Alzheimers The Unsolved Mystery

895 Words2 Pages
bulb-icon

Recommended: Alzheimer's disease symptoms essay

Alzheimer's: The Unsolved Mystery

Absentmindedness, with questions having to be repeated, trouble following conversations, or remembering people's names, sound familiar? These are classic early stage symptoms of Alzheimer's.
Alzheimer's is a type of dementia in which parts of the brain stop working, causing memory loss, and instability in judgement, reasoning and emotions. Dementia, such as Alzheimer's is usually more frequent in elderly people. Approximately 15 percent of people who are over 65 will develop some form of dementia; by the age of 85 that percentage increases by at least 35 percent. Alzheimer's is the most common dementia, nearly four million Americans suffer from it.
Alzheimer's is a very complex disease. So complex that very little has been discovered about it but that is rapidly changing. Findings from epidemiology, genetics, molecular and cell biology are fitting together in the Alzheimer's puzzle, helping researchers to identify some of the mechanisms that underlie it. Alzheimer's starts because the normal processing of certain proteins goes terribly wrong. This causes brain cells and the spaces between them to be cluttered with pieces of toxic protein. Closer investigating with microscopes has revealed a loss of nerve cells in certain regions of the brain. Some of these dying nerve cells communicate using the neurotransmitter acetylcholine, these compounds eventually break down by an enzyme called acetylcholinesterase. Also responsible for Alzheimer's are clusters of proteins in the brain which come in two forms: those found inside the nerve cells and those found in between the cells.
The clusters inside the cells look like pairs of threads wound around each other in a helix. The tangles consist of a protein called tau. Tau binds to another protein called tubulin. Tubulin then forms structures called microtubules which run through cells, giving support and shape. Also the microtubules provide pathways for nutrients and other molecules to travel through.
The main problem is that researchers can't quite figure out how Alzheimer's is started. Some the leads are its inherited genetically, is caused by major head injury, poor earl...

... middle of paper ...

... on this amazingly complex disease. The BAPP theory only accounts for five percent of all Alzheimer's cases. Some may believe that this is a small step in uncovering the mystery of Alzheimer's but I believe it will be a huge one after its throughly examined. The BAPP discovery should help open the door for Alzheimer's and reveal more about how the disease functions and what exactly causes it. For those people who are infected with the disease they can only sit in agony and hope that a more powerful insight is made for the sake of future generations. It is believed that by 2025 more than 22 million people world wide will be infected with Alzheimer's and as the average life span lengthens the percentage only gets steeper.
Alzheimer's is the worst kind of disease. It not only infects the being with which it is in but it also affects the people who know and love that person. For mankind's sake hopefully more work will be put into establishing a cure for this awful dementia.

Bibliography:
Author: Peter H. ST. George-Hyslop , Scientific American, December 2000

Show More
Related

  • Essay On Race And Biopower

    1217 Words  | 3 Pages

    For at least three decades race, gender and biopower have all been linked together. The three terms used, are frameworks installed by governments to manage the population by categorizing, regulating and controlling its subjects. Race, gender and biopower are intertwined to illuminate the treatment of the minority for centuries. The mistreatment, discrimination and suffering experienced by the minorities throughout history is evident in the texts provided.

    Read More

  • The Black Death

    2054 Words  | 5 Pages

    The bubonic plague was the most commonly seen form of the Black Death. Which had a mortality rate of 30-70%. The symptoms were enlarged and inflamed lymph nodes (around armpits, neck and groin). The term "bubonic" refers to the characteristic bubo or enlarged lymphatic gland. Victims were subject to headaches, nausea, aching joints, fever of 101-105 degrees, vomiting, and a general feeling of illness. Symptoms took from 1-7 days to appear.

    Read More

  • The Black Plague In The Middle Ages

    1725 Words  | 4 Pages

    The Black Plague was brought upon Europe through the fleas that were on the bodies of rats. As soon as an infected flea bites a single human, anywhere in the world, they are infected with the deadly virus that the fleas carry. The rats with fleas would climb up into the trade boats and get off at another place spreading the disease to many places in the Middle Ages. But the rats were also affected by the fleas’ virus, the rats could survive with a few bacteria in them but eventually, they will die after a few days of also being infected like the humans. The Black Plague was out of three plagues but it was mostly of the bubonic plague which are the least toxic out of the other plague but it is still highly lethal, killing 50% to 60% of its victims, the pneumonic plague which affects the lungs, and the septicaemic plague which affects the blood. The Black plague is one of the most known plagues in history not only for killing millions of people on earth but also because of it spreading rapidly throughout the

