Cholesterol
High cholesterol is the best known of all the many threats to a healthy heart. When excess amounts fatty like plaque substance build up along the walls of the arteries, you face a significantly higher risk of a complete blockage, leading to a heart attack or stroke. At normal levels, cholesterol is not a bad thing. On the other hand, its an essential material used by the body to make cell walls and produce hormones, such as testosterone and estrogen. The body produces its own supply of cholesterol in the liver, it’s also found in various animal products such as meats, eggs, and, milk. Cholesterol only becomes a threat when the body can’t use or get rid of excessive amounts of it.
When one or several lipids combine with proteins this forms lipoproteins, these transport fat throughout the bloodstream. High-density lipoproteins, also known as HDL, carry fat away from body cells, therefore preventing its growth in the artery walls. Low-Density Lipoproteins, also known as LDL, contain a high amount of cholesterol and seem to help the build up of fatty materials in the artery walls. The situation that you should go for would be high HDL and low LDL levels. Your goal should be to keep your overall cholesterol at below 200, with LDL lower than 40, and your HDL should be at around 160. This will lower the risk of heart disease and other related problems with cholesterol.
The tendency to build up high cholesterol may run in families, but extremely high levels are usually the result of a poor diet high in saturated fats and calories, along with little or no exercise. In some cases, high levels of cholesterol may be associated with undiagnosed medical symptoms such as diabetes or low thyroid function. According to the American Heart Association, there would eventually be a 50 percent lower rate of heart disease if Americans would lower their blood cholesterol levels by 25 percent. These statements find confirmation in a 1984 report done by the National Heart, Lung and Blood Institution on the results of a 10 year study. It showed that for every 1 percent of lowered cholesterol, the chances of a heart attack are lowered by 2 percent.
High cholesterol rarely shows any warning signs. Soft, yellowish skin growths called xanthomas, usually in the area near the eyes. Some men develop impotence as the arteries begin to clog up.
Palpation of the liver may reveal liver masses or enlarged liver. According to the Stanford School of Medicine (2015), the normal liver may be slightly tender to palpitation.
My case study was based on a women name Margie. Margie is a 50 year-old women that frequently exercises and maintains a healthy eating habit. Even though Margie is a fit 50 year-old her cholesterol was well above average 222. Her trainer then recommended her to sign up for extra kickboxing class and maintain a vegetarian low fat diet, therefore her cholesterol would decease. About a month later she tested her cholesterol again and after the extra exercise, low fat diet her cholesterol was higher than the previous time at 230. Therefore, Margie attended the doctor where she was diagnosed with hypothyroidism.
It was to this respect that, the search could detect ‘’hypertension’’ as the leading risk factor for heart disease. And this preceded three quarters of heart failures cases as compared to coronary artery disease, which led to most heart failures in less than 40% of the cases. Also, an increase in left ventricular end-diastolic diameter became a mirror to the Framingham study as incident heart diseases in the individuals who are free from myocardial infarction. Although studies have shown that, the manifestation of heart failures can be present without the left ventricular systolic dysfunction, other risk factors could lead to that. Also, they (Framingham study) were able to detect ‘’too much of cholesterol’’ as a link to cardiovascular diseases. Moreover, research believed that has elevated among certain heart diseases such as coronary heart often leads to stroke, too high blood pressure among numerous patients. Having said that, the search discovered ‘’obesity’’ also as a concomitantly with hypertension which elevates lipids and diabetes versus questions on smoking behavior. Having said that, these risk factors are believed to have attributed to heart diseases. Therefore, it became a national concern to the general US population and that of the fourth director of Framingham heart study, William Castelli
Hypercholesterolemia is the presence of high levels of cholesterol in the blood. Cholesterol is a waxy fat-like substance and is a major class of lipid, so it gets into the blood by lipoproteins [1]. A high level of lipoproteins is unhealthy. A high level can result in an elevated risk of atherosclerosis and coronary heart disease [2]. The high levels of lipoproteins are often influenced by a combination of genetic and environmental factors such as obesity or dieting habits [2]. High cholesterol can be caused by mutations in the following genes: APOB, LDLR, LDLRAP1, and PCSK9 [3]. Mutations in the LDLR gene are responsible for causing familial hypercholesterolemia, which is the most commonly seen form of inherited high cholesterol [3]. The LDLR gene contains instructions for making LDL receptors or low-density lipoprotein receptors. LDL receptors play critical roles in regulating levels of cholesterol in the blood by removing low-density lipoproteins from the bloodstream. Mutations in the LDLR gene can make the amount of LDL receptors produced less than normal or affect their job of removing the low-density lipoproteins in the blood [4]. People who have these mutations will have higher levels of cholesterol. There are many ways that the environment can affect the levels of cholesterol in the blood. Reducing the amount of dietary fat you consume lowers the total amount of cholesterol in the blood [5]. Sucrose and fructose can raise the amount of LDL in the blood. Reducing fatty foods will however lower the amount of LDL [5]. Having a healthy body and maintaining physical exercise plays a key role in keeping your cholesterol at a healthy level. If you are overweight or obese you can lower your cholesterol levels by simply losing ...
