Hepatitis Case Studies

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The patient first visited his physician with malaise that had worsened during the last months and we can see from his laboratory results that the underlying cause for the discomfort was due to HCV. He had a known history of drug addiction which suggests the cause of contraction was through the sharing of unsterilized needles resulting in the blood-to-blood contact of another individual with the virus. He had signs of mild jaundice, a yellowish pigmentation of the skin, whites of the eye and other mucous membranes due to high blood bilirubin (Tandon et al., 2015), which aided in the diagnosis of hepatitis as jaundice is a symptom of acute hepatitis.
5 types of hepatitis, HCV was diagnosed as only the testing of hcv antibodies and hcv-rna came back as positive. The monitorinf of anti-HCV antibody throughout allowed the surveillance of the progress of the disease.

The genotype of HCV was identified from the hypervariable region of envelope E2 gene of the virus because HVR1 can be used both to identify …show more content…

These symptoms helped diagnose him as ascites is a result of increased hydrostatic pressure due to cirrhosis and is the result of excess fluid in the peritoneal cavity (Leung and Wong, 2011), whilst Splenomegaly is the abnormal enlargement of the spleen due to liver disease (Pozo et al., 2009). But, the presence of ascites is a poor prognostic sign of cirrhosis (Gines et al., 2004) as over a 10-year clinical course, the incidence of ascites in cirrhosis has been reported to be 50% and there is almost a 50% 2-year survival rate in patients with advanced ascites (Gines et al., 1987). The fibrous scarring and nodular lymphocytic aggregates seen in the liver biopsy support the diagnosis of hepatitis C with cirrhosis as fibrous scarring is a sign of cirrhosis and the gathering of lymphocytes is a sign of hepatitis

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