Arterial Hypertension Pathophysiology

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Foëx, P., et al; (2004). Hypertension: pathophysiology and treatment. Arterial hypertension is an important reason of morbidity and mortality because of its connection with coronary heart disease, cerebro-vascular disease and renal disease. The degree of target organ involvement (i.e. heart, kidneys and brain) determines results. Studies in North America have shown that hypertension is a major reason of 500000 strokes (250 000 deaths) and 1000 000 myocardial imperfections (500000 deaths) per year. Continuous National survey reveals that hypertension is often not detected and, when diagnosed, is often improperly treated. Among hypertensive patients, only 25% cases are well handled. This is true for isolated systolic hypertension. Yet the occurrence …show more content…

There is prominence on the risk associated with systolic hypertension as the level of systolic pressure is a good indicator of coronary and cerebrovascular risk, especially in the elder people. Treatment of systolic hypertension is effective in terms of control of blood pressure and reduced morbidity, especially in older patients with high risk profile. Over the past years, the treatment of hypertension has changed with the recognition that there is no limit below which increased blood pressure, causes no threat to health. Recent suggestions, alongwith the British Hypertension Society, clarify that cure for isolated systolic hypertension is as important as that of systolic and diastolic hypertension. The level above which hypertension should be treated to prevent long-term complications is 140/90 mm Hg. Indeed, in Stage 1 hypertension, treatment of isolated systolic hypertension (systolic 140– 159 mm Hg, diastolic <90 mm Hg), reduces the occurrence of left ventricular hypertrophy, an indicator of future morbidity and

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