Essay On Hippocampal Abnormality

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This paper will cover the hippocampal abnormalities and the effects of emotional and traumatic events in DID patients. Causes of DID are not understood, but 90 to 95 percent of patients report childhood physical and/or sexual abuse. Many therapists believe that the individuals generate alternate personalities or “alters” as a front line defense against prolonged emotional stress. The “alters” give an escape among other things. (Garrett, B 2014, p. 508). Emotion and trauma do a lot to a persons brain processing and structure. In the article “Abnormal Hippocampal Morphology in Dissociative Identity Disorder and Post-Traumatic Stress Disorder Correlates with Childhood Trauma and Dissociative Symptoms” they explored hippocampal morphological correlation of childhood traumatization and dissociative symptoms in both dissociative identity disorder (DID) and post-traumatic stress disorder (PTSD) patients. It was hypothesized that (1) both DID and PTSD patients compared to healthy control would have smaller global hippocampal volume, regional volumetric abnormalities and shape deformations in different hippocampal subfields, (2) global hippocampal volume, regional volume …show more content…

The study compared hippocampal and amygdala volumes in patients with DID compared with healthy subjects. The patients with DID in the study showed a 19.2% smaller hippocampal volume compared to the healthy subjects. N-methyl-D-aspartic acid (NMDA) receptors are highly concentrated in the hippocampus, the article also hypothesized that stress, acting through NMDA receptors in the hippocampus, may mediate symptoms of dissociation. The finding suggest that DID is associated with relatively greater volume reductions in the amygdala than in the hippocampus. Stress-related dissociative symptoms happen to occur in many individuals with

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