Brain Reserve Theory Essay

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The brain reserve theory is based on the idea that biological attributes, such as brain size, synaptic connectivity, or neuronal count, lead to protective and compensatory mechanisms within the brain in the face of pathology. The theory finds that larger brains can sustain more damage before clinical deficits emerge due the sufficient neural substrate that is remaining to support normal functioning (Dekhtyar et al., 2015; Steffener & Stern, 2012). This neural substrate is thought to be a buffer created by an increased number of neurons and larger pyramidal neurons (Reed et al., 2010; Schweizer, Ware, Fischer, Craik, & Bialystok, 2012). Education, intelligence, and/ or environmental stimulation are thought to contribute the most to this increased neuronal count. The brain reserve theory suggests that intelligence is the most valid …show more content…

The environment plays a key role in influencing plasticity as it can respond to stimuli that will lead to the development of neurons to some regions of the brain, and therefore influence brain reserve (Fratiglioni &Wang, 2007). Enriched environments, including mental and physical stimulation, may promote brain development through the ‘use it or lose it’ theory. This theory implies that by actively engaging in stimulating activity during life, one can see an increase in neuronal development, but if one were to continually not be engaged then they would lose this ability (Schmand et al., 1997). Even though every individual has brain plasticity, the brain reserve theory hypothesizes that it is also the variations in every individual’s brain anatomy that will lead to different levels of its ability to handle the pathological damages before leading to the presentation of the clinical manifestations of Alzheimer’s disease (Bartres-Faz & Arenaza-Urquijo,

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