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1st polio research document
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Short essay on history of vaccines
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The Knowledge of Plague dates back to Columbus's discovery of America, where Europeans spread deadly diseases such as Smallpox, measles, and influenza to Native Americans. Throughout history countless epidemics took the lives of mankind. Humanity tackled on these diseases with the development of vaccinations. Vaccines have vastly been improved through the growth of human civilization. Life before vaccines was devastating and took extreme measures. A form of treatment for smallpox is known as inoculation or variolation, where dried smallpox scabs were blown into the nostrils of an individual who then would get a mild form of the disease. Once that individual recovered they would be immune to smallpox. According to the U.S. National Library of Medicine (NLM) variolation was not risk free, not only could a patient die from the procedure but the mild form of the disease could spread causing an epidemic. …show more content…
The Iron lung was invented to help polio patients breath due to the disease paralyzing muscle groups leaving patients unable to breath on their own according to the Smithsonian National Museum of American History. Children who encountered polio would spend weeks or months inside the iron lung, polio was one of the most feared diseases. The Center for disease control and prevention states polio crippled an average of more than 35,000 people in the united states each year. As polio vaccines began to arise the iron lung was left in the past in comparison with variolation. Dr. Jonas Salk created the Salk vaccine using a killed version of the virus in 1955. The vaccine was proven to be effective based on the Salk Institute for biological studies two years before the vaccine was available the number of polio cases in the U.S. was 45,000 by 1962 the number dropped to
Plagues and Peoples written by William H. McNeill follows the patterns of epidemics and endemics within human history. It is within this history that McNeill finds parallels between diseases and humans in the forms of microparasitism and macroparasitism. Merely from the title, McNeill gives equal importance to viruses and humankind. In several instances, humans behave the same way viruses, bacteria, and parasites do in order to survive and to compete. Surprisingly enough, McNeill’s overarching theme can be summarized using his last sentence, asserting that “Infectious disease which antedated the emergence of humankind will last as long as humanity itself, and will surely remain, as it has been hitherto, one of the fundamental parameters and
Roos, Anna Marie E. "Plague, Early History." Infectious Diseases: In Context. Ed. Brenda Wilmoth Lerner and K. Lee Lerner. Vol. 2. Detroit: Gale, 2008. 627-634. In Context Series. Gale Virtual Reference Library. Web. 17 Mar. 2014.
In closing, the variola virus affected a great amount in that era including, military strategy, trade, and native populations. Elizabeth A. Fenn’s book Pox Americana: The Great Smallpox Epidemic of 1775-82 sheds light on a significant aspect of that era that had not been given proper credence beforehand. She also illuminated the effect of smallpox when it came to race and social status. With regard to race, smallpox decimated much of the non European populations partly because of their lack of an innate immunity to that virus and Europeans lack of regard for those of a different race. Fenn’s argument on social status showed how the poorer strata’s of society suffered more severely from the variola virus because of their lack of finances to get inoculated; thus, the poor often suffered a worse strain of the virus which often lead to death.
William H. McNeill makes a monumental contribution to the knowledge of humanity in his book Plagues and Peoples. He looks at the history of the world from an ecological point of view. From this viewpoint the history of human civilization is greatly impacted by changing patterns of epidemic infection. Plagues and Peoples suggests that "the time scale of world history...should [be] viewed [through] the "domestication" of epidemic disease that occurred between 1300 and 1700" (page 232). "Domestication" is perceived "as a fundamental breakthrough, directly resulting from the two great transportation revolutions of that age - one by land, initiated by the Mongols, and one by sea, initiated by Europeans" (page 232). This book illustrates how man's environment and its resident diseases have controlled human migration, as well as societal successes and failures. McNeill discusses the political, demographical, and psychological effects of disease on the human race. He informs his audience that epidemics are still a viable threat to society, and warns of potential future consequences.
