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Basic pathology pancreatitis
Pancreatitis questions
Pancreatitis case examples
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Recommended: Basic pathology pancreatitis
What is Pancreatitis? The pancreas is a large gland that is located in the upper abdomen that secretes digestive juices, and releases insulin and glucagon into the bloodstream. Pancreatitis is a medical term for inflammation of the pancreas. When the pancreas is inflamed, it can progress to swelling of the gland, and surrounding blood vessels, bleeding, infection, and damage to the gland. It occurs when digestives enzymes start digesting the pancreas itself. Pancreatitis has two types; acute or chronic and either type can be life-threatening and have some serious complications.
What are the causes? Alcohol abuse and gallstones are the two main causes of pancreatitis, accounting for 80% to 90% of all individuals diagnosed with the condition.
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Some may feel pain but most do not. For those who experience pain, it is usually constant and disabling and it goes away as the condition worsens. This lack of pain is considered as a bad sign because it probably means that the pancreas has stopped working. Other symptoms are related to long-term complications such as inability to produce insulin, inability to digest food, bleeding and liver problems.
Risk Factors Excessive alcohol intake and gallstones are the major risk factors for pancreatitis. Other risk factors include a family history of pancreatitis, high levels of fat in the blood, cigarette smoking, certain inherited disease such as cystic fibrosis and taking certain medications.
Diagnosis
When a health care professional identifies symptoms of pancreatitis, specific questions are asked about the person’s symptoms, lifestyle and habits, and medical and surgical history. These types of questions will help to rule out some conditions and make the correct diagnosis. In most cases, however, laboratory tests are needed. The tests will determine the function of several body systems including pancreas, liver and kidney functions, signs of infections, blood cell counts, and blood sugar, electrolyte levels and calcium level. Results of the blood tests may be inadequate if the pancreas is still making digestive enzymes and
In conclusion, 1 out of 10 people are at risk for gallbladder attacks. Gallstones are the main reason for these attacks. If you’re older, a female or overweight and have a sedentary lifestyle, a diet high in fat and sugar, you pose to be a potential candidate for these painful attacks.
Crohn’s disease is a disease that causes inflammation, swelling, and irritation to any part of the digestive tract which is also known as the gastrointestinal tract or GI tract. The disease most commonly targets the ileum which is a part in the small intestine. The digestive tract is organs that connect your mouth to your anus and it releases hormones and enzymes for the digestion in food. The inflammation caused by the disease goes deep into the lining of the digestive tract. It creates a stricture in the small intestine which is a narrowing of the pathway that can slow the movement of food through the intestine. The stricture can then move to large intestine which can cause many problems for absorption. When the disease causes the intestine to swell it can also be very problematic because the large intestine wouldn’t be able to function properly. Crohn’s disease is considered as an inflammatory bowel disease.
Crohn’s Disease and Ulcerative Colitis are both in a category of diseases called Inflammatory Bowel Diseases. This is a classification of disease in which inflammation forms in a part of the digestive tract, known as the gastrointestinal tract or GI tract, of the patient. The immune system then treats this area of inflammation as a foreign pathogen and attacks it. The causes of both of these diseases are currently unknown to the medical world.
Liver disease resulting from alcohol affects more than two million Americans and is one of the primary causes of illness and death. The liver frees the body of harmful substances, such as alcohol. While the liver breaks down alcohol, it produces toxins that can be even more dangerous than the alcohol consumed (“Beyond Hangovers: Understanding Alcohol's Impact on Your Health” 13). “These by-products damage liver cells, promote inflammation, and weaken the body’s natural defenses. Eventually, these problems can disrupt the body’s metabolism and impair the function of other organs” (“Beyond Hangovers: Understanding Alcohol’s Impact on Your Health” 13).
This case study is about Abdul Chidiac, a 51 year old male, married with 4 children. He had a medical history of hypertension, hypercholesterolaemia and cirrhosis with two admissions in the last six months. He is a smoker and drinks beer, 5-6 bottles per day. As Carithers & McClain (2010) explained the patient’s medical history is another indicator of the risk for cirrhosis; the progression to cirrhosis is adaptable and may take time over weeks or many years. Cirrhosis is a liver disease characterized by permanent scarring of the liver that interferes with its normal functions including alcoholism. Most people who drink large amounts of alcohol cause harm to the liver in some way (Heidelbaugh & Bruderly, 2006). The cause of cirrhosis is not yet known, but the connection between cirrhosis and excessive alcohol ingestion is established (Jenkins & Johnson, 2010). Common causes of cirrhosis include: alcohol abuse, hepatitis B infection, hepatitis C infection and non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (Schuppan & Afdhal, 2008).
