalance? I have also wondered why certain people are more susceptible to depression than others. I am curious about whether genetics play a role in depression and whether certain people are more susceptible to depression because of the environment they live in or because of pharmacological reasons and genes. Throughout our class this year, I have wondered about the role that the I-function plays in depression. I find it interesting that it is possible to wake up one morning and be in a nasty mood even if I want to be in a good mood and my I-function is thinking RhappyS thoughts. Through my research for this paper I wanted to find out more about the different kinds of depression and exactly what goes on chemically in the brain when a person is depressed. I also wanted to do a little research on how depression can be treated. I wanted to try and determine how and when the line of simp...
Starting college can be a stressful time for any adolescent. For students suffering from depression it can be a traumatic experience. Worlds feel turned upside down. Even for those who manage to “cope,” pressures can cause these students to feel overwhelmed.
Nemeroff, Charles B., et. el. (2003) Differential Responses to Psychotherapy versus pharmacotherapy in Patients with Chronic Forms of Major Depression. National Academy of Sciences, v100, i24, pg.142(4)
Depression is a mental illness, which affects millions of Americans each year. Currently there are many prescription drugs, called anti-depressants that have been proven to successfully treat it. The causes of depression are somewhat of a medical enigma, however, it is known that depression is associated with a change in the brains chemistry involving the function of neurotransmitters (Reichert). This chemical change occurs in healthy brain’s, which experience sadness, but ends after the unpleasant stimulus is removed. In people suffering from depression this chemical change does not correspond to any particular stimulus. Symptoms of depression are often incapacitating and include severe and extended sadness, feelings of worthlessness, feelings of emptiness, irritability and anxiety (Reichert, Spake).
Treatment for depression includes medicine, psychotherapy, and electroconvulsive therapy. If someone is thinking about suicide or is very depressed and cannot function, they need to be admitted into a hospital. Antidepressants are medicines used to treat depression. They help bring the chemicals in the brain to the normal level and relieve syndromes. If the patient feels as though the medication isn’t working, their doctor should be called. However, if you feel so, you shouldn’t change them on your own without the permission of the doctor. Psychotherapy is to help you understand why you’re feeling the way you are.