The Questions Surrounding the Breast Cancer Genes
The process of unraveling the mysteries of the human genome creates enormous possibilities in the world of science. Knowing where on our chromosomes a specific gene lies allows scientists to look inside the human body with more intensity than any X-ray could ever achieve. By analyzing the genetic make-up of human beings, scientists can track diseases back to their most fundamental stages. In recent years, scientists have discovered two genes that play a role in the development of various kinds of cancer in both men and women. With the additional ability to test individuals for their possession of deformed copies of these genes, many ethical questions have been raised. Although the majority of objections surrounding these tests seem to stem from economic and policy issues, there still exist social concerns as well. In time, these issues will have to be dealt with, because as has become increasingly the case, scientific developments preceed, rather than follow, serious ethical and legal thought.
In a healthy body, every one of the 30 trillion cells work together to regulate the transfer of information, movement, and countless other processes. One of the most crucial functions of each cell, however, is to regulate the cell growth itself and of neighboring cells. This is accomplished by creating checks on cell growth, such that no cell is to reproduce unless instructed to do so by those cells around it. When placed in a petri dish with food, a single cell will divide until the copies begin to reach the walls and come in contact with one another. At this point, they will exhibit the property of contact inhibition and will stop growing. Cancer cells, however, "violate this scheme...
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...Impact of Genetics on the Health Care in the United States," Biology 4, Dartmouth College, 13 February 1997.
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The “Era of Good Feelings,” beginning after the war of 1812 and lasting into the 1820s, is typically represented as a positive time in American history full of nationalism. However, in considering this time period, one remember to examine both the positive nationalistic perspective and the negative sectionalist perspective. Socially, after the war of 1812, the American morale was strengthened and nationalism grew. Politically, the collapse of the Federalist party after the Hartford convention lead to a more united voting population, having only one viable party to vote for. Economically, the national bank expanded its power and protective tariffs were issued, which were looked upon negatively in the south, causing division
White, Mary. “Making Responsible Decisions: An Interpretive Ethic for Genetic Decisionmaking.” The Hastings Center Report 29.1 Jan./Feb. (1999): 14-21.
The Era of Good Feelings was the name applied to the period in the United States corresponding with the term of President James Monroe, following the war of 1812. Shortly after he was put into office, his term was known as the Era of Good Feelings. However, it is clear that the Era of Good Feelings was mislabeled because although there was still a sense of nationalism, it was overshadowed by sectional conflict over the second bank, the tariff, and the demand for slavery.
The more we know about genetics and the building blocks of life the closer we get to being capable of cloning a human. The study of chromosomes and DNA strains has been going on for years. In 1990, the Unites States Government founded the Human Genome Project (HGP). This program was to research and study the estimated 80,000 human genes and determine the sequences of 3 billion DNA molecules. Knowing and being able to examine each sequence could change how humans respond to diseases, viruses, and toxins common to everyday life. With the technology of today the HGP expects to have a blueprint of all human DNA sequences by the spring of 2000. This accomplishment, even though not cloning, presents other new issues for individuals and society. For this reason the Ethical, Legal, and Social Implications (ELSI) was brought in to identify and address these issues. They operate to secure the individuals rights to those who contribute DNA samples for studies. The ELSI, being the biggest bioethics program, has to decide on important factors when an individual’s personal DNA is calculated. Such factors would include; who would have access to the information, who controls and protects the information and when to use it? Along with these concerns, the ESLI tries to prepare for the estimated impacts that genetic advances could be responsible for in the near future. The availability of such information is becoming to broad and one needs to be concerned where society is going with it.
By using identified gene mutations that are known to cause diseases, asymptomatic individuals are able to discover if they are at risk for specific genetic conditions; this is known as genetic testing. Unfortunately, genetic testing can vary in its predictive ability. For example, Huntington disease, Duchenne Muscular Dystrophy, Fragile X syndrome and multiple endocrine neoplasia type 2 are conditions that can be determined by genetic testing (Samen, 1996). In contrast, for multifaceted diseases like Alzheimer’s, breast and ovarian cancer and colorectal cancer, predisposition can be determined with genetic testing. However, an absolute diagnosis of those diseases cannot be made (Heshka et al., 2008).