As a result, the pancreatic juices become thick and viscous potentially creating a plug that can cause a biliary duct blockage (2,14, 15). Duct obstruction from pancreatic juice and its content increases pressure, leading to distension of the duct also (13, 14, 15). At a cellular level, membrane trafficking becomes chaotic, potentially leading to Trypsinogen activation into trypsin, initiating the cascade of digestive enzyme activation and autodigestion of the pancreas, causing AP (13,14, 15). Alcohol abuse further prompts acinar cells to release inflammatory cytokines, attracting a strong immune reaction causing pancreatic tissue destruction (13,14,
...e disease process of pancreatitis. This situation has changed my practice by looking more in-depth into disease processes and the complications I could be faced with. I need to beware of how conditions can change and always be one step ahead in foreseeing these changes to be able to deal with these situations when they arise.
Risk factors for both Cholecystitis /cholelithiasis includes obesity; rapid weight loss in obese individuals; middle age; female gender; use of oral contraceptives; American Indian ancestry; gallbladder, pancreatic, or ileal disease; low HDL cholesterol level and hypertriglyceridemia; and gene-environmental interactions (Doig &Huether, 2014).
Diabetes is a disease that I came across when researching my maternal side of my family history. Diabetes is a disease that affects your pancreas an important organ in regulating blood sugar. When a person has diabetes there are two ways it can affect the pancreas because there are two types of the disease. Type-1 diabetes affects the pancreas by not allowing the body to produce enough insulin to keep the body’s blood sugar at a healthy number. The opposite is for Type-2 which produces too much insulin and gives the body too much insulin keeping the blood sugar number above healthy (Type-2).
There are no symptoms in the early stages of pancreatic cancer. Later stages include symptoms such as loss of appetite, unexplained weight-loss, pain in abdomen or middle back, dark urine, itchy skin,
Many people that are alcoholics generally encounter heart attacks and liver disease. When you start to encounter a heart attack you will suddenly start to feel agony in your heart. Heart attacks can be threatening because it will cause you to suffer so much pain and the pain doesn’t go away even when you are resting and taking medicine. Heart attacks occurs when the coronary artery obtains a blood clots that clogs up the blood flow to the heart which cause the muscles in the heart to weaken and eventually causes the heart fail. Now when you encounter liver disease you are rolling toward a world of trouble you will start to lose weight, lose energy, and ect but it can get worst. Some alcoholics get the liver disease after many years of heavily consuming alcohol. Alcoholics can also encounter cancer in mouth & throat but not many alcoholics develop cancer from heavy drinking, it develop most when you smoke acreage of tobacco. Cancer in the throat is basically when the cells in your throat develops a genetic mutation. Cancer in the mouth is when the cells in your lips have a genetic
How To Manage Type 1 Diabetes? Summary: Type 1 disease is a major illness that used to affect kids and adolescences, but now it’s affecting adults as well. To control your diabetes, you need to know all the things related to it. Learn how to manage type 1 diabetes, so that you live a long & healthy life.
Ulcerative colitis, or UC, is a chronic gastrointestinal disease that causes inflammation and ulcers in the lining of the large intestine. It causes ulcers in the colon and rectum. Ulcerative colitis is one of two forms of inflammatory bowel disease. In UC, the inflammation from the ulcers breaks down the lining of the colon and causes bleeding and discomfort in the abdomen.
Alcoholism, diabetes, anti- cancer therapy and ingestion of toxins are among the several known causes of
The pancreas uses these two hormones in order to monitor blood glucose levels. After a meal, blood glucose usually rises. This is when insulin secretion will start (Nussey S, Whitehead S. “Endocrinology: An Integrated Approach”). Consequently, blood glucose decrease to the normal range. This is how insulin maintains blood levels when is high. However, when blood level falls below normal range, glucagon comes into play. Low blood glucose occurs usually when hungry and during exercise. This will then triggers glucagon secretion. When blood level falls, the body goes into imbalance. Hence is why in order to maintain homeostasis glucagon is crucial. The body will tell the pancreas to increase more glucose and the pancreas will secrete glucagon by taking glycogen from the liver to produce glucose. The glucose will produce energy and will make blood glucose concentration increase (Homeostasis of Insulin and Glucose, Abpischools.org). When the pancreas cannot maintain homeostasis, many problems will arise in the body. When the pancreas fails to produce insulin, type 1 and 2 diabetes can occur. For those with type 1 diabetes, insulin injections will be needed in order to regulate blood glucose level, otherwise, glucose levels will be out of control. For type 2 diabetes, they are not insulin dependent like type 1, however, the body does not create enough in the body. When blood glucose