Laminitis Essay

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The majority of clinical cases of laminitis occur at pasture where there is an accumulation of rapidly fermentable non-structural carbohydrates (NSC) such as fructans, simple sugars or starches (Geor, 2010). Pasture-associated laminitis has major economic and welfare implications in the equine sector. Increased risk factors include insulin resistance, increased insulin secretory response, hypertriglyceridaemia and obesity (Asplin, et al., 2007;Carter, et al., 2009 and de Laat, et al., 2010). Insulin resistance has been associated with a number of problems in the horse, most notably laminitis. Insulin resistance can be defined as a physiological condition in which cells have a diminished response to normal actions of the hormone insulin. Insulin is produced but the cells become resistant and are less capable in transporting glucose from the bloodstream to muscle and other tissues. In horses, insulin resistance is associated with a number of diseases such as Equine Metabolic Syndrome (Powell, et al., 2002; Hoffman, et al., 2003;Vick, et al., 2006 and Frank, et al., 2009), Equine Cushing Disease (McGowan, et al., 2004 and Walsh, et al., 2009) and Laminitis (Treiber, et al., 2006;Bailey, et al., 2007;McGowan, 2008 and Geor, 2008). Obesity and insulin resistance in ponies has become a common problem and there is a growing awareness on the role that diet and exercise has to play (Jeffcott, et al., 1986; Frank, et al., 2006 and Vick & Adams, 2007). Over-expressed adipocytokines, such as leptin, have been suggested to impair insulin signalling and cause the up regulation of inflammatory cytokines. This then further contributes to impaired insulin signalling and endothelial dysfunction (Radin, et al., 2009). The restriction of energy throu...

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...s limited supply to minimise stress. Horses should be kept off the first new shoots after a period of stress such as drought. The NSC concentration can be reduced by waiting until the new grass has two the three leaves per tiller. This allows the sugars that have gathered in the underground storage organs to be utilised for production.

6. Conclusion
A number of factors can affect the NSC content including the type of plant (grass hays, legume hays, oat hay) maturity of plant (young plants tend to be higher), the environmental conditions (stressed grasses have higher amounts of NSC), the season (spring has largest content of NSC) and time of day (afternoon). The factors mentioned above as well as the curing process will affect the NSC content of forage. The longer hay has being dried the lower the NSC, soaking hay can also remove a large amount of the NSC content.

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