CAD is a leading cause of morbidity and mortality throughout the worldwide. The prevalence of biological and metabolic risk factors were also found to be high in development of coronary artery disease. Patients with hypercholesterolemia are at increased risk to experience cardiovascular events and to die from vascular disease [2]. .Statins, among the most commonly prescribed drugs worldwide, are cholesterol let downing agents used to manage cardiovascular and coronary heart diseases and to treat hypercholesterolemia. Statin’s therapy ...
Several effects of steroid use have been identified. These include an increase in low density lipoprotein (LDL) cholesterol and a decrease in high density lipoprotein (HDL) cholesterol. These lipid changes if allowed to continue over long periods of time could result in coronary heart disease (6). Some other side effects of steroids in men include shrinking of the testicles; reduced sperm count, infertility, baldness, development of breasts, and increased risk of pro...
Symptoms of elephantiasis are enlargement and swelling of a part of the body due to the blockage of the lymphatic nodes. The lymphatic system is not able to take out the extra fluid of the body which causes an accumulation of body fluid. The arms and legs are the most affected areas in the body. It can swell to more than three times of its normal shape. Affected areas will have malformed shapes; skin and tissue will become thick and appear to look like an elephant’s leg. The skin of the affected areas becomes extremely dry, thickened (hyperkeratosis), and discolored. Other symptoms may include Fever, chills, and a feeling of sickness. Elephantiasis may affect the male and female external genital area. Some male suffer from enlargement of the scrotum, in some cases scrotum can become abnormally enlarged and can weigh over 100 lb. The penis may be hidden under the skin. In some women the external area of the genitalia will appear thickened and ulcerated rough skin may develop. The breasts may become enlarged. Infected individuals are susceptible to bacterial and fungal due to the damage of the lymphatic system. Infections may become worsen due to the lack of immunity caused by a damaged lymphatic system. People affected by this disease may experience severe pain and a burning
You look in the mirror and see that your skin and eyes seem a yellowish color, your legs and ankles are swollen, you have abdominal pain and swelling, your skin is also itchy, you have dark urine, and notice that your stool is a pale color. What do these symptoms mean? These are symptoms of damage to the liver. There are many ways to damage your liver like the use of alcohol, but a way you may not be aware of is the use of medication. Some medications when used repeatedly can cause liver damage, such as acetaminophen, also known as Tylenol.
This is because the tissue swells around the eyes and suffer from hyperthyroidism, muscular weakness, and rapid pulse and develop a reddish, painless skin rash. People who show signs and symptoms usually are either mild or severe. It all depends on the activity level of the thyroid. The disease affects the immune system itself and no other places. Symptoms usually develop over a 3-month period. The carrier usually is not aware that they have Graves’ disease. They usually find out when the symptoms are severe. The common signs are weight loss, tremors, feeling of being hot, and palpitations. (www.ncbi.nlm.nih.org). The less common sign that can occur as well. They are over activity of the intestines, which leads to frequent bowl movements. Sometimes the breakdown of protein in muscles can lead to extreme weakness, which causes trouble breathing and limited endurance. (The Thyroid Book). The thought of having Graves’ disease can be disturbing. Mood swings and thinking impairment can be difficult to handle. Crying spells, depression and feeling down are common. The patient’s personality can be different and will change. This could make work difficult and hard to keep. Generally, a person with Graves’ disease will have a thyroid that is enlarged but will not have any pain from it. This is called a goiter and can be seen in the neck most of the time. Sometime you cannot see the goiter but by feeling and examining the neck, it can be detected.