Diseases like the Bubonic Plague can be very deadly and hurt the society. The Bubonic Plague was a very devastating disease in the mid 1300s. It lasted about 6 or 7 years, and killed nearly 50% of the European population.The disease was believed to have started in China and went down the European trade route. Also one theory is that enemy’s would catapult infected carcasses into other enemies villages. And people in the villages didn’t have anything to stop the disease from spreading so it would wipe out entire villages.(document 1)
All of Camus' writings may be viewed as a quest for meaningful values in a world of spiritual aridity and emptiness. He begins with man's despair, estrangement, fear, suffering and hopelessness in a world where is neither God nor the promise that He will come- the fundamental absurdity of existence- but ultimately affirms the power of man to achieve spiritual regeneration and the measure of salvation possible in an absurd universe. This radical repudiation of despair and nihilism is closely bound up with his concept of an artist. Camus conceives of art as a way of embracing a consciousness of the absurdity of man's existential plight. But art becomes a means of negating that absurdity because the artist reconstructs the reality, endowing it with unity, endurance and perfection. By taking elements from reality that confirms the absurd existence, an artist attempts to correct the world by words and redistribution. Thus the artist never provides a radical transformation of reality but a fundamental reinterpretation of what already exists. He provides a new angle of vision of perceiving reality. That is why, for Camus, an artist is a recreator of myth. He teaches humanity that contemporary man must abandon the old myths that have become otiose, though once defined his existence. The artist liberates man to live in his world by redefining both man and the condition in which he exists. In this regard, it is important to point out that, for Camus, the traditional opposition between art and philosophy is arbitrary. It is because they together become most effective to create the redefinition: the philosophy awakens the consciousness and the art, propelled by such a radical discovery, ...
The Plague (French, La Peste) is a novel written by Albert Camus that is about an epidemic of bubonic plague. The Plague is set in a small Mediterranean town in North Africa called Oran. Dr. Bernard Rieux, one of the main characters, describes it as an ugly town. Oran’s inhabitants are boring people who appear to live, for the most part, habitual lives. The main focus of the town is money. “…everyone is bored, and devotes himself to cultivating habits. Our citizens work hard, but solely with the object of getting rich. Their chief interest is in commerce, and their chief aim in life is, as they call it, 'doing business’” (Camus 4). The citizens’ unawareness of life’s riches and pleasures show their susceptibility to the oncoming plague. They don’t bother themselves with matters not involving money. It is very easy for the reader to realize that they are too naive to combat the forthcoming calamity. The theme of not knowing life is more than work and habits will narrow the people’s chances of survival. Rieux explains that the town had a view of death as something that happens every day. He then explains that the town really doesn’t face towards the Mediterranean Sea. Actually it is almost impossible to see the sea from town. Oran is a town which seems to turn its back on life and freedom. The Plague was first published in 1948 in France. “Early readers were quick to note that it was in part an allegory of the German occupation of France from 1940 to 1944, which cut France off from the outside world; just as in the novel the town of Oran must close its gates to isolate the plague” (“The Plague” 202). When the plague first arrives, the residents are slow to realize the extreme danger they are in. Once they finally become aware of it...
In his novel The Plague, Albert Camus presents a pseudo-historical documentary of a plague that confines and controls the citizens of Oran within their city gates. The plague possesses the power of life and death over the people, as it determines which citizens will face their death or those who work to stop death. These latter men, personified by the characters of Rieux, Grand, and Tarrau, each struggle endlessly to master the plague's power over their lives, even with the realization they may never succeed. For Camus, this idea of an "impossible struggle" against an unseen power resonates throughout the novel and reoccurs in another "plague" which these men must contend with - the limits of human language. Camus's characters place great emphasis and importance upon the power of language and lament their inability to express themselves clearly.
From 166 A.D. to 180 A.D., The Antonine Plague spread around Europe devastating many countries. This epidemic killed thousands per day and is also known as the modern-day name Smallpox. It is known as one of deadliest plagues around the world.
