HIV Case Study
1. What is PJP?
PJP is known as Pneumocytis jiroveci and is a fungus that infects the lungs. This fungus mainly infects those with an unsubstantial immune system, in this case, HIV is the cause of a weakened immune system that allowed Pneumocytis jiroveci to infect the lungs. PJP is found in the environment and was very rare before the AIDS epidemic. The common symptoms of PJP are fever, fast breathing pattern, trouble breathing with activity, and a dry cough. PJP can be life threatening if allowed to lead to respiratory failure and progress to death, however early treatment is often effective with corticosteroids and anti-infection medications. https://medlineplus.gov/ency/article/000671.htm
2. What is the significance of the purplish spots over K.D.’s neck and arms?
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The patient needs a skin biopsy of these spots for diagnosis. When Kaposi’s Sarcoma is diagnosed in a patient with HIV this leads to a further diagnosis of AIDS due to the nature of the cancer. http://www.aidsmap.com/Symptoms/page/1254975/#item1255277
3. Differentiate between HIV positive status and AIDS.
HIV is the virus and AIDS is the condition. AIDS is a disease that is caused by HIV, however a person can have HIV without having AIDS. HIV is a virus that works against the immune system and some people with HIV will progress through the disease and develop AIDS.
It is a virus that gradually attacks the immune system, which is our body 's natural defence against illness. If a person becomes infected with HIV, they will find it harder to fight off infections and diseases. AIDS stands for acquired immune deficiency syndrome. AIDS is a syndrome caused by the HIV virus. It is when a person’s immune system is too weak to fight off infections, and develops when the HIV infection is very advanced.
Eighteen patients were consequently infected by KPC in the hospital and six died of it.
Hospital-acquired infections (HAI) are preventable and pose a threat to hospitals and patients; increasing the cost, nominally and physically, for both. Pneumonia makes up approximately 15% of all HAI and is the leading cause of nosocomial deaths. Pneumonia is most frequently caused by bacterial microorganisms reaching the lungs by way of aspiration, inhalation or the hematogenous spread of a primary infection. There are two categories of Hospital-Acquired Pneumonia (HAP); Health-Care Associated Pneumonia (HCAP) and Ventilator-associated pneumonia (VAP).
Mrs. Jones, An elderly woman, presented severely short of breath. She required two rest periods in order to ambulate across the room, but refused the use of a wheel chair. She was alert and oriented, but was unable to speak in full sentences. Her skin was pale and dry. Her vital signs were as follows: Temperature 97.3°F, pulse 83, respirations 27, blood pressure 142/86, O2 saturation was 84% on room air. Auscultation of the lungs revealed crackles in the lower lobes and expiratory wheezing. Use of accessory muscles was present. She was put on 2 liters of oxygen via nasal canal. With the oxygen, her O2 saturation increased to 90%. With exertion her O2 saturation dropped to the 80's. Mrs. Jones began coughing and she produced large amounts of milky sputum.
My disease is Streptococcal pneumonia or pneumonia is caused by the pathogen Streptococcus pneumoniae. Streptococcus pneumoniae is present in human’s normal flora, which normally doesn’t cause any problems or diseases. Sometimes though when the numbers get too low it can cause diseases or upper respiratory tract problems or infections (Todar, 2008-2012). Pneumonia caused by this pathogen has four stages. The first one is where the lungs fill with fluid. The second stage causes neutrophils and red blood cells to come to the area which are attracted by the pathogen. The third stage has the neutrophils stuffed into the alveoli in the lungs causing little bacteria to be left over. The fourth stage of this disease the remaining residue in the lungs are take out by the macrophages. Aside from these steps pneumonia follows, if the disease should persist further, it can get into the blood causing a systemic reaction resulting in the whole body being affected (Ballough). Some signs and symptoms of this disease are, “fever, malaise, cough, pleuritic chest pain, purulent or blood-tinged sputum” (Henry, 2013). Streptococcal pneumonia is spread through person-to-person contact through aerosol droplets affecting the respiratory tract causing it to get into the human body (Henry, 2013).