    Read More

  • Alzheimers Disease

    2696 Words  | 6 Pages

    performance that involves, but is not limited to, a loss in at least 2 of the

    Read More

  • Alzheimers Disease

    1096 Words  | 3 Pages

    Alzheimer’s disease is a complex illness that affects the brain tissue directly and undergoes gradual memory and behavioral changes which makes it difficult to diagnose. It is known to be the most common form of dementia and is irreversible. Over four million older Americans have Alzheimer’s, and that number is expected to triple in the next twenty years as more people live into their eighties and nineties. (Johnson, 1989). There is still no cure for Alzheimer’s but throughout the past few years a lot of progress has been made.

    Read More

  • The Plague - The Black Death

    1428 Words  | 3 Pages

    The plague was spread by fleas, which were not effected by the disease. Fleas first infected the rats, which lived off garbage and sewage. The rats then spread the infection to the humans. Rats were a common sight in the cities, due to the poor sanitary conditions, so no one suspected them (www.tartans.com). In the winter the plague seemed to disappear, but only because fleas were dormant then. Each spring, the plague attacked again, killing new victims (www.byu.edu). The effects of the plague were devastating. After just five years, twenty-five million people were dead - one third of Europe's population. Once people were infected they infected others very rapidly. As a result, in order to avoid the disease, many fled to the countryside where the lower population density helped to decrease the speed at which the disease spread (www.tartans.com). From a person's time of infection to his or her death was less than one week (www.home.nycap.rr.com). The plague became known as "The Black Death" because of the discoloration of the skin and black enlarged lymph nodes that appeared on the second day of contracting the disease. The term "The Black Death" was not invented until after 1800. Contemporaries called it "the pestilence" (Cantor 7).

    Read More

  • The Black Death

    1673 Words  | 4 Pages

    The plague took on three different forms, each with its own unique way of killing. The most common, bubonic, was considered the mildest form, with a mortality rate of thirty to seventy-five percent. A person with this would be seen with enlarged lymph nodes in the neck, arm and groin regions, with headaches, nausea, body aches, and a high fever. The pneumonic plague was the second most commonly seen form of the Black Death. Only five percent of its victim’s survived, infecting the lungs, causing a person to cough and vomit blood. The least common form, but most deadly, with a one hundred percent death rate was the septicemic plague. Even today, if a person were to come up with this form of the...

    Read More

  • The Black Death

    1298 Words  | 3 Pages

    Graveyards were full, medicine failed, parents abandoned ill children and in just six months, millions had died. It was the beginning of the Black Death. It was a deadly plague that spread through Europe and Asia from the mid 1330’s -50’s. The cause of death for twenty million people, the survivors thought it was God’s anger at something they had done and, therefore, the end of the world. In Venice, ninety thousand died and in Florence, half the population. There were three types of the plague. The Bubonic plague was the most common, the Pneumonic Plague was less common and the Septicaemic Plague was the most deadly and rarest of them all.

    Read More

  • Alzheimers Disease

    942 Words  | 2 Pages

    Alzheimer’s disease is a form of dementia which is a brain disorder that impairs mental functioning. Dementia attacks the part of the brain which controls memory, language, and thought. It makes everyday tasks like remembering to brushing your teeth, or to pay your bills next to impossible to do, which is why so many people who are diagnosed with this disease are in complete care. This disease has different phases, the first being slight forgetfulness and then the persons emotions may heighten as well as language impairment, violent outbursts, loss of bladder control and from there it keeps getting worse until complete dysfunction of the brain occurs and eventually death, which most of the time is the result of infection.

    Read More

  • The Plague

    1243 Words  | 3 Pages

    The Plague, also known as the Black Death, or the Bubonic Plague, which struck in 1346, and again in 1361-62, ravaged all of Europe to the extent of bringing gruesome death to millions people of the Middle Ages. It was a combination of bubonic, septicemia, and pneumonic plague strains that started in the east and worked it’s way west, but never left its native home. One of the things that made the plague one of the worst was that there were outbreaks almost every ten years but still restricted to Europe. It is thought that one third to one half of the population in Europe could have possibly died due to the plague with some towns of a death rate of up to 30 or 40 percent. Very few that were infected with the plague actually survived more than one month after receiving the disease.