As people tried to make sense of the Plague, they reacted extremely and made irrational decisions, such as laying blame on outsiders or on themselves, like the flagellants did. One of the immediate extreme reactions to the Plague was hedonism which was when people “lived for the moment” so they would indulge in sexual and alcoholic orgies. Another immediate reaction was flight of the wealthy and powerful to their country estates.An important group arose during the Plague called the flagellants, they believed that the Plague was sent by god for the sins they had committed. The flagellants tried to gain forgiveness from God by hurting themselves. They would usually march in groups of 200 to 300 people but occasionally the groups would become as large
The first recorded smallpox outbreak occurred in 1350 BC during the Egyptian-Hittite war. The illness was passed from Egyptian prisoners to the Hittite population affecting both soldiers and civilians. Although it wasn’t until the late 1600’s that people in Europe and Asia accidentally discovered that those infected with smallpox through a scratch on the skin, suffered from a less severe form of the disease than those who contracted it through the respiratory tract. In the early 1700’s doctors began to store samples of smallpox pus and scabs in jars. If an outbreak occurred the doctor would make a small cut in a person’s arm and smeared the pus into the wound. This process of intentionally infecting a person with the smallpox virus in order to make them immune to the disease in the future was called inoculation.
Vaccines are one of modern medicine 's game-changing breakthroughs, but they have been around for hundreds of years earlier in primitive forms. Dating back to medieval times, the first precursor to modern vaccination occurred in China around the tenth century. (2) Known as variolation or inoculation, the method was used to prevent smallpox that plagued Europe and Asia. (2) Chinese doctors found that when healthy people were exposed to smallpox scab tissue, they were less likely to get infected or got a milder, less dangerous case. (2) The most common form of inoculation in China was to crush smallpox scabs into powder and then breathe it through the nose.(2) Because smallpox was such a destructive disease, in the late 1700 's, George Washington ordered mandatory inoculation for troops who hadn 't survived smallpox before. (2) Also in the late 1700 's, Edward Jenner
After there was an outbreak of smallpox in 1000CE, the smallpox immunization was created to limit the fatalities. Eventually, the inoculation traveled to Africa, Europe, and the Americas. However, in 1796, Edward Jenner used cowpox components to create an even stronger immunity. Over the next two centuries, that method undertook several medical changes. Furthermore, in the 1930s, vaccines against many diseases such as tuberculosis and typhoid developed. More recently however, vaccine research and development led to a vaccine for polio ("All Timelines Overview," n.d.). When creating a vaccine, the goal is to weaken the virus in order for the person suffering to develop immunity to it. When the vaccine is inserted into the body, it is programed to create Memory-B Cells, which protect against additional infection (Offit, 2013). The chemicals often found in a vaccine include a suspending fluid such as sterile water, a preservative, and an enhancer that helps advance the vaccine's efficiency. A vaccine also contains a weakened part of the infection cell. When the person receives the vaccine, the body reacts by creating antibodies. In other words, the injections expose people to germs, so that their body can learn to be immune to the disease (Great Ormond Street Hospital, 2013).
Medicine in the middle ages started with the Bubonic plague also known as the Black Death. The Black Death appeared in the Mediterranean region around 542 A.D., and the Black Death was an epidemic with high mortality and killed millions of people. The plague reached and invaded Europe in 1347 A.D. affecting Italy first, then France, England, and finally northern Europe. The Black Death killed rich and poor people. The cause of the epidemic plague was by bacteria Yersinia Pestis according to the researchers on the skeletons of plague victims by testing their DNA and proteins, but there are many other pathogens wich means that any organisms that cause disease-like virus, bacteria, fungus, and parasites. In this era, there is no identified for
When thousands of rats begin dying and rotting in the streets of Oran, the citizens are bewildered. It is when the peculiar cases of a severe fever begin appearing that Dr. Rieux and Dr. Castel dare to consider that the plague has descended upon the city. For this reason, The Plague by Albert Camus is appropriately named. The novel explores the condition of a society living in constant fear of a disease that almost guarantees death. The title does not only reflect the name of the disease but as well as the event of the plague. The book is a chronicle of the events and the conditions, that urge the reader to hold on to the past.