Hyperlipidemia or increased cholesterol builds up causing narrowing in the arteries, which reduces oxygen rich blood flow to the heart and tissues, also increasing the risk for myocardial infarction. Obesity increases the risk of developing diabetes, high blood pressure, and hyperlipidemia, increasing the risk of atherosclerosis, and therefore increasing
of fatty substances on the inside wall of the arteries). It is not caused by
After a matter of time you will begin to notice some symptoms. The most common symptoms are: weakness, fatigue, loss of appetite, weight loss, yellowing of the skin, itchy skin, ascites, bleeding, bruising, and mental health changes. (Kenny, Tim ) Cirrhosis can also cause complications to other areas of the body. Ascites is fluid that is present on the inside cavity of the abdomen. Cirrhosis can cause the fluid to build up between the layers of the abdomen and make it become enlarged. Portal Hypertension is also caused by having cirrhosis. The blood flow slows down in the major blood vessel and creates pressure on the inside of the vein. The blood then returns to the heart by different blood vessels. When this happens, the increased blood flowing through these vessels become swollen causing varices. The varices can be easily broken because of the high blood pressure flow and could ultimately cause death. Also, when the liver is unable to remove toxins from the blood, the loss of brain function can occur. This is called Hepatic Encephalopathy. This occurs when the liver does not detoxify and breakdown body substances and the toxins build up in the bloodstream. Sedatives and narcotics can make Encephalopathy worse, so liver disease patients are not allowed to take these medicines. (Liver Anatomy
Familial hypercholesterolemia, also known as familial hyperlipoproteinemia, is an autosomal genetic disorder that leads to increased low-density lipoprotein level in the blood which is known as “the bad cholesterol “. The disorder starts at birth and the responsible gene of this medical condition is inherited. Familial hypercholesterolemia can be diagnosed through regular screening blood work that reveal extremely elevated total cholesterol and low-density lipoprotein level in the blood; Patients can have total range of cholesterol levels in the 350-550 mg/dL. Also, the physician, during a physical examination, can suggest familial hypercholesterolemia from certain findings such as xanthelasma, tendon xanthomas, or tuberous xanthomas. Recently, molecular testing methods are being used
My cholesterol was 699.83 mg, and since it is hard to determine between HDL and LDL through a food tracking application there was no Daily Recommended Intake. Yet, for a 2,000-calorie diet, it suggests 653mg as a maximum. I should reduce my cholesterol levels, because high cholesterol levels can increase risk of heart disease and stroke due to the plaque that can build up in the arteries. My total fat levels were 251% above my Daily Recommended Intake, and I should reduce total fat intake. Of the fat intake, I should reduce saturated fat the most, which was 138% of my Daily Recommended Intake. Saturated fats can increase risk for heart disease by increasing blood cholesterol. To reduce my fat intake I can replace foods like hamburgers with a leaner cut of meat, or chicken. I can reduce fat levels by using less butter to cook my meals, and less cheese. A good option would be a whole grain bread with turkey deli meat, which only has 1.4g of fat per serving. My sodium levels are also abnormally high; I consumed 7,053 mg of sodium, which is 5,553 mg over my Daily Recommended Intake. High sodium diets can increase blood pressure, which can lead to heart disease. To reduce sodium in my diet I can consume less packaged products, mostly meat products and choose a freshly cooked option. I should stay clear of frozen vegetables that have “fresh frozen” because they do not include added sodium. When deciding condiments, I should stay clear of high sodium products such as ketchup, soy sauce, dips and mustard. An easy away to identify food with recommended sodium levels in a grocery store is the “American Heart Association’s Heart-Check mark”. I consume a supplemental protein shake after each workout within thirty minutes to maximize my recovery and absorption of protein. I also have 25g of supplemental whey protein, and 40 grams of casein protein. Both of these products are
My DRI of cholesterol was maxed at 300mg and my intake was 267mg. Still relatively high so could start consuming Oatmeal for breakfast in which reduces your low-density lipoprotein (LDL), the "bad" cholesterol. Also, I...