Brooks, Jamie D., King, Meredith L., (2008). Geneticizing Disease. Implications for Racial Health Disparities. Center for American Progress. Progressive Ideas for a Strong, Just, and Free America. Retrieved from https://www.geneticsandsociety.org/downloads/2008_geneticizing_disease.pdf
A mutation in the BRCA1 or BRCA2 gene is associated with an increased risk of ovarian cancer
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About 12% of women in the United States will develop breast cancer in their lifetime, more than any other type of cancer (www.breastcancer.org, 2015). Many people lack the knowledge of how breast cancer is developed. Some people think they will not get cancer because they do not smoke cigarettes, but this is not the only cause of cancer developing in the breast. Anyone can get cancer. Everyone is potentially at risk for developing some form of Cancer (American Cancer Society, 2015).
Whereas Nationalism did emerge following the war of 1812, it was quickly squashed down and overshadowed by the growing sectionalism and tension in the United States. Tariffs, the National Bank, and slavery all played a role in further dividing the nation and securing that sectionalism would prevail. Even though the period was traditionally labeled as the “Era of Good Feelings”, it was anything but, thanks to the emergence of sectionalism and the division of the North and South.
In the article “Individual Autonomy and Social Structure”, Dorothy Lee talks about individual autonomy. She goes through the topic by examining different groups such as; the Wintu Indians of California, the Sikh family, the Navaho Indians of Arizona and New Mexico, and the Chinese culture. All of these different groups and societies give personal freedom to the individuals regardless of age groups. The example of Navaho Indians is used by Lee to demonstrate how “personal autonomy is supported by the cultural framework” (Lee, 1959, p.5). She points out the individual autonomy of non-western societies to the individuality of western society. One group gives full independence to an individual while the other does not and puts restrictions in place through some form. She states “...in a heterogeneous society such as ours, and in an era of induced change and speeded temp of living, it has been difficult to implement this tenet in the everyday details of living” (Lee, 1959, p.5). She points out the fast living pace of western society, where the personal autonomy given from the other cultures is lacking.
The Human Genome Project is the largest scientific endeavor undertaken since the Manhattan Project, and, as with the Manhattan Project, the completion of the Human Genome Project has brought to surface many moral and ethical issues concerning the use of the knowledge gained from the project. Although genetic tests for certain diseases have been available for 15 years (Ridley, 1999), the completion of the Human Genome Project will certainly lead to an exponential increase in the number of genetic tests available. Therefore, before genetic testing becomes a routine part of a visit to a doctor's office, the two main questions at the heart of the controversy surrounding genetic testing must be addressed: When should genetic testing be used? And who should have access to the results of genetic tests? As I intend to show, genetic tests should only be used for treatable diseases, and individuals should have the freedom to decide who has access to their test results.
The "Genetic Screening" Genetic Screening. NDSU,. Web. The Web. The Web.
On the other hand, Rousseau provides a more enlightened approach. He claims that in the state of nature, men are inherently innocent and are born with the potential of goodness. It is not that humans are intrinsically cruel and malicious to one another; it is that the social systems that are in place propagate animosity. With the establishment of political societies, inequalities arise, dividing extremes of poverty and wealth. The conflict between Hobbes’ and Rousseau’s perspective is that Hobbes believed that this clashing between individuals was simply a key feature of human nature, while Rousseau believed this was brought on throughout the course of social development. For that reason, each man’s belief of the natural state of men sets the
Genetic testing, also known as screening, is a rapidly advancing new scientific field that can potentially revolutionize not only the world of medicine, but many aspects of our lives. Genetic screening is the sequencing of human DNA in order to discover genetic differences, anomalies, or mutations that may prove pathological. As genetic screening becomes more advanced and easily accessible, it presents society with difficult questions that must be asked about the boundaries of science and to what degree we are allowed to tamper with the human genome. To better understand the potential impact of genetic screening on our society, we must examine the potential benefits in comparison to the possible negative impact it may cause. With this knowledge in hand, we can examine what the future holds for this field of study and the best possible direction to take.