This more severe form usually prevails in elderly, cigarette smokers, people with chronic lung disease, or those who are immunocompromised, such as cancer or AIDS patients. Virulence:.. Being a gram-negative bacterium, L. pneumophila has lipopolysaccharides (LPS) that act as endotoxin within a human host. The presence of a flagella is thought to mediate adherence to human lung cells, thereby causing infection, since flagella-less strains do not cause disease. Once attached to human cells, the organism is engulfed by a macrophage that utilizes the internal environment to multiply.
Acquired Immune Deficiency Syndrome (AIDS), specific group of diseases or conditions that result from suppression of the immune system, related to infection with the human immunodeficiency virus (HIV). A person infected with HIV gradually loses immune function along with certain immune cells called CD4 T-lymphocytes or CD4 T-cells, causing the infected person to become vulnerable to pneumonia, fungus infections, and other common ailments. With the loss of immune function, a clinical syndrome (a group of various illnesses that together characterize a disease) develops over time and eventually results in death due to opportunistic infections (infections by organisms that do not normally cause disease except in people whose immune systems have been greatly weakened) or cancers.
HIV, also known as Human Immunodeficiency Virus, is a virus that attacks the body’s immune system. If left untreated, HIV reduces the number of CD4 cells in the body, which makes a person more likely to get infections or infection-related cancers. HIV can also lead to AIDS (acquired immunodeficiency syndrome), if it is not being treated (aids.gov). There is no effective cure for HIV, however with proper treatment and medical care, HIV can be controlled. In
It will be difficult for a HIV/AIDS patient to keep away from all of these different types of infections but constantly taking their antiretroviral medication is the first step. Routine physicals, blood tests, and eye examinations are significant because at times the patient may have no symptoms.
In patients infected with K. pneumonia, inflammatory mechanisms can cause tissue damage that is related with a release of “alarm proteins” (Achouiti, 2012). These alarm proteins are known as the Damage Associated Molecular Patters (DAMPs) and are seen in neutrophils where they potentially affect up to 45 percent of the cytoplasmic protein (Achouiti, 2012). This is harmful because it inhibits the body’s ability to fight the infection, as neutrophils are the body’s natural immunity defense.
Acquired Immunodeficiency Syndrome or AIDS is cause by Human Immunodeficiency Virus (HIV) of genus lentivirus which is one part of the retroviridae family. There are two types of HIV which had been identified, HIV-1 and HIV-2. Shape and structure of HIV is roughly spherical with diameter of 1/100000 of a millimeter. HIV had a viral envelope which coats the external surface of the virus.
Human Immunodeficiency Virus (HIV) is a virus that your body can’t get rid of. This virus sits in your body and attack your immune system and essential virus fighting cells. Acquired Immunodeficiency Syndrome (AIDS) is the final stage of HIV infection. At this point of HIV people have badly damaged immune systems, which put them at risk for other disease and infections.
HIV and AIDS have affected millions of people throughout the world. Since 1981, there have been 25 million deaths due to AIDS involving men, women, and children. Presently there are 40 million people living with HIV and AIDS around the world and two million die each year from AIDS related illnesses. The Center for Disease Control estimates that one-third of the one million Americans living with HIV are not aware that they have it. The earliest known case of HIV was in 1959. It was discovered in a blood sample from a man in Kinshasa, Democratic Republic of the Congo. Looking further into the genetics of this blood sample researchers suggested that it had originated from a virus going back to the late 1940’s or early 1950’s. In 1999, researchers had discovered that HIV is derived from chimpanzees native to west equatorial Africa. This epidemic is spreading throughout countries and infecting 14 thousand victims every day. Learning about HIV includes knowing how to contract the virus, understanding most of the people it affects, how to prevent the spread of it, and knowing what treatments are available.
I have researched this topic through various sources and compiled pertinent information to provide adequate information on this. topic. The sym First of all, AIDS is caused by the retrovirus HIV. HIV stands for human immunodef- iciency virus. AIDS itself stands for acquired immune deficiency.