    Read More

  • Alzheimers Disease

    1275 Words  | 3 Pages

    Well no one knows exactly the development of this debilitating disease of the brain. But recent advances have produced several clues as to why. how it is born. Initially when we study the brain of an Alzheimer's victim, we focus on two specific areas. One is the cortex of the frontal and cerebral.

    Read More

  • Alzheimer's Disease

    1070 Words  | 3 Pages

    Alzheimer’s disease is a progressive degenerative disease that attacks the brain and results in impaired memory, thinking and behavior. Alzheimer’s is the most common form of dementia. Dementia is the lost of thinking, remembering and reasoning so bad it screws up ability to do daily functions and eventually resolves in death. Dr. Alois Alzheimer’s first discovered the disease in 1906. Since then research has developed a deeper understanding of the changes in the brain. Warning sign’s of Alzheimer's are memory loss that affects home and job skills, problem in speaking, poor judgment, and difficulty in learning. The last stage of Alzheimer's disease is when you’re unable to take care of yourself. The disease can last from 3 to 20 years from the time of onset of symptoms.      Alzheimer’s disease affects as many as 4 million Americans. It can affect almost any age but still is more common in the ederly. As ageing population continues to increase, so does the disease. Today, 3% of the people ages 65 to 75 have alzheimer’s, 10% of those aged 75 to 85 have alzheimer’s and half the age 85 may have it to. Without a new cure it is estimated that alzheimers will affect over 14 million people by 2050. The elderly are the most infected with the disease and its still spreading. Other disease in common with Alzheimer’s is multi-infract dementia, Huntington’s disease, Pick’s disease, and Parkinson disease. People wonder if Alzheimer is genetic “meaning runs in families” the answer is the evidence isn't clear. Doctors and Physicians say if you have a by blood family member with Alzheimer's there's a slightly greater chance of getting or having the Alzheimer's disease. Many wonder if memory loss is a natural part of aging. The answer is yes and no, everyone has forgotten where he or she parked their car or the name of an acquaintance a one time or another. And many healthy individuals are less able to remember certain kinds of information as they get older. The symptoms of Alzheimer's disease are much more severe than simple memory lapses. This chart will kinda help you understand the difference.

    Read More

  • Alzheimer’s Disease

    2552 Words  | 6 Pages

    Scientists know that Alzheimer disease is characterized by a gradual spread of sticky plaques and clumps of tangled fibers that disrupt the organization of nerve cells in the brain. However , a definite cause, prevention, or cause has not been found.

    Read More

  • Black Death Essay

    1200 Words  | 3 Pages

    As you may figure viral deadly diseases such as malaria, HIV, and Lung Cancer have killed millions within the years of Human existence, but the one in particular to cause a major impact in the world’s history of sicknesses is The Black Death, formally known as the Bubonic Plague. The Bubonic Plague wasn’t the longest epidemic. The timeline that the disease was present, single handedly slaughtered 25 million people of the vulnerable population in Europe. The childhood nursery rhyme song “Ring around the rosies, pocket full of posies”, discreetly demonstrates the red rash symptomatic of infection and holding flowers under one's nose to combat the smell of sickness and dead bodies.(Ainsworth 64) The symptoms of the disease were airborne and highly contagious and could spread viciously to whomever that came in touching distance of an infected individual. The Black Death put SARS and AIDS in a lower caparison inquiring that they all have caused a death domino effect.(Ainsworth 64) The year of 1333 is when the plague originally geared up into severe sweeps starting in China with the international trading route occurring between constantinople and the mediterranean near the black sea. The living conditions people lived under helped the spread of the disease greatly.

    Read More

  • The Black Death Pandemic

    951 Words  | 2 Pages

    This pandemic first appeared in the city-states of Italy and spread across Europe culminating in the deaths of 25,000,000 people. It is now known that the plague originated in China and inner Asia and that one of the reasons it was so devastating was because of the famine that Europe had just started to recover from.It is also now known that the Black Death was the result of the bacteria yerinia pestis, a bacteria that can cause swelling of the lymph glands in the armpits, the groin, and the neck of people infected with the virus. No particular social class station faith or age group escaped the ravages and people became hungry for answers from the Church. This plague was so devastating Europe’s population did not reach its pre-1347 level until the 16th century.

    Read More

More about Alzheimers The Unsolved Mystery

Open Document