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An essay on osteosarcoma
An essay on osteosarcoma
An essay on osteosarcoma
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TOPIC: Osteosarcoma
SPECIFIC PURPOSE: To inform my audience on what osteosarcoma is, how it is treated, and Zach Sobiech’s story.
THESIS STATEMENT: Osteosarcoma is a rare type of cancer that weakens the bone.
INTRODUCTION
I. The human body consists of 206 bones and osteosarcoma can develop in any one of them; do the math, that’s 206 possible places for osteosarcoma to occur. (Attention getter)
II. We all came into this classroom by walking; in order to do so we not only need functioning legs, but functioning bones as well.
III. Osteosarcoma is both rare, and extremely hard to treat because none of its treatments guarantee a cure. (Thesis)
IV. Today, I’ll talk to you about osteosarcoma, what it is, how it is treated, and I will tell you Zach Sobiech’s story. (Preview)
Transition: So, what exactly is osteosarcoma?
BODY
I. Osteosarcoma is simply a rare type of cancer that develops in the bone.
A. It is most common in long bones, especially those around the knee.
1. Other sites for osteosarcoma according to www.hopkinsmedicine.org include the upper leg, or thighbone, the lower leg, upper arm bone, or any bone in the body, including those in the pelvis, shoulder, and skull.
2. In the following visual, Hannah Thompson (Bone Cancer Research Trust, www.bcrt.org.uk) provides us with an image *shows the image* stating that:
a. 94% of all osteosarcomas develop in the bones of the arms and legs.
b. 15% of which occurs in the upper arm bone, or humerus.
c. 48% of which occurs in the upper leg bone, or femur.
d. 4% of which occurs in the back lower leg bone, or fibular.
e. 27% of which occurs in the front lower leg bone, or tibia.
f. She also states that the remaining 6% occur in areas such as the skull, ribs, pelvis, lower arm, hand,...
... middle of paper ...
...r runs out, and instead it finds sweeter places and extracts the flavor out of them without remorse. (Memorable close)
Sources:
What are the risk factors of osteosarcoma? From http://www.cancer.org/cancer/osteosarcoma/detailedguide/osteosarcoma-risk-factors
Treatments of osteosarcoma: http://www.macmillan.org.uk/Cancerinformation/Cancertypes/Bone/Typesofbonecancer/Osteosarcoma.aspx#
Osteosarcoma: http://annonc.oxfordjournals.org/content/21/suppl_7/vii320.full
Zach Sobiech’s story: http://www.childrenscancer.org/zach/
The Osteosarcoma Research’s View: http://www.dana-farber.org/Newsroom/Publications/The-Osteosarcoma-Researcher-s-View.aspx
What is Osteosarcoma? From: http://www.dana-farber.org/Newsroom/Publications/The-Osteosarcoma-Researcher-s-View.aspx
Osteosarcoma: http://www.hopkinsmedicine.org/healthlibrary/conditions/adult/bone_disorders/osteosarcoma_85,P00127/
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Osteosarcoma is a malignant cancer of the bone. This tends to be in the extremities of the human body. It tends to occur in the shin, thigh, and upper arm, usually large bones with very fast growth rates. But it can occur in any bone. This type of cancer is most common in teenagers and people over 60. ("Osteosarcoma") In teens with cancer, about 5% is osteosarcoma. ("Osteosarcoma" Teens Living with Cancer.) It is more common in males than females. (“Disease Information”) In males it usually affects people between the ages of 15-19. And in girls, it is usually ages 10-14. Most teens effected are taller compared to the average. ("Osteosarcoma" Teens Living with Cancer.) Growth spurts can onset this cancer so it is very rare in children less than 5 years of age. (“Disease Information”) It usually is never expressed in children before puberty. ("Osteosarcoma" Teens Living with Cancer.) There are more incidences of this in black children than in white children. (“Disease Information”) This could be as a result of the genetic factors. This ...
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Despite ongoing research, the cause of osteosarcoma is still unknown. Occurring in 2 persons per million per year (Michael et al., 2006) osteosarcoma is the most common primary tumor of the bone, but yet its incidence amongst malignant tumors is rare. However there are numerous factors that have been shown to effect prevalence. Osteosarcoma occurs predominantly in males, although the tumor does have a tendency to develop earlier in females (American Cancer Society, 2014). The risk of osteosarcoma is highest for people who are aged between 10 and 30. Most common however is during the teenage growth spurt, due to the rapid bone growth and higher chance of a mutation occurring in DNA replication. Height can also be a risk factor. Children with osteosarcoma are generally tall for their age, which again indicates a link to rapid bone growth. Osteosarcoma also appears to have a slightly higher prevalence in African Americans than other races. There is also evidence of genetic predisposition being a risk...
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